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Genome-Wide Analysis of Single Nucleotide Polymorphisms Uncovers Population Structure in No. Europe
PLoS ONE ^ | October 24, 2008 | Salmela E, Lappalainen T, Fransson I, Andersen PM, Dahlman-Wright K, et al.

Posted on 10/30/2008 2:00:48 PM PDT by SunkenCiv

Principal Findings
In this study, we analysed almost 250,000 SNPs from a total of 945 samples from Eastern and Western Finland, Sweden, Northern Germany and Great Britain complemented with HapMap data. Small but statistically significant differences were observed between the European populations (FST = 0.0040, p<10-4), also between Eastern and Western Finland (FST = 0.0032, p<10-3). The latter indicated the existence of a relatively strong autosomal substructure within the country, similar to that observed earlier with smaller numbers of markers. The Germans and British were less differentiated than the Swedes, Western Finns and especially the Eastern Finns who also showed other signs of genetic drift. This is likely caused by the later founding of the northern populations, together with subsequent founder and bottleneck effects, and a smaller population size. Furthermore, our data suggest a small eastern contribution among the Finns, consistent with the historical and linguistic background of the population.
Significance
Our results warn against a priori assumptions of homogeneity among Finns and other seemingly isolated populations. Thus, in association studies in such populations, additional caution for population structure may be necessary. Our results illustrate that population history is often important for patterns of genetic variation, and that the analysis of hundreds of thousands of SNPs provides high resolution also for population genetics.

(Excerpt) Read more at plosone.org ...


TOPICS: History; Science; Travel
KEYWORDS: dna; emptydna; finns; genetics; godsgravesglyphs; mtdna
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1 posted on 10/30/2008 2:00:49 PM PDT by SunkenCiv
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To: martin_fierro; StayAt HomeMother; Ernest_at_the_Beach; 1ofmanyfree; 21twelve; 24Karet; ...

· join list or digest · view topics · view or post blog · bookmark · post a topic ·

 
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To all -- please ping me to other topics which are appropriate for the GGG list.
GGG managers are SunkenCiv, StayAt HomeMother, and Ernest_at_the_Beach
 

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2 posted on 10/30/2008 2:01:27 PM PDT by SunkenCiv (https://secure.freerepublic.com/donate/_______Profile finally updated Saturday, October 11, 2008 !!!)
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To: SunkenCiv

Oh my head hurts now LOL

this is really interesting! Debunking myths about geneology lol


3 posted on 10/30/2008 2:04:13 PM PDT by Danae (Obama = Trickle up Poverty. Don't like it, get ready to be"reeducated" into it if he is elected.)
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To: SunkenCiv

Bump for later


4 posted on 10/30/2008 2:06:40 PM PDT by Oratam
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To: Danae

The use of DNA as a tool in genealogy has been around since 2000. I manage a number of DNA projects at www.familytreedna.com

This article is more for the use of DNA in Anthropology.


5 posted on 10/30/2008 2:09:19 PM PDT by DGodbey
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To: SunkenCiv; martin_fierro; StayAt HomeMother; Ernest_at_the_Beach; 1ofmanyfree; 21twelve; 24Karet
Thank God your post arrived in time!

I was just about to serve lutefisk to a party of Finns. Since these genetic markers mean they don't have the requisite digestive enzyme, lutefisk could have killed them faster than a logging accident! Now we can just skip to the akvavit without the awkward formalities.

This still doesn't explain why Finnish, Hungarian, and Korean are related languages.

6 posted on 10/30/2008 2:10:36 PM PDT by Kenny Bunk (Marxist Muslim Cousin Odinga burned Christians in their churches. Obama bought him the gas.)
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To: SunkenCiv

YEAH!

Take THAT!

In your Face with your a priori assumptions!

That’l larn ya!

It’s late!


7 posted on 10/30/2008 2:12:16 PM PDT by petro45acp (NO good endeavor survives an excess of "adult supervision" (read bureaucracy)!)
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To: Kenny Bunk

8 posted on 10/30/2008 2:34:46 PM PDT by JoeProBono
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To: SunkenCiv

I’d love to see a similar study on the Basques. Their native language is among the most unique on the planet.


