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See the face of your 100,000-year-old ancestor
The Jerusalem Post ^ | By Maayan Jaffe-Hoffman September 19, 2019 20:32

Posted on 09/19/2019 10:42:50 AM PDT by Red Badger

Israeli team used DNA to design first Denosivan replica

Portrait of a female Denisovan teen. (photo credit: MAAYAN HAREL)

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Meet “Denise,” the first reconstructed anatomical profile of what, until now, were considered the mysterious Denisovans, a group of archaic humans.

She was revealed on Thursday by researchers at the Hebrew University of Jerusalem. The team who managed to recreate her profile say that long-term, their research shows possible strategies that could be taken for forensic applications.

Denisovans lived in Siberia and Eastern Asia before going extinct approximately 50,000 years ago, said Hebrew University researcher Prof. Liran Carmel, who led the study. But exactly what Denisovans might have looked like had previously been anyone’s guess. Since their original discovery in 2008, researchers had only three fossils to work with: a bone from the tip of “Denise’s” pinkie finger, a few teeth and a recently found lower jaw bone. The researchers were able to reconstruct the Denisovan profile over a three-year period by examining patterns of methylation in their ancient DNA.

3-D printed reconstruction of a female Denisovan (Credit: Maayan Harel)3-D printed reconstruction of a female Denisovan (Credit: Maayan Harel)

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DNA methylation is a process by which methyl groups are added to the DNA molecule, thereby changing the activity of a segment of DNA. “Methylation provides ample information on gene transcription,” Carmel explained.

By studying Denisovan DNA methylation maps and comparing them to those of Neanderthals – another group of archaic humans who went extinct in Europe about 40,000 years ago – as well as ancient Homo sapiens, the team was able to understand what the differences might mean to Denisovan anatomical features, based on what is known about human disorders in which those genes lose their function.

“We got a prediction as to what skeletal parts are affected by differential regulation of each gene and in what direction that skeletal part would change – for example, a longer or shorter femur bone,” said Dr. David Gokhman, now a postdoc at Stanford, who also worked on the project.

Carmel said it is very difficult to get an anatomical profile from a DNA sequence: at most, scientists and forensics teams can tell basic details, such as whether the person has dark hair or skin. DNA methylation, however, allows researchers to make much more detailed anatomical predictions.

The team was able to prove about 85% accuracy of their model by using the same methodology to create anatomical models of Neanderthals and chimpanzees, which have known anatomical profiles.

“One of the most exciting moments happened a few weeks after we sent our paper to peer-review,” Carmel said. “Scientists had discovered a Denisovan jawbone. We quickly compared this bone to our predictions and found that it matched perfectly. Without even planning it, we received independent confirmation of our ability to reconstruct whole anatomical profiles using DNA that we extracted from a single fingertip.”

The researchers found that Denisovans have striking similar methylation patterns to humans. They also found that there are 56 anatomical features in which Denisovans differ from modern humans and/or Neanderthals, 34 of them in the skull.

Past research done outside of Hebrew University showed that up to 6% of present-day Melanesians and Aboriginal Australians contain Denisovan DNA. Further, Denisovan DNA likely contributed to modern Tibetans’ ability to live in high altitudes and to Inuits’ ability to withstand freezing temperatures.

Although Carmel said that “using our method directly for forensic application is currently not possible,” because it is designed to study differences outside the variability of modern humans and police would need to find features within that variability, “DNA methylation may provide much information that could help the police,” with forensic data, according to Carmel.


TOPICS: Arts/Photography; History; Religion; Society
KEYWORDS: archaeology; denosivan; denosivans; genetics; ggg; godsgravesglyphs; helixmakemineadouble; history; paleontology
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To: Red Badger

61 posted on 09/19/2019 12:48:30 PM PDT by Long Jon No Silver
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To: jonascord

I think they proved the reactors work when they killed a lot of stuff.

But Carbon 14 dating might not be all it’s cracked up to be.
Some Creation Scientists took fossils that were supposed to be millions of years old and carbon dated them. They should have shown almost no Carbon 14. Instead they showed lots of Carbon 14.

I don’t know, but evolutionists claim that the Oldawan people had tools 2.3 million years ago. If you think I scoff at 100,000 years, you can imagine how bowled over with laughter I am at tool bearing man 2.3 million years ago.

Evolutionist’s response to that is to say, the Carbon 14 they detected was background level and was leached into the ancient fossils by ground water.

Which causes me to ask, if it can leach in, can it not leach out? And if there was a flood, or ground water over a couple of hundred to thousands of years and Carbon 14 is leachable, is it reliable at all?


62 posted on 09/19/2019 12:50:16 PM PDT by DannyTN
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To: jonascord

Dang, got the response out of order. Should read like this.

I think they proved the reactors work when they killed a lot of stuff.

But Carbon 14 dating might not be all it’s cracked up to be.
Some Creation Scientists took fossils that were supposed to be millions of years old and carbon dated them. They should have shown almost no Carbon 14. Instead they showed lots of Carbon 14.

