Free Republic

How would you summarize your study? Cisplatin is a chemotherapy drug used globally for the treatment of several cancers; however, it is also highly toxic to the kidneys. Beyond general supportive measures, there is minimal data from clinical trials regarding preventive treatments for cisplatin-associated kidney damage. Animal studies suggest magnesium may help the kidneys excrete cisplatin in the urine, thereby protecting the kidneys from damage. However, data from larger studies in humans is lacking. What question were you investigating? We examined whether receipt of IV magnesium on the same day as the first dose of IV cisplatin was associated with...

Agency says radioactive materials recovered in home of man allegedly slain by his wife ...BELFAST, Maine — James G. Cummings, who police say was shot to death by his wife two months ago, allegedly had a cache of radioactive materials in his home suitable for building a “dirty bomb.” According to an FBI field intelligence report from the Washington Regional Threat and Analysis Center posted online by WikiLeaks, an organization that posts leaked documents, an investigation into the case revealed that radioactive materials were removed from Cummings’ home after his shooting death on Dec. 9 It says that four 1-gallon...

Bacillus subtilis bacteria with green fluorescence indicating a lack of magnesium. (Ashley Moon, Süel Lab, UC San Diego) New tactics in controlling infection are sorely needed, with antibiotic-resistant bacteria expected to claim as many as 2 million lives each year by 2050. US and Spanish researchers have now discovered at least some bacteria pay a steep price for their resistance – a cost that we may be able to exploit to fight infection. "We discovered an Achilles heel of antibiotic-resistant bacteria," says molecular biologist Gürol Süel from the University of California, San Diego. "We can take advantage of this cost...

Lithium can now be extracted directly from previously untapped extreme environments. The demand for lithium, essential for powering sustainable technologies, is rising quickly, yet current methods leave up to 75% of the world’s lithium-rich saltwater sources inaccessible. With some predicting global lithium supply could fall short of demand as early as 2025, the innovative technology – EDTA-aided loose nanofiltration (EALNF) – sets a new standard in lithium processing. The technology uniquely extracts both lithium and magnesium simultaneously, unlike traditional methods that treat magnesium salts as waste, making it smarter, faster and more sustainable. The work, co-led by Dr Zhikao Li,...

A study has identified why a diet rich in magnesium is important for our health, reducing the risk of DNA damage and chronic degenerative disorders. Scientists measured blood samples from 172 middle aged adults, finding a strong link between low magnesium levels and high amounts of a genotoxic amino acid called homocysteine. This toxic combination damages the body's genes, making people more susceptible to Alzheimer's and Parkinson's disease, gastrointestinal diseases, a range of cancers, and diabetes. Whole grains, dark green leafy vegetables, nuts, beans and dark chocolate are all magnesium-rich foods, which help the body produce energy, build teeth and...

One in five Americans regularly reach for vitamin D supplements, yet most are unaware that they’re taking not just a vitamin - but a hormone.While renowned for bolstering bone strength and immune health, vitamin D’s story is not straightforward. A blend of myth and established science invites a closer look into its true nature and impact.Vitamin D: Understanding Its Dual RoleVitamin D stands apart in the world of nutrients. It’s a sun-sourced substance acting as both a nutrient and a hormone. This dual role is significant, as hormones, which orchestrate many bodily functions, aren’t typically taken as supplements like vitamins.Endocrinologist...

Magnesium is a mineral critical to a wide range of biological functions, and a new study takes aim at how it's transported to address cardiac dysfunction and other diseases, opening new possibilities for treatment. The study charts a new course in explaining how a novel protein called ERMA—a long-time mystery—functions as a precision-engineered pump in guiding magnesium. The investigation reveals how disruptions in ERMA's function can lead to significant disturbances in how heart cells manage calcium, crucial for the rhythmic contractions of the heart muscle. These imbalances can lead to cardiac dysfunctions, particularly affecting the heart's relaxation phase and its...

Using patient data from six major U.S. cancer centers, researchers developed a risk prediction model for moderate-to-severe kidney injury after receiving the chemotherapy drug cisplatin in the largest, first generalizable study of its kind Cisplatin is a highly effective chemotherapy that has been used to treat cancer for decades, but it can cause kidney injury that can potentially lead to the discontinuation of life-saving cancer treatments. Investigators developed a comprehensive tool to predict which patients are at highest risk of moderate-to-severe kidney injury after cisplatin. They found the highest-risk patients had as much as a 20-fold higher risk of developing...

For military veterans, many of the deepest wounds of war are invisible: Traumatic brain injuries resulting from head trauma or blast explosions. Now, researchers have discovered that the plant-based psychoactive drug ibogaine, when combined with magnesium to protect the heart, safely and effectively reduces PTSD, anxiety and depression and improves functioning in veterans with TBI. Ibogaine is found in the roots of the African shrub iboga. Since 1970, ibogaine has been designated as a Schedule I drug, preventing its use within the U.S. Before the treatment, researchers gauged the participants' levels of PTSD. Participants then traveled to a clinic in...

