Posted on 05/17/2019 11:23:17 AM PDT by ConservativeMind
Researchers led by a team from The University of Texas Medical Branch at Galveston were able to dramatically reduce the pain of fibromyalgia patients with medication that targeted insulin resistance.
This discovery could dramatically alter the way that chronic pain can be identified and managed.
The UTMB team of researchers, along with collaborators from across the U.S., including the National Institutes of Health, were able for the first time, to separate patients with fibromyalgia from normal individuals using a common blood test for insulin resistance, or pre-diabetes. They then treated the fibromyalgia patients with a medication targeting insulin resistance, which dramatically reduced their pain levels.
"Earlier studies discovered that insulin resistance causes dysfunction within the brain's small blood vessels. Since this issue is also present in fibromyalgia, we investigated whether insulin resistance is the missing link in this disorder," Pappolla said. "We showed that most—if not all—patients with fibromyalgia can be identified by their A1c levels..."
Pre-diabetics with slightly elevated A1c values carry a higher risk of developing central (brain) pain, a hallmark of fibromyalgia and other chronic pain disorders."
When compared with age-matched controls, the A1c levels of the fibromyalgia patients were significantly higher.
"Considering the extensive research on fibromyalgia, we were puzzled that prior studies had overlooked this simple connection," said Pappolla. "The main reason for this oversight is that about half of fibromyalgia patients have A1c values currently considered within the normal range. However, this is the first study to analyze these levels normalized for the person's age, as optimal A1c levels do vary throughout life. Adjustment for the patients' age was critical in highlighting the differences between patients and control subjects."
For the fibromyalgia patients, metformin, a drug developed to combat insulin resistance was added to their medications. They showed dramatic reductions in their pain levels.
(Excerpt) Read more at medicalxpress.com ...
Metformin is the one diabetes-related drug I would gladly take. It functions a lot like an antioxidant. People have longer lifespans if they take it—as if it were a vitamin.
If only they would combine it with opium for its constipation effect.
How about Metform-Imodium?
Intermittent fasting lowers the body’s insulin level. People are reporting coming off of diabetic drugs due to fasting.
One reason that Metformin users have a longer life span, may be that Metformin is an AMPK activator.
Take Alpha Lipoid Acid and your A 1 C will level off. Buy it at Walmart
Watch it Danny. Big Pharma doesn't like natural free cures to mess with their profits.
Look into “Alpha Lipoic Acid” on YouTube and Amazon.
magnesium helps to balance sugar (and reduce the calcium coating around cells that makes them insulin resistant) and hugely reduces body pain
Well the main drug used to treat Fibromyalgia is Lyrica. A drug given to depression and bipolar chicks. So I think that tells us a lot about Fibromyalgia.
By the way, there are no diagnostic tests for fibromyalgia.
The “disease” and the treatment exist between the ears.
Fibromyalgia may be Centrally Mediated pain hypersensitivity
https://www.medscape.com/viewarticle/839524
https://medicalxpress.com/news/2018-09-people-fibromyalgia-inflammation-brain.html
https://www.the-rheumatologist.org/article/hypersensitivity-to-non-painful-events-may-be-part-of-pathology-in-fibromyalgia/
https://www.fibromyalgia-authority.com/2018/06/17/neuroimaging-in-fibromyalgia/
Metformin destroys the kidneys. I took this med for almost two decades. Now on insulin because Metformin destroyed my kidneys.
https://www.webmd.com/diet/qa/can-you-get-alphalipoic-acid-naturally-from-foods “Many foods contain alpha-lipoic acid in very low amounts. They include spinach, broccoli, yams, potatoes, yeast, tomatoes, Brussels sprouts, carrots, beets, and rice bran. Red meat — particularly organ meat — is also a source of alpha-lipoic acid.”
Toss the high carbed potatoes, yams and rice bran. “Low amounts” is better than nothing.
People who are up to speed with the latest on diabetes treatment [i.e., eliminating carbs, of all types] are not surprised by this.
Others, who continue to believe their doctors [who are more often than not controlled by Big Carb], will not believe any of this.
‘Watch it Danny. Big Pharma doesn’t like natural free cures to mess with their profits.’
I second that. The LAST THING that Big Pharma wants to see is people realizing that fasting for several days [on a regular basis], and thereby resetting their bodies, ends both the need for diabetic drugs, and diabetes itself.
Thankfully they’ve bought off the entire federal government and the ADA, so most diabetics are still believing that they must still eat ‘healthy’ carbs [LOL] and NEVER skip a meal, much less a day or more of eating...even if it is EXACTLY what is usually needed. So Big Pharma is safe, for now at least.
Actually it's not. Lyrica is pregabalin (an antiepileptic drug approved by the FDA in 2004). It is a piss poor pain reliever. Take too many (slang: "budweiser" in the UK) and it will GIVE you seizures.
Thanks for the links. Very interesting
“Big Pharma doesn’t like natural free cures to mess with their profits”
Nor does Big Food and Big Health.
The major health associations like the Diabetes, Heart, Cancer accept large donations from Big Food outfits like Burger King, Taco Bell, etc.
Check out this video. Kinda long. But just watch the first ten and the last ten minutes to get the gist of it.
https://www.youtube.com/watch?v=Og62hbNl794
The psych patients are the only ones who ever mention Fibromyalgia when asked about their medical histories. In my ambulance, anyway.
What a ridiculously uninformed remark.
I battled fibro symptoms for 9 years. Constant pain, migraines that lasted for months without relief, my joints swelled so badly it would make holding a pen painful, chronic fatigue due to insomnia. I wouldn’t wish it on my worst enemy.
Lyrica caused the right side of my face to collapse like a Bells Palsy seizure. I told my husband to divorce me because I didnt want him shackled to a lifetime as caregiver.
I was not out of shape. 5’8” and 140 lbs after 3 kids, I could still rock a dress and heels. It took years, and thousands in doctors Bill’s, to finally find a cure - food allergies. Changed my diet, used a system cleanse, and 9 years of agony disappeared in 3 days.
In my head? If you said that to my husband, he would pummel you into the dirt for such an insult.
Who imparted that piece of TRASH info to you? I’ve dealt with FMS for 35 yrs+, crap was a Syndrome when the Rheumatologist first diagnosed it. They are close to a blood test for it now.
Lyrica is a CRAP ADDICTIVE DRUG as is Neurotin. Worse than Heroin. Is Lyme’s, Lupus, a Imagined Disease? Just because it happens to hit 1 particular segment of the population harder than others doesn’t make it less real. 80% women/20% men. Researchers are stupid and don’t consider it starts at Puberty with the first hormone shift, it’s minor at that stage, till a woman hits Peri-Menopause, going full blown at Menopause either natural or Surgical. Every Pregnancy hormone shift also effects FMS.
Duchenes MD which is the worse of the 7 forms of MD, is a Male disease, but it is passed on by the Female though and skips generations.
Think Breast Cancer is strictly a female gene passed disease, think again. When it is in the Male gene pool it is passed on to that man’s daughters and they then pass it on skipping some hitting other females in the same family.
Some diseases do Discriminate according to sex. There are over 1,000 rare Autoimmunes and they hit one sex over the other more. Some are more Equal opportunity diseases. Chron’s is 1 that doesn’t discriminate.
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