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Scientists find way to force cancer cells to die of old age
The Daily Telegraph ^ | March 18, 2010 | Correspondents in Chicago

Posted on 03/18/2010 12:47:46 AM PDT by myknowledge

INSTEAD of killing off cancer cells with toxic drugs, scientists have discovered a molecular pathway that forces them to grow old and die.

Cancer cells spread and grow because they can divide indefinitely.

But a study in mice showed that blocking a cancer-causing gene called Skp2 forced cancer cells to go through an aging process known as senescence - the same process involved in ridding the body of cells damaged by sunlight.

If you block Skp2 in cancer cells, this process is triggered, Pier Paolo Pandolfi of Harvard Medical School in Boston and colleagues reported in the journal Nature.

(Excerpt) Read more at dailytelegraph.com.au ...


TOPICS: Health/Medicine; Science
KEYWORDS: cancer; cancercells; cancertreatment; health; medicine; research; science; skp2
This could be a stepping stone to a cancer cure. Might save a helluva lot of lives in the long run.
1 posted on 03/18/2010 12:47:47 AM PDT by myknowledge
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To: myknowledge

Make it so! :-)


2 posted on 03/18/2010 12:55:18 AM PDT by TigersEye (It's the Marxism, stupid! ... And they call themselves Progressives.)
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To: myknowledge

Selenium has a similar effect, no more than 400mcg/day.


3 posted on 03/18/2010 1:12:38 AM PDT by PeaceBeWithYou (De Oppresso Liber! (50 million and counting in Afganistan and Iraq))
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To: myknowledge

So long as DNA can mutate, cancer will always be there.


4 posted on 03/18/2010 1:17:42 AM PDT by James C. Bennett
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To: neverdem

Very interesting...


5 posted on 03/18/2010 1:26:31 AM PDT by djf (I think "The stuff of life" is not "stuff". But "stuff" ain't bad!!)
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To: myknowledge

Too bad socialized medicine will stop all advancements in medicine.


6 posted on 03/18/2010 7:30:01 AM PDT by crosshairs
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To: crosshairs

7 posted on 03/18/2010 7:39:36 AM PDT by myknowledge (F-22 Raptor: World's Largest Distributor of Sukhoi parts!)
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To: PeaceBeWithYou
Let's hope Obamacare doesn't stop the research ... but I'm afraid it will

KNOXVILLE, Tenn.--(BUSINESS WIRE)--Provectus Pharmaceuticals, Inc. (OTC BB: PVCT - News), .....announced that at the Seventh International Symposium on Melanoma and Other Cutaneous Malignancies on March 12, 2010, commented on the involvement of the immune system in response to PV-10 therapy and its role in the “bystander effect” in treating metastatic melanoma. Dr. Agarwala’s presentation, entitled “Chemoablation in Melanoma: An Update,” was given in the session entitled “Unique Approaches to Melanoma Therapy.”

Dr. Agarwala, Chief, Medical Oncology and Hematology at St. Luke’s Hospital and Health Network in Bethlehem, PA, and Principal Investigator for Provectus’s Phase 2 PV-10 trial site at St. Luke’s, noted, “PV-10 is of particular interest to me as an oncologist because it appears to recruit immune cells to the ablation site, leading to the potential of a systemic benefit. Efficacy data from Phase 1 and from the current Phase 2 study demonstrate a close correlation between objective response in treated lesions and response in uninjected lesions. Survival data from both studies further support a conclusion that patients that respond well to PV-10 respond well overall.”

.

8 posted on 03/18/2010 8:33:47 AM PDT by Elle Bee
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To: AdmSmith; Berosus; bigheadfred; Convert from ECUSA; dervish; Ernest_at_the_Beach; Fred Nerks; ...

That’ll teach the bastards.

Thanks myknowledge.


9 posted on 03/18/2010 3:37:20 PM PDT by SunkenCiv (http://themagicnegro.com/)
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To: PeaceBeWithYou
Retinoic acid (Vitamin A) induces apoptosis as well.
10 posted on 03/19/2010 2:38:53 PM PDT by AdmSmith
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