Psychoactive drug ibogaine found to effectively treat traumatic brain injury in special operations military vets (From mild-to-moderate disability to none with ibogaine and magnesium)

Medical Xpress / Stanford University Medical Center / Nature Medicine ^ | Jan. 5, 2024 | Nolan Williams, MD et al

[ConservativeMind]

For military veterans, many of the deepest wounds of war are invisible: Traumatic brain injuries resulting from head trauma or blast explosions.

Now, researchers have discovered that the plant-based psychoactive drug ibogaine, when combined with magnesium to protect the heart, safely and effectively reduces PTSD, anxiety and depression and improves functioning in veterans with TBI.

Ibogaine is found in the roots of the African shrub iboga.

Since 1970, ibogaine has been designated as a Schedule I drug, preventing its use within the U.S.

Before the treatment, researchers gauged the participants' levels of PTSD. Participants then traveled to a clinic in Mexico run by Ambio Life Sciences, where under medical monitoring they received oral ibogaine along with magnesium to help prevent heart complications that have been associated with ibogaine.

At the beginning, participants were experiencing clinically significant levels of disability as measured by the World Health Organization Disability Assessment Scale 2.0. In addition, 23 met the criteria for PTSD, 14 for an anxiety disorder and 15 for alcohol use disorder.

On average, treatment with ibogaine immediately led to significant improvements in functioning, PTSD, depression and anxiety. Moreover, those effects persisted until at least one month after treatment—the endpoint of the study.

Before treatment, the veterans had an average disability rating of 30.2 on the disability assessment scale, equivalent to mild to moderate disability. One month after treatment, that rating improved to 5.1, indicating no disability. Similarly, one month after treatment, participants experienced average reductions of 88% in PTSD symptoms, 87% in depression symptoms and 81% in anxiety symptoms relative to how they were before ibogaine treatment. Formal cognitive testing also revealed improvements in participants' concentration, information processing, memory and impulsivity.

Importantly, there were no serious side effects of ibogaine.

[ConservativeMind]

What’s amazing is that virtually all were left with no disability.

A bit more information is in the linked article. This appears available today, from Amblo Life Services, in Mexico.

[ConservativeMind]

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[Rockingham]

Magnesium stores are primarily intracellular and are especially significant in protecting the heart and brain. Most prominently, magnesium rebuilds and replaces mitochondria in the cells. The mitochondria generate adenosine triphosphate, the energy molecule essential to every cell in the body. There is reason to believe that magnesium deficiency is common and can have a highly detrimental effect on brain function and healing after injury.

[b4me]

why the drug? why not magnesium and other natural things? Body’s aren’t lacking in man made drugs that usually have some unforeseen side effect at some point.

[spankalib]

I went to school with one of ibogaine's proponents:

Dr. Deborah Mash:
https://en.wikipedia.org/wiki/Deborah_Mash

She described it to me at our last reunion...

[Taffini]

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