US Ebola Death: Antivirals Submitted by admin on Wed, 10/08/2014 - 13:19 The first U.S. Ebola patient, Thomas Eric Duncan, has died despite being administered the experimental nucleoside-type antiviral pro-drug Brincidofovir. How is this possible? Well , the first problem is that Duncan was not treated until it was far too late for antiviral therapy to work. Let's take this opportunity to look at some nucleoside antivirals, incuding the drug that was administered to Mr. Duncan in Dallas, TX (Brincidofovir).The first thing to know is remember Brincidofovir and Cidofovir were developed to work against dsDNA Viruses, though Ebola is a...