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Frequent inbreeding may have caused skeletal abnormalities in early humans
ScienceMag.org ^ | Nov 5, 2018 | Michael Price

Posted on 11/06/2018 12:24:18 PM PST by ETL

Early humans faced countless challenges as they fanned out of Africa: icy conditions, saber-tooth cats, and, according to a new study of ancient skeletons, an unusually high number of birth defects, both debilitating and relatively inconsequential. It’s unclear why such abnormalities seem to be so common, but scientists say one strong possibility is rampant inbreeding among small hunter-gatherer groups.

“This paper represents a valuable compilation,” says Vincenzo Formicola, an anthropologist at the University of Pisa in Italy who wasn’t involved in the new work. “Many cases reported in the list were unknown to me and, I assume, to many people working in the field.”

Many human fossils from the Pleistocene (roughly 2.5 million B.C.E. to 9700 B.C.E.) have unusual features. For example, femur bones with abnormal bowing have been found from China to the Czech Republic. The skull of a toddler found in the Qafzeh cave in Israel had a swollen braincase consistent with hydrocephalus, a condition in which fluid floods the skull. And a fossilized man in Liguria in Italy had a bowed right upper arm bone but a normal left one.

By and large, these were viewed as one-off curiosities. But Erik Trinkaus, a paleoanthropologist at Washington University in St. Louis, Missouri, noticed a pattern: These skeletal deformations seemed to be suspiciously common in the fossil record.

So Trinkaus did the math. He assembled data on 66 individuals with skeletal abnormalities mostly dating to the past 200,000 years. The fossils, most from young adults, were found in sites scattered throughout the Middle East and Eurasia and represent several different species of Homo. Trinkaus then researched how common their conditions are in modern human populations.

He found that about two-thirds of the ancient abnormalities occur in less than 1% of modern humans. Another dozen or so didn’t match any known modern developmental disorder. Trinkaus ran the odds that archaeologists would have uncovered so many ancient abnormalities by chance, and he found that it would have been a “truly, vanishingly small probability.” That suggests, he reports today in the Proceedings of the National Academy of Sciences, that early humans faced some cultural or environmental pressure that led to so many deformities.

One possibility, previously proposed by other researchers: Ancient people with skeletal deformities might have been seen as shamans and given careful burials, making their bodies more likely to be preserved and later found. Another: Pregnant mothers didn’t get enough of the right nutrients, leading to more skeletal disorders. But Trinkaus notes that, whereas some skeletal disorders like rickets affect the whole body, many skeletons were found with deformities on only one side of the body. He also says many fossils in his analysis show no evidence of special rites.

However, several bodies show abnormalities consistent with known genetic mutations, and multiple individuals from at least one site exhibited several different conditions, suggesting the people might be related. It’s thought that most human populations at the time were small and isolated, Trinkaus says. In those conditions, inbreeding can lead to widespread harmful genetic mutations.

Evidence of low genetic diversity among Pleistocene humans based on ancient DNA analysis also supports this hypothesis, says Hallie Buckley, a bioarchaeologist at the University of Otago in Dunedin, New Zealand. “Of all the arguments put forward … this seems the most likely explanation.”

Further analysis of ancient DNA at these sites might confirm inbreeding, but prepping samples for such investigations often means destroying them. “Ancient DNA has become increasingly viewed as a ‘magic bullet’ to shoot at any question about past human populations, but that may not always be justified,” Buckley says.

Siân Halcrow, Buckley’s colleague at the University of Otago, says that although she appreciates Trinkaus’s thorough cataloging, his paper has several weaknesses, most notably in its estimates of how common these abnormalities are in modern people—and how common they used to be. It would be better to compare the ancient rates to later populations in prehistory or early historic populations, she says, but unfortunately those data don’t exist.

No matter the cause, many of the deformities would have been debilitating. The fact that so many survived past childhood suggests early humans must have offered each other social support and medical knowhow, Trinkaus says. For example, although hydrocephaly is rarely a death sentence thanks to modern treatment, it can easily be fatal if left untreated. “The Qefzeh child with hydrocephaly lived until about 3 or 4 years old. When you consider it lived 100,000 years ago, that’s pretty amazing.”


TOPICS: Chit/Chat; Health/Medicine; History; Science
KEYWORDS: bone; godsgravesglyphs; helixmakemineadouble; hydrocephalus; hydrocephaly; pleistocene; skeletons
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To: AnalogReigns

I heard a talk a long time ago about brother-sister marriages in ancient Egypt (I think from the period when it was part of the Roman Empire). The speaker argued that the harmful genes producing defects would be eliminated from the population because of the close relationships—two carriers would marry and produce non-viable children or badly deformed children and the bad gene would gradually disappear from the population.


41 posted on 11/06/2018 1:11:40 PM PST by Verginius Rufus
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To: AnalogReigns

That explains the British Monarchy.


42 posted on 11/06/2018 1:19:48 PM PST by dhs12345
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To: ETL

Is that a real quote???


43 posted on 11/06/2018 1:21:50 PM PST by Campion ((marine dad))
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To: ETL

Went down hill after that...


44 posted on 11/06/2018 1:34:16 PM PST by dhs12345
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To: Campion
Is that a real quote???