Chemical Elements in a Distant Gas Cloud This artist’s impression shows a distant gas cloud that contains different chemical elements, illustrated here with schematic representations of various atoms. Using ESO’s Very Large Telescope, astronomers have detected three distant gas clouds whose chemical composition matches what we expect from the explosions of the first stars that appeared in the Universe. These early stars can be studied indirectly by analyzing the chemical elements they dispersed into the surrounding environment after they died in supernova explosions. The three distant gas clouds detected in this study are rich in carbon, oxygen, and magnesium, but...

More magnesium in our daily diet leads to better brain health as we age, according to scientists. The researchers say increased intake of magnesium-rich foods such as spinach and nuts could also help reduce the risk of dementia, which is the seventh biggest killer globally. The study of more than 6,000 cognitively healthy participants in the United Kingdom aged 40 to 73 found people who consume more than 550 milligrams of magnesium each day have a brain age that is approximately one year younger by the time they reach 55 compared with someone with a normal magnesium intake of about...

A program to increase the use of magnesium sulfate, a £1 injection that helps prevent cerebral palsy in premature babies, is effective according to a National Institute for Health and Care Research (NIHR) evaluation. The findings, led by researchers at the University of Bristol, are published in the Archives of Disease in Childhood—Fetal and Neonatal Edition. Premature birth is the main cause of brain injury and cerebral palsy in babies. Evidence shows that babies can be protected from brain injury by giving magnesium sulfate to women who are at risk of premature birth. This reduces the risk of cerebral palsy...

Scientists Confirm Institute of Medicine Recommendation for Vitamin D Intake Was Miscalculated and Is Far Too Low Released: 17-Mar-2015 10:05 AM EDTSource Newsroom: Creighton University more news from this source Contact InformationAvailable for logged-in reporters onlyCitationsNutrients 2014Newswise — SAN DIEGO, CA (March 16, 2015) - Researchers at UC San Diego and Creighton University have challenged the intake of vitamin D recommended by the National Academy of Sciences (NAS) Institute of Medicine (IOM), stating that their Recommended Dietary Allowance (RDA) for vitamin D underestimates the need by a factor of ten.In a letter1 published last week in the journal Nutrients...

NATIONAL CASHEW DAY A favorite snacking and party nut is recognized each year on November 23rd during National Cashew Day. #NationalCashewDay The cashew nut is a seed harvested from the cashew tree. The tree originated in Northeastern Brazil. However, it is now widely grown in tropical climates for its cashew apples and nuts. With leathery leaves arranged spirally, the evergreen cashew tree grows as tall as 32 feet high and often has an irregularly shaped trunk. The flowers are small, starting out pale green then turning reddish, with each one having five slender, acute petals. The largest cashew tree in...

Food With Magnesium Many popular foods contain magnesium, including almonds, avocado, bananas, cashews, dark chocolate, and peanuts. Magnesium is an essential mineral that plays a role in muscle relaxation, blood pressure regulation, and nerve function. Magnesium is also involved in the production of energy from food. That’s why some people call it the “energy mineral.” Despite its importance, not everyone gets enough. Magnesium deficiency is relatively common in Western diets because so many people eat a heavily processed diet low in magnesium. Plus, they eat too few whole grains, nuts, seeds, and leafy green vegetables naturally high in magnesium. According...

At 563 carats, the Star of India is the world’s largest gem-quality blue star sapphire, and is approximately 2 billion years old. (Image credit: D. Finnin/Copyright AMNH) ================================================================== What does the legendary Star of India — a 563-carat star sapphire the size of a golf ball — have in common with a 35-million-year-old petrified redwood slab; a massive cluster of sword-like crystals that looks like it came from "Game of Thrones;" and a 5-ton (4.5-metric ton) stone pillar that can "sing?" You can see all of them, along with 5,000 other amazing stones, in the newly renovated Mignone Hall of...

The level of magnesium in the blood is an important factor in the immune system's ability to tackle pathogens and cancer cells. Researchers from have reported that T cells need a sufficient quantity of magnesium in order to operate efficiently. Their findings may have important implications for cancer patients. Magnesium deficiency is associated with a variety of diseases, such as infections and cancer. Previous studies have shown that cancerous growths spread faster in the bodies of mice when the animals received a low-magnesium diet—and that their defense against flu viruses was also impaired. However, there has so far been little...

A critical element in everything from engines to bodies is in short supply ... Essentially, you can’t make cars without aluminum. You can’t work with aluminum without using magnesium. And as of December, you may not be able to work with magnesium much — if at all. 85% of the world’s supply comes from ... China, ... (which) just ordered 35 of its 50 production facilities to shut down. The remaining 15 have been told to scale back operations by half, leaving production drastically reduced.

Has anyone gotten relief ?How ?

Overheard some lady at a supermarket telling a cashier the reasons she is buying magnesium supplements is to protect her from the jab, supposedly wipe it out in her blood. I checked the web for this claim but nothing turns up. Has anyone heard this? Is this the latest thing from some conspiracy or q-anon podcast? Must be some magnesium supplier made it up to boost sales.