9 posted on 10/30/2008 2:43:43 PM PDT by gorush (History repeats itself because human nature is static)
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To: Kenny Bunk
This still doesn't explain why Finnish, Hungarian, and Korean are related languages.

The Finnish and Hungarian (Magyar) languages are Hunnish languages, the connection to Korean is more conjectual. If we assume that Finnish speakers arrived in the area some centuries BC (see Tacitus' Germania, they could have dominated the folks there before, this would explain the quote: 'our data suggest a small eastern contribution among the Finns, consistent with the historical and linguistic background of the population.'

10 posted on 10/30/2008 2:58:32 PM PDT by Lucius Cornelius Sulla (White Trash for Sarah!)
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To: Kenny Bunk

Finns may eat lutefisk, but it is still a nasty suggestion.


11 posted on 10/30/2008 3:00:12 PM PDT by Lucius Cornelius Sulla (White Trash for Sarah!)
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To: gorush

And the Basque I know are some of the most beautiful people ever. Too bad I’m alergic to sheep.


12 posted on 10/30/2008 3:44:00 PM PDT by Battle Axe (Repent for the coming of the Lord is nigh!)
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To: Coyoteman; Soliton

Like, *PING*, dudes.


13 posted on 10/30/2008 4:53:27 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: AdmSmith; AnalogReigns; Cacique; caryatid; Celtjew Libertarian; CobaltBlue; concentric circles; ...
Genetic
Genealogy
Send FReepmail if you want on/off GGP list
Marty = Paternal Haplogroup O(2?)(M175)
Maternal Haplogroup H
GG LINKS:
African Ancestry
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The List of Ping Lists

14 posted on 10/30/2008 6:13:39 PM PDT by martin_fierro (< |:)~)
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To: All

Wow! Who knew this topic would be such a hit? :’)


15 posted on 10/31/2008 6:17:27 AM PDT by SunkenCiv (https://secure.freerepublic.com/donate/_______Profile finally updated Saturday, October 11, 2008 !!!)
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To: martin_fierro

I tried to make sense of it all in the first reading, but will come back later after another cup of coffee. Thanks for the ping!


16 posted on 10/31/2008 7:16:58 AM PDT by voiceinthewind
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To: Kenny Bunk

> This still doesn’t explain why Finnish, Hungarian, and Korean are related languages <

Because after the Huns occupied Korea ca. 500 AD, they took a lot of Korean war brides back home to Hungary.

Therefore, with many mothers in Hungary speaking Korean to their children, the Korean language gradually infiltrated itself into the Hungarian national consciousness.

(Moreover, although the Finns didn’t occupy Korea, a lot of them worked there in the PX for the Huns, and they also took a lot of Korean brides back home with them.)


17 posted on 10/31/2008 8:07:38 AM PDT by Hawthorn
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To: Hawthorn; Lucius Cornelius Sulla
Therefore, with many mothers in Hungary speaking Korean to their children, the Korean language gradually infiltrated itself into the Hungarian national consciousness.

Gosh, thanks for clearing that up, Sully,Haw!

Haw, A 5-CD copy of my monograph on "The Striking Similarity between Kim-Chi, Goulash, Obama's Foreign Policy Thoughts, and Finnish Drinking Games," with Spanish subtítulos, is winging its way to you as we speak.

Sully, you have qualified for a trip for two to the justly famed St. Olaf's Festival in Norway, Maine. As soon as your cheque clears, we shall issue the necessary travel vouchers and border-crossing documents.

18 posted on 10/31/2008 11:19:13 AM PDT by Kenny Bunk (Marxist Muslim Cousin Odinga burned Christians in their churches. Obama bought him the gas.)
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To: JoeProBono
Great News pING!

You have qualified for Second Prize, which is trip for three to the Norway, Maine St.Olaf Festival. Sully will be eating his heart out. (Which prolly tastes a bit better than you-know-what.)

19 posted on 10/31/2008 12:29:38 PM PDT by Kenny Bunk (Marxist Muslim Cousin Odinga burned Christians in their churches. Obama bought him the gas.)
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To: Battle Axe

“Too bad I’m alergic to sheep.”

Did you know that Anthrax is one of the oldest recorded diseases of grazing animals such as sheep and cattle and is believed to be the Sixth Plague?

Why of course you did :-)


20 posted on 10/31/2008 2:07:27 PM PDT by JoeProBono
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