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A rhythmic small intestinal microbiome prevents obesity and type 2 diabetes (Intermittent fasting)
Medical Xpress / University of California - San Diego / Cell Reports ^ | July 5, 2022 | Scott LaFee / Ana Carolina Dantas Machado et al

Posted on 07/05/2022 9:36:30 PM PDT by ConservativeMind

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms. Researchers used mouse models to explore how diet and feeding patterns affect these intestinal microbes—and the health of the hosts, particularly with obesity and type 2 diabetes.

"It's important to realize that the gut microbiome is constantly changing, not only based on what we're eating, but also based on the time of day," said Amir Zarrinpar, MD, Ph.D.

"And what we've learned is that cyclical changes in the gut microbiome are quite important for health since they help with the circadian clock, and with that the regulation and control of glucose, cholesterol and fatty acids—and overall metabolic health."

In their latest work, Zarrinpar and colleagues further elucidate the impact and interplay of these factors, particularly in terms of the ileum and its unique functions related to digestion and absorption. Specifically, they looked at how diet-induced obesity (DIO) and time-restricted feeding (TRF) alter ileal microbiome composition and transcriptome (the protein-coding part of an organism's genome) in mouse models.

The researchers found that in mouse models, DIO and the absence of TRF (mice could eat as much as they wanted whenever they wanted) resulted in disruptions to gut microbiome rhythms and the signaling pathways that help modulate intestinal clocks. In other words, the mice became fat and unhealthy.

"It is interesting that restricting food access with TRF acts not only through restoration of patterns affected under the unhealthy state, but also through new pathways," said Ana Carolina Dantas Machado, Ph.D.

"These findings underscore the influence of diet and time restricted feeding patterns in maintaining a healthy gut microbiome, which in turn modulates circadian rhythms that govern metabolic health," said Zarrinpar.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: diabetes; healthcare; intestinalflora; microbiome; obesity; whatarethey; whichones
Tying eating down to around eight hours of the active part of the day undid most of the problems from the types of food eaten.

It doesn’t make bacteria change much, but it does make the existing the existing bacteria output metabolites that keep our bodies working properly, by being on a proper schedule.

1 posted on 07/05/2022 9:36:30 PM PDT by ConservativeMind
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20% fewer pings) or “Everything” list.

2 posted on 07/05/2022 9:36:51 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

bump for later


3 posted on 07/05/2022 9:39:30 PM PDT by GOPJ (MAGA POWER - - President Trump's endorsement record is 144-10)
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To: ConservativeMind

Ping


4 posted on 07/05/2022 10:08:23 PM PDT by hope_dies_last ( )
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To: ConservativeMind

This sounds weird but I once read something about Hitler’s doctor squirting poop from a Romanian peasant into capsules and feeding them to Hitler ... I understand the reasoning but am shocked that he would swallow them.....ewwww. It was a treatment for flatulence... (I’d rather just fart)

I did a search for this and yes, it did show up... along with a bunch more ewww...

It seems that all Der Fuhrer ate was cabbage and raw vegetables... no wonder the man had wind.

Here’s a tip, NEVER search using “hitler poop”

U been warned!


5 posted on 07/05/2022 10:57:10 PM PDT by Bobalu (A dem asked what side I was for in Ukraine, I said "I'm against the commies" -- He got real pissed!)
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To: ConservativeMind

If I could get a yogurt or something that had these microbes in them I’d be so happy because I have metabolic syndrome that is so bad that I am down to eating just lettuce with hardly any salad dressing on it


6 posted on 07/05/2022 11:03:47 PM PDT by dila813
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To: ConservativeMind

Intermittent fasting has helped me lose 40 pounds and brought my A1C down to 5.4 from over 9 just 2 years ago.

CC


7 posted on 07/05/2022 11:24:58 PM PDT by Celtic Conservative (My cats are more amusing than 200 channels worth of TV.)
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To: Celtic Conservative

Did you restrict to only certain times a day or did you go days without eating?


8 posted on 07/06/2022 12:08:27 AM PDT by Aria
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To: Aria

3 or 4 times a month I go more than 24 hours without eating. Fluids only. About once a week.

CC


9 posted on 07/06/2022 1:11:23 AM PDT by Celtic Conservative (My cats are more amusing than 200 channels worth of TV.)
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To: Celtic Conservative

A1C at 5.4? That’s now at an excellent reading.

I would bet your insulin (and obviously glucose) are also really good.


10 posted on 07/06/2022 7:13:03 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: dila813
Your body has had too much blood sugar for too long, to get you there.

A lot more physical activity through the day would help blunt this, even if you kept a similar diet.

You could stop all simple sugars, high sugar fruits, breads, etc. and favor just the most complex of carbohydrates (low Glycemic Index or Glycemic Load). You could also go low carb, for even fewer opportunities for excess blood sugar.

Intermittent fasting helps your body reset itself, regardless of diet and activity, but it will take time, if not making other changes mentioned above.

Our bodies were not meant to eat at potentially any waking hour, eat excess calories or calories we don't burn off, or eat simple sugars (breads are effectively a simple sugar, due to their five minute conversion to sugar). Even Jesus said man cannot live on bread, alone.

There are supplements that definitely help in getting rid of metabolic syndrome, but nothing is as powerful as diet and exercise. Even stomach stapling is affecting diet, but works pretty well (however, it is extreme).

11 posted on 07/06/2022 7:28:24 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Intermittent fasting can mess up your gall bladder. Better to intermittently skip the carbs only, and generally reduce calories. It’s the constant carb snacking that gives you hyperinsulinemia, which makes you fat and sick.


12 posted on 07/06/2022 7:37:14 AM PDT by Born to Conserve
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To: Celtic Conservative
Did you allow yourself alcoholic drinks while fasting?

Or is this a no no?

13 posted on 07/06/2022 7:39:14 AM PDT by A Cyrenian (MO's state motto: Let the welfare of the people be the supreme law.)
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To: ConservativeMind

Ping

Peach


14 posted on 07/06/2022 7:59:30 AM PDT by CarolinaPeach
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To: ConservativeMind

No prob. I’m on the War Room email list so have saved all the links. I’ll find it!!! Thank you.


15 posted on 07/06/2022 8:20:41 AM PDT by MayflowerMadam (Joe Biden has been protected by assault weapons his entire adult life. )
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To: Bobalu

I’ve read/heard about poop from one person with healthy a gut being transferred to someone else to treat GERD. IIRC the method was NOT via mouth — either suppository or simple surgery. Seems it worked. IDK for sure.


16 posted on 07/06/2022 8:24:36 AM PDT by MayflowerMadam (Joe Biden has been protected by assault weapons his entire adult life. )
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To: Celtic Conservative

... well done, can you share your fasting schedule, for those of us that still need to drop 40 lbs?? ....thanks in advance


17 posted on 07/06/2022 10:46:51 AM PDT by PalominoGuy
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To: dila813

go to a wellness program that works with weight

they can put you on a program to break that cycle


18 posted on 07/06/2022 11:33:44 AM PDT by Chickensoup ( Leftists totalitarian fascists are eradicating conservatives. Leftists are genocidal. )
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To: Chickensoup

Down that, going on last 6 years


19 posted on 07/06/2022 7:32:56 PM PDT by dila813
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To: ConservativeMind

6 years, done that


20 posted on 07/06/2022 7:33:33 PM PDT by dila813
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