Posted on 05/21/2021 3:01:08 PM PDT by FreedomForce
Abstract
COVID 19 is known to cause immune dysregulation and vitamin D is a known immunomodulator. This study aims to objectively investigate the impact of Pulse D therapy in reducing the inflammatory markers of COVID-19. Consented COVID-19 patients with hypovitaminosis D were evaluated for inflammatory markers (N/L ratio, CRP, LDH, IL6, Ferritin) along with vitamin D on 0th day and 9th/11th day as per their respective BMI category. Subjects were randomised into VD and NVD groups. VD group received Pulse D therapy (targeted daily supplementation of 60,000 IUs of vitamin D for 8 or 10 days depending upon their BMI) in addition to the standard treatment. NVD group received standard treatment alone. Differences in the variables between the two groups were analysed for statistical significance. Eighty seven out of one hundred and thirty subjects have completed the study (VD:44, NVD:43). Vitamin D level has increased from 16 ± 6 ng/ml to 89 ± 32 ng/ml after Pulse D therapy in VD group and highly significant (p < 0.01) reduction of all the measured inflammatory markers was noted. Reduction of markers in NVD group was insignificant (p > 0.05). The difference in the reduction of markers between the groups (NVD vs VD) was highly significant (p < 0.01). Therapeutic improvement in vitamin D to 80–100 ng/ml has significantly reduced the inflammatory markers associated with COVID-19 without any side effects. Hence, adjunctive Pulse D therapy can be added safely to the existing treatment protocols of COVID-19 for improved outcomes.
(Excerpt) Read more at nature.com ...
Yeah, I take some K2, too.
I think the RDA was set just based on what’s needed for bone health.
Ah - I take the K2+D3 combo plus zinc.
mmm. I think 0.05 is the threshold the FDA uses for clinical trial studies. Not 0.5. 0.01 works.
But 60,000 iu is not a normal dose. I take 5,000 iu daily. I’m not gonna swallow a dozen of them a daily but I don’t know what “pulse D” is.
My brother in law has a severe problem absorbing vitamin D, which caused bone and teeth issues.
The Dr gave him a script for a weekly vitamin D “bomb” 50,000 units. He has been on it for years.
FYI, he is over 60, got covid and his only symptoms were headache and the taste thing.
Ping!
You mean “bone health” as in “Look, Mom! No rickets!” ? :-D
“Pulse D therapy is a targeted approach to increase the serum vit.D level by using high dose (60,000 IUs) oral supplementation of vit.D daily for a specific period of time determined by the individual’s BMI, initial level of vit.D and the formulation19.”
They gave the patients something called Deksel Nano Syrup which is D3 liquid.
yikes.....
I did not read the article, but I’m recently out of the hospital from a bout with the unknown. The unknown set me off into some crazy World I can’t remember being. I only know what happened by those that were with me in the hospital, and my wife who spent every hour of every day for two weeks to get me out of there.
The experience cost me two months of my life with no memory of what happened, and wreaked havoc with my entire system.
The VA doctor assigned figured out what happened finally, and only recently. I had been ingesting too much vitamin D in fear of catching the CCP virus, which in turn caused my calcium count to spike, and consequently some sort of chain reaction occurred.
We are still trying to find out more about what happened, but please anybody inclined to take vitamin D do so with caution, and refrain from the old “well, if one is good for me, then a second will be even better” we all tell ourselves occasionally.
The VA assigned hospice personnel were asking me, and my wife to provide them with the name of our preferred mortuary. So far we haven’t done so as it appears we are beating this thing.
Not yikes but 6000 IU is plenty, in my opinion.
How much were you taking a day?
That’s strange one. I’ve never heard of that before. How much D were you taking?
Thanks. Liquid makes more sense.
Another way of thinking about the p value, 0.05 means it is a 95% chance the results are not the result of a fluke or random chance (one in 20). 0.01 means it is 99% chance it’s not a fluke (one in 100). 0.5 is, thus, a coin toss (50:50).
But this alone is not enough to tell you much. A lot of other variables to consider. You really need a large sample size, and good controls on the test subjects to rule out outside factors, and clear objectives pre-defined. I’m not poopooing the study, I am personally convinced Vitamin D plays a role in overall health (I don’t think anyone disputes that) and as anti-covid therapy as well (some debate that, though I don’t know why I think those people are weirdos).
I take enough D3 to be worried about it. one small pill of 50,000IU 2x/wk. also NAC, K2, Quercitin, zinc, C daily.
Have you had your D3 levels been tested? That’s best way to know how much to take...I require about 10,000iu a day to maintain level between 60-80 ... people are different
fwiw
I went to the Costco pharmacy and asked the pharmacist what was the difference between D and D3.
He leaned forward and told me ‘there is no difference at all’.
I bought a 2 pack of D3, 360 tabs each and take one every day, or two or three as I think of it.
RDA’s are a national joke.
1000 IU per tab
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