Evolutionist’s response to that is to say, the Carbon 14 they detected was background level and was leached into the ancient fossils by ground water.

Which causes me to ask, if it can leach in, can it not leach out? And if there was a flood, or ground water over a couple of hundred to thousands of years and Carbon 14 is leachable, is it reliable at all?

I don’t know, but evolutionists claim that the Oldawan people had tools 2.3 million years ago. If you think I scoff at 100,000 years, you can imagine how bowled over with laughter I am at tool bearing man 2.3 million years ago.


63 posted on 09/19/2019 12:51:47 PM PDT by DannyTN
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To: txnativegop

Yeah, but according to evolutionists, we had tools 2.3 million years ago.

So we not only were making tools, but we were smart enough to make tools. And we couldn’t figure out now to protect ourselves from wolves and bears?


64 posted on 09/19/2019 12:53:56 PM PDT by DannyTN
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To: Long Jon No Silver

I was wondering when that pic would make an appearance...


65 posted on 09/19/2019 12:56:26 PM PDT by Carpe Cerevisi
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To: DannyTN
The Moon landing was filmed on a sound stage in Burbank.
There was an alien landing at Roswell.
The WTC was blown up by the CIA/Illuminati/Free Masons/Boy Scouts, and the planes were actually flown into the South Atlantic.
Antarctica is actually a huge ice wall that stops the oceans from draining off the Edge.

Nope, ain't going there.

66 posted on 09/19/2019 1:00:05 PM PDT by jonascord (First rule of the Dunning-Kruger Club is that you do not know you are in the Dunning-Kruger club.)
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To: Ancesthntr; Red Badger

Old news. I hit that 100,000 years ago.


67 posted on 09/19/2019 1:13:56 PM PDT by Lazamataz (We can be called a racist and we'll just smile. Because we don't care.)
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To: CTrent1564

Beer eyes. All that remains is determining the date of the inception of brewing.


68 posted on 09/19/2019 1:19:58 PM PDT by chulaivn66 ("...government will follow its natural tendency to despotism.")
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To: DannyTN

excellent chart, tks for posting.


69 posted on 09/19/2019 1:21:23 PM PDT by nicollo (I said no!)
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To: brianr10

Exactly.


70 posted on 09/19/2019 1:22:39 PM PDT by miliantnutcase
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To: Red Badger

71 posted on 09/19/2019 1:24:55 PM PDT by mbarker12474
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To: Mariner

That encoding persists today as exemplified by Je$$e Jaxson and Al $harkton ?


72 posted on 09/19/2019 1:47:23 PM PDT by litehaus (A memory toooo long.............)
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To: chulaivn66

Does have nice eyes.


73 posted on 09/19/2019 1:52:01 PM PDT by CTrent1564
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To: Red Badger

What I don’t get is, if humans suddenly evolved into modern homosapiens 100,000 years ago or so, shouldn’t we have evolved beyond that now? Shouldn’t we all be X-men by now? Evolutionists never seem to address this problem, the idea that we have stopped evolving.


74 posted on 09/19/2019 1:52:32 PM PDT by gop4lyf (Gay marriage is neither. Democrats are the party of sore losers and pedophiles.)
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To: gop4lyf

We are still ‘evolving’.....................


75 posted on 09/19/2019 2:08:16 PM PDT by Red Badger (Against stupidity the gods themselves contend in vain......................)
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To: central_va

She doesn’t look a day over 86,000


76 posted on 09/19/2019 2:13:26 PM PDT by Buckeye McFrog (Patrick Henry would have been an anti-vaxxer.)
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To: z3n

with make up and without

(Or as my Mom or my Aunt used to say before going anywhere... wait and let me put my face on)


77 posted on 09/19/2019 2:28:29 PM PDT by TexasTransplant (Damn the Torpedoes! Full Speed Ahead!)
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To: DannyTN
There was a mass extinction 12,000 years ago and a repeated bottleneck on that same 12,000 year cycle. Some think it is because of our Sun, the cycle of micro novas and cosmic rays. We are due again.

Carrying capacity has increased with technology. Mass extinctions wipe out more than life. Do you ever wonder how ancient megaliths were built ubiquitously around the globe? It would have taken highly evolved cultures, organization and technology. POOF! Gone. Everything, but the stone structures.

Just something to consider.

Do you know mitochondria is only about 100,000 years old?
78 posted on 09/19/2019 2:38:51 PM PDT by PA Engineer (Liberate America from the Occupation Media.)
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To: PA Engineer

I guess the humans 2.3 million years ago didn’t have mitochondria. Maybe they had pre-mitochondria.


79 posted on 09/19/2019 2:43:31 PM PDT by DannyTN
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To: Lazamataz

*** “Old news. I hit that 100,000 years ago” ***

We know (because we noticed the resemblance to Raquel Welch) who would doubt that you definitely hit that?

I do have a question ... that fur bra ... Was it Snap, Hook or a slipover?


80 posted on 09/19/2019 2:56:43 PM PDT by TexasTransplant (Damn the Torpedoes! Full Speed Ahead!)
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