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New research identifies link between gut microbes and stroke
MedicalXPress / Cleveland Clinic / Cell Host & Microbe ^ | June 16, 2021 | Weifei Zhu, Ph.D., and Stanley Hazen, M.D., Ph.D., et al

Posted on 06/16/2021 8:11:10 PM PDT by ConservativeMind

New findings from Cleveland Clinic researchers show for the first time that the gut microbiome impacts stroke severity and functional impairment following stroke. The results, published in Cell Host & Microbe, lay the groundwork for potential new interventions to help treat or prevent stroke.

The research was led by Weifei Zhu, Ph.D., and Stanley Hazen, M.D., Ph.D., of Cleveland Clinic's Lerner Research Institute. The study builds on more than a decade of research spearheaded by Dr. Hazen and his team related to the gut microbiome's role in cardiovascular health and disease, including the adverse effects of TMAO (trimethylamine N-oxide)—a byproduct produced when gut bacteria digest certain nutrients abundant in red meat and other animal products.

"In this study we found that dietary choline and TMAO produced greater stroke size and severity, and poorer outcomes in animal models," said Dr. Hazen, chair of the Department of Cardiovascular & Metabolic Sciences and director of Cleveland Clinic's Center for Microbiome & Human Health. "Remarkably, simply transplanting gut microbes capable of making TMAO was enough to cause a profound change in stroke severity."

Previously, Dr. Hazen and his team discovered that elevated TMAO levels can lead to the development of cardiovascular disease. In clinical studies involving thousands of patients, they have shown that blood levels of TMAO predict future risk of heart attack, stroke and death -findings that have been replicated around the world. Earlier studies, also led by Drs. Zhu and Hazen, were the first to show a link between TMAO and enhanced risk for blood clotting.

The team found that a gut microbe enzyme critical to TMAO production called CutC drove heightened stroke severity and worsened outcomes.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: gutmicrobes; stroke
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The Cleveland Clinic found a way to block the TMAO effect: Have olive oil and/or balsamic vinegar with the choline or red meat, and it temporarily deactivates the bacteria.
1 posted on 06/16/2021 8:11:10 PM PDT by ConservativeMind
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To: ConservativeMind

Two words:

Fecal.

Transplant.


2 posted on 06/16/2021 8:12:01 PM PDT by E. Pluribus Unum ("Communism is not love. Communism is a hammer which we use to crush the enemy." ― Mao Tse-tung)
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To: ConservativeMind

Gut microbes have also been linked to Parkinson’s and Alzheimer’s.


3 posted on 06/16/2021 8:15:11 PM PDT by libh8er
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To: ConservativeMind

Have olive oil and/or balsamic vinegar with the choline or red meat, and it temporarily deactivates the bacteria.


Do you suppose our tomato caprese (served with olive oil and balsamic vinegar), that we typically have with our steaks, would count?


4 posted on 06/16/2021 8:17:36 PM PDT by Jane Long (America, Bless God....blessed be the Nation 🙏🏻🇺🇸)
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To: libh8er

Would taking a probiotic help develop the right gut microbes?


5 posted on 06/16/2021 8:18:15 PM PDT by EinNYC
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To: EinNYC; Jane Long

Great questions both of you.


6 posted on 06/16/2021 8:22:20 PM PDT by FreedomPoster (Islam delenda est)
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To: ConservativeMind

There is no money in gut bacteria, which can’t be patented. Good research, but it won’t go anywhere.


7 posted on 06/16/2021 8:24:03 PM PDT by aimhigh (THIS is His commandment . . . . 1 John 3:23)
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To: FreedomPoster

I haven’t eaten any sort of red meat for years and years. And I take “Phillips Colon Health” probiotic, as suggested by my gastroenterologist. So I wonder if these two practices cut down on the “bad” microbes.


8 posted on 06/16/2021 8:24:07 PM PDT by EinNYC
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To: ConservativeMind

Paving the way for Bill Gate’s FAKE MEAT.


9 posted on 06/16/2021 8:26:50 PM PDT by stars & stripes forever (Blessed is the nation whose God is the Lord. (Psalm 33:12))
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To: EinNYC

It should but it’s important to create a gut environment that’s favorable to the good bacteria (more fiber, vegetables, less sugar etc)


10 posted on 06/16/2021 8:27:01 PM PDT by libh8er
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To: libh8er
It should but it’s important to create a gut environment that’s favorable to the good bacteria (more fiber, vegetables, less sugar etc)

I eat very little sugar and always try to have veggies and fruits every day. I only use whole grain bread and brown rice. And I take a good multivitamin which is food-based, not chemical-based, plus extra vitamin D3 and fish oil. I hope I'm covering all my bases.

11 posted on 06/16/2021 8:30:02 PM PDT by EinNYC
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To: EinNYC
Sauerkraut
12 posted on 06/16/2021 8:31:48 PM PDT by Karl Spooner
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To: EinNYC

“I hope I’m covering all my bases. “

Add exercise to forestall chronic cardio vascular disease.


13 posted on 06/16/2021 8:36:51 PM PDT by Mariner (War Criminal #18)
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To: ConservativeMind

A very fit friend (vigorous bike riding, ice hockey, hiking) suddenly hit a wall recently and had chest pain. He wound up with a stent for a blocked coronary artery. His doctor told him “no more animal foods” and he has gone whole hog (so to speak) on a plant-based diet. No milk, no dairy at all, no meat (not even fish or poultry). It’s got to be rough because he loves going crabbing and salmon fishing.


14 posted on 06/16/2021 8:37:41 PM PDT by ProtectOurFreedom ("Pour les vaincre il faut de l'audace, encore de l'audace, toujours de l'audace")
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To: EinNYC

That sounds good. In addition regular exercise, quality sleep, low stress and a moderate amount of sunshine will keep your immune system in good shape (immune health is affected by gut biome).


15 posted on 06/16/2021 8:40:03 PM PDT by libh8er
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To: Jane Long

Of course, if enough.


16 posted on 06/16/2021 8:41:40 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Karl Spooner

I have a sauerkraut crock that I’ve never used. Probably should give it a try.


17 posted on 06/16/2021 8:43:52 PM PDT by Jane Long (America, Bless God....blessed be the Nation 🙏🏻🇺🇸)
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Mark for video


18 posted on 06/16/2021 9:03:05 PM PDT by Bigg Red (Trump will be sworn in under a shower of confetti made from the tattered remains of the Rat Party.)
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To: EinNYC

Yogurt contains probiotics. I have it every night for dessert. Lemon yogurt with organic blueberries. Yum. Better than ice cream.

https://www.yogurtinnutrition.com/yogurt-affects-gut-microbiota/


19 posted on 06/16/2021 9:03:39 PM PDT by Veto! (Political Correctness Offends Me)
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To: Jane Long

Cabbage, salt, water are all you need.


20 posted on 06/16/2021 9:06:07 PM PDT by tinamina
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