Posted on 02/13/2021 6:39:39 PM PST by SeekAndFind
Early treatment with a medication commonly used to treat asthma appears to significantly reduce the need for urgent care and hospitalization in people with COVID-19, researchers at the University of Oxford have found.
The STOIC study found that inhaled budesonide given to patients with COVID-19 within seven days of the onset of symptoms also reduced recovery time. Budesonide is a corticosteroid used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD).
Findings from the phase 2 randomized study, which was supported by the NIHR Oxford Biomedical Research Centre (BRC), were published on the medRxiv pre-print server.
The findings from 146 people—of whom half took 800 micrograms of the medication twice a day and half were on usual care—suggests that inhaled budesonide reduced the relative risk of requiring urgent care or hospitalization by 90% in the 28-day study period. Participants allocated the budesonide inhaler also had a quicker resolution of fever, symptoms and fewer persistent symptoms after 28 days.
Professor Mona Bafadhel of the University's Nuffield Department of Medicine, who led the trial, said: 'There have been important breakthroughs in hospitalized COVID-19 patients, but equally important is treating early disease to prevent clinical deterioration and the need for urgent care and hospitalization, especially to the billions of people worldwide who have limited access to hospital care.
'The vaccine programs are really exciting, but we know that these will take some time to reach everyone across the world. I am heartened that a relatively safe, widely available and well studied medicine such as an inhaled steroid could have an impact on the pressures we are experiencing during the pandemic.'
The study also demonstrated that there was a reduction in persistent symptoms in those who received budesonide. Prof Bafadhel, a Respiratory Consultant also working at the Oxford University Hospitals NHS Foundation Trust, said: 'Although not the primary outcome of study, this is an important finding. I am encouraged to see the reduction in persistent symptoms at 14 and 28 days after treatment with budesonide. Persistent symptoms after the initial COVID-19 illness have emerged as a long-term problem. Any intervention which could address this would be a major step forward.'
The trial was inspired by the fact that, in the early days of the pandemic, patients with chronic respiratory disease, who are often prescribed inhaled steroids, were significantly under-represented among those admitted to hospital with COVID-19.
bttt
It this were during POTUS Trump’s term, would be declared Off Label and not legal.
So easily that we did not even know I had had it until they found I was chock full of antibodies.
Budesonide via nebuliser is what I normally use when I have a bad time with my asthma.
Sorry. Only a risky experimental vaccine that puts billions of dollars into the pockets of the oligarchs will do. Too bad. So sad.
It's not prescription. You can get it off the shelf at any drug store, even Walmart.
What you get off the shelf is not the same. I have both.
Of course, off the shelf is better than nothing but you would be better off getting the script version if you get COVID
Was going to say the same thing. Had COVID-like symptoms in late February to the point where I ended up in the ER. They gleefully told me it was not the flu - the “fun” started a couple weeks later - and I’m anecdotally sure my multiple asthma Rx’s were the reason I didn’t die.
Thanks.
There is an OTC version. For example, at Walmart
Equate Non-Drowsy Budesonide Nasal Spray 32mcg, 120 sprays
I would definitely use it while trying to get the script.
It is not the cheapest drug but very effective. A doctor told the world he had a 100% effective treatment with all his COVID patients in July or August. I have been using it for the past 5 years.
Good God...it sounds like that Budesonide with HCQ or Ivermectin would have probably cut deaths by 75% to 90%. But "get Trump" prevented all of that.
Is Budesonide a Coronavirus Treatment? Experts Weigh in About COVID-19, by Stephanie Dube Dwilson, July 10, 2020, Heavy.com.
But does the bad orangeman who is bad know about it?
Thanx for sharing your personal experience.
Buddescide,,,
The Surfers’ Cure!
.
Thanks
Wife had COVID pneumonia way back in early March before the advent of strict rules on what may or may not be prescribed. He gave her albuterol, that’s a standard asthma nebulizer, and an antibiotic injection. She was totally recovered in three days.
And yet again: Duh. It has a bactericidal effect. There are papers discussing this almost a decade ago.
PG is safer.
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