Inhaled nitric oxide tied to improved P/F ratio in COVID-19 with ARDS (Nitric oxide helps severely ill lungs breathe better)

Medical Xpress / HealthDay / Drugs in Context ^ | Apr. 22, 2022 | Steven H Abman et al

[ConservativeMind]

Inhaled nitric oxide (iNO) is associated with improvement in the mean partial pressure of oxygen (PaO2)/fraction of inspired oxygen (FiO2) ratio (P/F ratio) among patients hospitalized with COVID-19 and mild-to-moderate acute respiratory distress syndrome (ARDS), according to a study published online April 11 in Drugs in Context.

Steven H. Abman, M.D. and colleagues conducted a retrospective medical chart review study that included patients who were aged 18 years or older with mild-to-moderate ARDS who received iNO for ≥24 hours continuously during hospitalization for COVID-19. The analysis included 37 patients at six sites.

The researchers observed an increase in P/F ratio from 136.7 at baseline to 140.3 and 151.8, respectively, at 48 and 72 hours after iNO initiation. There was a 62 percent response rate (23 patients). No patient experienced adverse events during hospitalization, including methemoglobinemia, airway injury, or worsening pulmonary edema associated with iNO. Twenty of the patients (54.0 percent) improved or remained stable according to the physician-rated Clinical Global Impression-Improvement scale score at discharge.

"This study provides additional evidence supporting a favorable benefit-risk profile for iNO in the treatment of COVID-19," the authors write. "Future randomized, placebo-controlled studies are needed to determine its potential efficacy and place in therapy."

[ConservativeMind]

This is a treatment already available for reuse in this condition.

[ConservativeMind]

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[stars & stripes forever]

Would this help people with COPD

[ClearCase_guy]

Would Nitrous Oxide work? COVID is no laughing matter.

[mdmathis6]

Not a new thing....we use it a lot in our hospital icu’s!

[Dr. Franklin]

AND it improves your speed in the 1/4 mile!

[Bonemaker]

“...Nitric oxide helps severely ill lungs breathe better...”

It will also give you an olympic class rager while you are fighting for your life!😎

[ConservativeMind]

I do wonder about that, Bonemaker.

[Bonemaker]

😎

[TexasGator]

“AND it improves your speed in the 1/4 mile!”

Nitrous oxide.

[Faith65]

Thanks.
BKMK

[thinden]

thanx for posting

[jimwatx]

Eat your beets.

https://pubmed.ncbi.nlm.nih.gov/26653541/

[RummyChick]

i have the neo 40. there is a saliva test

https://www.amazon.com/stores/page/5DFAA627-F141-412B-B4F5-5209C2F3675E

Not sure how the gene mutations in the MTHFR genes affect this. many people have at least the two.

[SgtHooper]

How about helium?

[Bob434]

was wondering that myself- or emphysema too?

[ClearCase_guy]

Off topic, but I’ve heard that the chemical symbol for Helium is now “They/Theirs”.

[jimwatx]

“Not sure how the gene mutations in the MTHFR genes affect this. many people have at least the two.”

Yeah I’m surprised that product doesn’t contain L-methylfolate instead of just methylcobalamin to account for the possible gene mutation. I assumed I was getting enough from my diet, but then bacon prices doubled so I may consider taking beetroot powder. The product you’ve listed seems quite popular but rather pricey.

[SubMareener]

You make Nitric Oxide (NO) when you HUM. This is why the Yoga OMMMM mantras work. There is also a series of exercises you can do to get an NO dump in you veins and arteries.

[BiteYourSelf]

I want to be a dentist, and be a success.😏