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Scientists Reverse Type 1 Diabetes for the First Time
Greek Reporter ^ | November 2, 2024 | Abdul Moeed

Posted on 11/01/2024 4:02:55 PM PDT by nickcarraway

Scientists in China have taken a major step forward in treating type 1 diabetes. They used a woman’s own fat cells and changed them to work like special cells in the pancreas, the organ that makes insulin. This new approach, to reverse type 1 diabetes, helped her body make insulin again, reducing her need for daily injections.

This achievement builds on other research suggesting that transformed cells could one day help people manage or even overcome diabetes. Remarkably, a year after the procedure, the patient still doesn’t need insulin shots.

Dr. Kevan Herold, an expert in medicine and immunology from Yale School of Medicine, called the findings “very exciting.” Although he was not part of the study, Dr. Herold noted the progress brings hope for better diabetes treatments in the future.

Insulin helps sugar leave the blood

Insulin acts like a key, helping sugar leave the blood and enter cells to provide energy. In type 1 diabetes, the immune system attacks and destroys the cells that make insulin. These cells are found in small clusters, called islets, within the pancreas.

Without insulin, cells can’t get the energy they need, causing blood sugar levels to rise. In severe cases, the body starts producing acidic substances called ketones as it tries to find alternative fuel. If left unchecked, this process can be life-threatening.

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In a new study published on Oct. 31 in the journal Cell, scientists used a patient’s own fat cells to find a potential solution. They chemically treated these cells, turning them into “pluripotent” stem cells, meaning they have the ability to become almost any type of cell in the body.

Once the scientists changed the fat cells back to a flexible state, they used chemicals to guide them into becoming islet cells, which can produce insulin. These new cells were then placed in the patient’s abdomen.

Insulin injections no longer needed 75 days after the transplant

Before this experimental procedure, the patient found it difficult to keep her blood sugar within a healthy range, managing to do so less than half the time, according to study lead author Hongkui Deng from the Peking-Tsinghua Center for Life Sciences at Peking University.

However, after receiving the cell transplant, her time in the healthy range increased to over 98%, Deng reported to Live Science in an email. Just 75 days after the transplant, the patient no longer needed insulin injections to manage her blood sugar.

“The rapidity with which the patient showed reversal of diabetes and achieved insulin independence after transplantation was surprising,” Deng said. “This finding suggested remarkable potential of this therapeutic strategy.”


TOPICS: Business/Economy; Health/Medicine; Science
KEYWORDS: adultstemcells; diabetes; science; type1; type1diabetes

1 posted on 11/01/2024 4:02:55 PM PDT by nickcarraway
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To: ConservativeMind

Ping


2 posted on 11/01/2024 4:04:18 PM PDT by nickcarraway
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To: nickcarraway

This will be very useful.


3 posted on 11/01/2024 4:06:35 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: nickcarraway

That would be lovely. I hope this works.


4 posted on 11/01/2024 4:09:25 PM PDT by Beowulf9
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To: ConservativeMind

“This will be very useful.”

Except that it’s probably not nearly as useful to Type 2’s, as their problem (at least in the earlier stages) is Insulin Resistance, as their bodies are pumping out Insulin like mad. But then, yes, the pancreas does burn out, but they’ll still have far too much Insulin in their bodies, which causes its own set of major problems...whether they’re shooting it or found other cells to make it.

Obviously the only way to take care of both blood sugar levels and Insulin levels is to go on a Proper Human Diet.


5 posted on 11/01/2024 4:23:52 PM PDT by BobL
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To: nickcarraway

See, organ harvesting has its benefits.


