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Fentanyl Vaccine [?] Potential ‘Game Changer’ for Opioid Epidemic
neurosciencenews.com ^ | November 14, 2022 | University of Houston

Posted on 11/14/2022 4:12:28 PM PST by BenLurkin

A research team led by the University of Houston has developed a vaccine targeting the dangerous synthetic opioid fentanyl that could block its ability to enter the brain, thus eliminating the drug’s “high.”

The breakthrough discovery could have major implications for the nation’s opioid epidemic by becoming a relapse prevention agent for people trying to quit using opioids. While research reveals Opioid Use Disorder (OUD) is treatable, an estimated 80% of those dependent on the drug suffer a relapse.

The findings, published in the journal Pharmaceutics, could not be timelier or more in demand: Over 150 people die every day from overdoses of synthetic opioids including fentanyl, which is 50 times stronger than heroin and 100 times stronger than morphine. Consumption of about 2 milligrams of fentanyl (the size of two grains of rice) is likely to be fatal depending on a person’s size.

In another positive finding, the vaccine did not cause any adverse side effects in the immunized rats involved in lab studies. The team plans to start manufacturing clinical-grade vaccine in the coming months with clinical trials in humans planned soon.

“The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,” said Haile.

(Excerpt) Read more at neurosciencenews.com ...


TOPICS: Science
KEYWORDS: fentanyl; fentanylvaccine; vaccine
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1 posted on 11/14/2022 4:12:28 PM PST by BenLurkin
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To: BenLurkin

Vaccine is a word which now means: “stuff we want you to take”.


2 posted on 11/14/2022 4:16:33 PM PST by ClearCase_guy (We are already in a revolutionary period, and the Rule of Law means nothing. )
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To: BenLurkin

Sure — an addict is going to want a vaccine so he doesn’t get high.


3 posted on 11/14/2022 4:16:46 PM PST by George from New England
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To: BenLurkin

Sure I would trust them completely to come up with a safe option . Just like they did for Covid 19.


4 posted on 11/14/2022 4:17:32 PM PST by dvan (Send Them Home!Napolatono)
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To: BenLurkin

This sounds a lot like modern pharma where they prescribe a new drug to counter the effects of the drug they have been prescribing.

A simpler solution would be to stop the flow of fentanyl.


5 posted on 11/14/2022 4:18:10 PM PST by Presbyterian Reporter
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To: BenLurkin

How about if you get a shot of narcan for an overdose, the EMT gives you the fentanyl ‘vaccine’ right afterward?


6 posted on 11/14/2022 4:20:18 PM PST by dynachrome (“We cannot save Ukraine by dooming the US economy.” Rand Paul)
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To: BenLurkin

Not going to make much difference. We have had disulfiram for alcoholics for decades now and we still have drunks killing themselves and others with abandon.


7 posted on 11/14/2022 4:20:19 PM PST by hinckley buzzard ( Resist the narrative)
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To: BenLurkin

Sounds great, until you actually need pain medication.


8 posted on 11/14/2022 4:23:58 PM PST by monkeyshine (live and let live is dead)
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To: monkeyshine

They claim you can still get relief from morphine.


9 posted on 11/14/2022 4:27:13 PM PST by BenLurkin (The above is not a statement of fact. It is either opinion, or satire, or both.)
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To: BenLurkin

Fentanyl vax? Back to licking toads.


10 posted on 11/14/2022 4:28:29 PM PST by Qiviut (I'm not out of control, I'm just not in their control. $hot $hills: Sod Off)
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To: BenLurkin
Got any sources for that? Doctors are mighty stingy.

asking for a friend

11 posted on 11/14/2022 4:32:47 PM PST by BipolarBob (I was born into this world with nothing . . and I still have most of it .)
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To: ClearCase_guy

Totally useless. People that want to take these drugs are going to.

They aren’t interested in some ridiculous vaccine.

Vaccine implies protection from an unwanted invasion to the host.

This is clearly not the case.

Utterly stupid


12 posted on 11/14/2022 4:33:37 PM PST by Hammerhead
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To: BenLurkin

Too bad it is fentanyl-specific and doesn’t block urges for other opioids.


13 posted on 11/14/2022 4:40:22 PM PST by ProtectOurFreedom (If you're not part of the solution, you're just scumming up the bottom of the beaker!)
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To: Qiviut

I’m smoking banana peels again…


14 posted on 11/14/2022 4:40:51 PM PST by EEGator
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To: monkeyshine
Last sentence of the excerpt...
“The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,”

15 posted on 11/14/2022 4:41:39 PM PST by ProtectOurFreedom (If you're not part of the solution, you're just scumming up the bottom of the beaker!)
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To: EEGator
Electrical banana gonna be a sudden craze.
Electrical banana gonna be the very next phase.
They call it Mellow Yellow (quite rightly).
16 posted on 11/14/2022 4:42:47 PM PST by Publius
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To: BipolarBob

They quoted this person in the article. I don’t know if they are right or not.

“The anti-fentanyl antibodies were specific to fentanyl and a fentanyl derivative and did not cross-react with other opioids, such as morphine. That means a vaccinated person would still be able to be treated for pain relief with other opioids,” said Haile.


17 posted on 11/14/2022 4:42:51 PM PST by BenLurkin (The above is not a statement of fact. It is either opinion, or satire, or both.)
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To: BenLurkin

No thanks. Fentanyl is the most potent pain killer we have when used properly.

The dopeheads that take stuff they don’t know.... let them off themselves. Good riddance


18 posted on 11/14/2022 4:43:22 PM PST by clee1 (We use 43 muscles to frown, 17 to smile, and 2 to pull a trigger. I'm lazy and don't wish to smile.)
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To: BenLurkin; ProtectOurFreedom

Fair enough. My brother-in-law was in the hospital a little while back... heart attack. Painful. They asked him “do you want fentanyl for the pain?” - just hearing the word nearly gave him another heart attack. Needless to say he isn’t a candidate for that vaccine.


19 posted on 11/14/2022 4:45:11 PM PST by monkeyshine (live and let live is dead)
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To: BenLurkin
They quoted this person in the article.

No,no,no. Sources for the heroin . . not the quote. Sheesh. I picked a bad day to give up sniffing glue.

20 posted on 11/14/2022 4:49:41 PM PST by BipolarBob (I was born into this world with nothing . . and I still have most of it .)
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