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Keyword: wza

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  • Antibiotic research hits a sweet spot

    07/04/2013 10:28:37 PM PDT · by neverdem · 13 replies
    Chemistry World ^ | 1 July 2013 | James Urquhart
    The cyclodextrin can block the Wza pore and prevent E. coli from suiting up © NPGUK researchers have found a way to weaken the molecular armour of Escherichia coli to allow the host's immune system to attack and kill the pathogen. The discovery could pave the way for new antibiotic drugs that make it harder for pathogenic bacteria to develop resistance.Antibiotic resistance is one of the world's most pressing public health concerns. As bacteria quickly mutate to become resistant, the effectiveness of antibiotic drugs aimed at current targets are diminishing. An alarming trend in recent years is the emergence of...