6 posted on 11/01/2024 4:24:07 PM PDT by AlmaKing
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To: nickcarraway

https://news.mit.edu/2023/implantable-device-enable-injection-free-control-diabetes-0918


7 posted on 11/01/2024 4:32:16 PM PDT by Honorary Serb (Kosovo is Serbia! Free Srpska! Abolish ICTY!)
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To: nickcarraway

ttps://news.harvard.edu/gazette/story/2021/11/harvard-diabetes-researcher-details-science-behind-potential-breakthrough/


8 posted on 11/01/2024 4:33:48 PM PDT by Honorary Serb (Kosovo is Serbia! Free Srpska! Abolish ICTY!)
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To: nickcarraway

https://news.harvard.edu/gazette/story/2021/11/harvard-diabetes-researcher-details-science-behind-potential-breakthrough/


9 posted on 11/01/2024 4:34:38 PM PDT by Honorary Serb (Kosovo is Serbia! Free Srpska! Abolish ICTY!)
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To: nickcarraway

FDA will approve it here in 50 years or so.


10 posted on 11/01/2024 5:16:44 PM PDT by Bonemaker (invictus maneo)
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To: BobL

There is no diet that can relieve Type 1 diabetics of the need for regular insulin injections. Type 1 and Type 2 are different enough that they shouldn’t even have the same disease name.


11 posted on 11/01/2024 5:36:45 PM PDT by Calvin Cooledge
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To: Calvin Cooledge

“There is no diet that can relieve Type 1 diabetics of the need for regular insulin injections. Type 1 and Type 2 are different enough that they shouldn’t even have the same disease name.”

Agree, totally. Diet alone was used to treat Type 1, prior to Insulin being discovered...and people lived a bit longer, but all died very early.


12 posted on 11/01/2024 6:08:36 PM PDT by BobL
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To: null and void; aragorn; EnigmaticAnomaly; kalee; Kale; AZ .44 MAG; Baynative; bgill; bitt; ...

P


13 posted on 11/01/2024 6:59:15 PM PDT by bitt (<img src=' 'width=30%>)
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To: nickcarraway; bitt
***They chemically treated these cells, turning them into “pluripotent” stem cells, meaning they have the ability to become almost any type of cell in the body.

Once the scientists changed the fat cells back to a flexible state, they used chemicals to guide them into becoming islet cells, which can produce insulin. These new cells were then placed in the patient’s abdomen***

I am skeptical... and a bit unsettled. The idea of turning a fat cell into a 'universal' stem cell and then 'guiding' them into any needed cell in the body is a bit science fiction. Not that I don't trust the Chinese - but I don't trust the Chinese.

Then there is this story of the Chinese trying to create 'a better human being' - a 'super' being, the perfect soldier, the more perfect human. Isn't that what Satan said in order to tempt Eve in the Garden into destroying herself and mankind❓ What are the side effects of this 'cloning' experiment?

Are we turning (God's) creation on its ear?❓

14 posted on 11/01/2024 7:25:10 PM PDT by Bob Ireland (The Democrap Party is the enemy of freedom.They use all the seductions and deceits of the Bolshevics)
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To: BobL

Type 2 is easily treated and cured.

I can’t believe in the age of information, people still don’t know it.


15 posted on 11/01/2024 7:26:14 PM PDT by Salvavida
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To: Salvavida

“Type 2 is easily treated and cured. I can’t believe in the age of information, people still don’t know it.”

Oh, they know, they all know, but they’re not free to disclose it, if they want to keep their jobs and not be sued.


16 posted on 11/01/2024 7:46:12 PM PDT by BobL
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To: BobL

Joel Wallach has been preaching the cure for 50 years. He got too popular, so they didn’t kill him.

Frank Suarez started preaching to the hispanic community, and he was promptly thrown off of a building.


17 posted on 11/01/2024 9:19:57 PM PDT by Salvavida
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said, "Insulin helps sugar leave the blood"

So does Vit B3 Niacin (Blush) and Raises HDL
https://www.nature.com/articles/nrendo.2011.235
https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/niacin/art-20046208

Effectiveness of niacin supplementation for patients with type 2 diabetes A meta-analysis of randomized controlled trials
https://journals.lww.com/md-journal/fulltext/2020/07170/effectiveness_of_niacin_supplementation_for.94.aspx
18 posted on 11/01/2024 11:26:39 PM PDT by Steve Van Doorn
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