According to the following site, no.

https://www.truthorfiction.com/rep-sheila-jackson-lee-blames-washington-derailment-trumps-hatred-african-americans-fiction/

I'll ask the mods to remove the post. Sure seemed like something the idiot would say.

45 posted on 11/06/2018 1:34:45 PM PST by ETL (Obama-Hillary, REAL Russia collusion! Uranium-One Deal, Missile Defense, Iran Deal, Nukes: Click ETL)
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To: Campion

Bumped United passenger fires back at Rep. Jackson Lee’s racism charge, airline

Barnini Chakraborty, Judson Berger, | Fox News
Dec 2017

A United passenger whose first-class seat on a recent flight from Houston to D.C. was given to Rep. Sheila Jackson Lee is firing back at the Democratic congresswoman’s accusations of racism – while challenging the airline’s account of the incident.

Jean-Marie Simon, an attorney and private school teacher, became the latest face of airline passenger woes when she detailed on Facebook and later to the news media how she lost her seat to the Texas lawmaker.

But despite a statement from United seeking to explain the switch-out, she’s not giving up the fight. And the congresswoman’s response – essentially claiming Simon made a scene because Jackson Lee, as an African-American woman, is an “easy target” – did not calm the waters.

Simon, in an interview with Fox News, rejected the racism allegation.

“That could have been Donald Duck in my seat,” Simon, a Democrat, told Fox News on Thursday. “I could not see who had boarded the flight. I didn’t even know who she was.”

Simon originally accused United of bumping her from her first-class seat on a Dec. 18 flight in order to accommodate the Texas congresswoman.

At first, Simon didn’t know who was in her seat as she argued at the gate. United eventually gave her a $500 voucher and reseated her in the economy plus section. In her original Facebook post, Simon said another Texas congressman then informed her a fellow member of the delegation was in her seat, and “regularly does this” to passengers. ...”

more at link

https://www.foxnews.com/politics/bumped-united-passenger-fires-back-at-rep-jackson-lees-racism-charge-airline


46 posted on 11/06/2018 1:37:22 PM PST by ETL (Obama-Hillary, REAL Russia collusion! Uranium-One Deal, Missile Defense, Iran Deal, Nukes: Click ETL)
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To: Calvin Locke
Iceland as well.
47 posted on 11/06/2018 1:38:28 PM PST by Harmless Teddy Bear (Somewhere there's danger, somewhere there's injustice, and somewhere else the tea is getting cold.)
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To: ETL
Explains Ole Miss fans.


48 posted on 11/06/2018 1:45:38 PM PST by MuttTheHoople (GOP- 65 House and 12 Senate seat pickups in November)
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To: Jewbacca

.
Nothing “oral” was given at sinai, that is Pharisee blasphemy. That idea came in the 2nd temple period.


49 posted on 11/06/2018 2:04:53 PM PST by editor-surveyor (Freepers: Not as smart as I'd hoped they'd be)
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To: ETL

Don’t mind me - I just came here for the pictures (and Freepers do not disappoint).


50 posted on 11/06/2018 2:07:56 PM PST by Stosh
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To: editor-surveyor

Sorry, I didn’t know you were a mental defective.

I won’t bother any further.


51 posted on 11/06/2018 2:22:27 PM PST by Jewbacca (The residents of Iroquois territory may not determine whether Jews may live in Jerusalem)
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To: Jewbacca

Bwwaaah! Made my day, great post!


52 posted on 11/06/2018 2:40:35 PM PST by nicollo (I said no!)
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To: ExTexasRedhead

Ha ha!
They outbred to Neanderthals


53 posted on 11/06/2018 2:51:59 PM PST by ZULU (Jeff Sessions should be tried for sedition.)
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To: Scythian_Reborn
But what about Ned Beatty ?

OMG that made me laugh!

54 posted on 11/06/2018 2:53:24 PM PST by PistolPaknMama
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To: AnalogReigns

I think that was only Egyptian royalty.


55 posted on 11/06/2018 3:14:00 PM PST by Reily
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To: Jewbacca

.
Clinging to the circus, huh?


56 posted on 11/06/2018 4:38:20 PM PST by editor-surveyor (Freepers: Not as smart as I'd hoped they'd be)
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To: ETL

.
6000 years ago more or less.

Time itself didn’t exist before that.


57 posted on 11/06/2018 4:45:02 PM PST by editor-surveyor (Freepers: Not as smart as I'd hoped they'd be)
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To: ExTexasRedhead

Exactly!


58 posted on 11/07/2018 2:03:20 AM PST by sheik yerbouty ( Make America and the world a jihad free zone!)
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To: Jewbacca

The face that sank a thousand ships..


59 posted on 11/07/2018 2:04:10 AM PST by sheik yerbouty ( Make America and the world a jihad free zone!)
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To: Reily

Incest between brother & sister was especially Egyptian royalty. Incest of various kinds though, was common in other cultures as well. I believe it was the Jews who first made laws against it.

The Canaanite peoples the Hebrews displaced actually worshiped brother & sister gods which were also husband and wife....


60 posted on 11/08/2018 10:34:59 AM PST by AnalogReigns (Real life is ANALOG...)
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