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I have been engaged in an ongoing dialogue with a physician who works in a major children’s hospital in a blue city. This physician has witnessed firsthand how transgender ideology has captured the medical profession and jeopardized the first commandment of the healing sciences: do no harm. He has now chosen to speak out, on condition of anonymity, because he is alarmed by the sudden corruption of the medical community. His colleagues, many of whom oppose transgender interventions, have so far chosen to stay silent. This interview has been edited for length and clarity. Christopher Rufo: Please begin by setting...

With the passage of time, our body’s repair systems break down; nasty glitches accumulate in our DNA and proteins, metabolism stutters, and cells stop dividing. We are all on a slippery slope to the grave, but research in worms, flies, mice, and monkeys shows that there is nothing inevitable about how fast we slide. Dietary and lifestyle changes – and, perhaps, anti-aging drugs – can slow aging and boost our span of healthy years. A new discovery suggests that a protein in the brain may be a switch for controlling inflammation and, with it, a host of symptoms of aging....

Decline in the hypothalamic Menin may play a key role in aging, according to a study. The findings reveal a previously unknown driver of physiological aging, and suggest that supplementation with a simple amino acid may mitigate some age-related changes. Leng and colleagues showed that Menin, a hypothalamic protein, is a key inhibitor of hypothalamic neuroinflammation. They observed that the level of Menin in the hypothalamus, but not astrocytes or microglia, declines with age. Another change was a decline in levels of the amino acid D-serine, known to be a neurotransmitter and sometimes used as a dietary supplement. The authors...

Depression is a leading cause of disability around the world and contributes greatly to the global burden of disease. Nutrition is essential for the maintenance of normal emotional states. Nutritional therapy is rising up in many disease treatments, but little is known in the depression field. Unbalanced nutrition is implicated in the etiology of depression, potentially hindering treatment. For example, many essential amino acids (EAAs) in serum are changed in patients with depression, such as tryptophan, threonine, leucine, isoleucine, and valine. However, whether EAA contributes to depression and the underlying mechanisms remain largely unknown. Now, researchers, led by Feifan Guo,...

New UC Riverside research shows soybean oil not only leads to obesity and diabetes, but could also affect neurological conditions like autism, Alzheimer’s disease, anxiety, and depression. Specifically, the scientists found pronounced effects of the oil on the hypothalamus, where a number of critical processes take place. “The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and physical growth as well as your response to stress,” “The dogma is that saturated fat is bad and unsaturated fat is good. Soybean oil is a polyunsaturated fat, but the idea that it’s good for you is...

THE brain cells that control ageing have been discovered offering the hope of people living longer Scientists have found that stem cells in the brain's hypothalamus govern how fast ageing occurs in the body. The discovery, made in mice, could lead to new strategies for warding off age-related diseases and extending lifespan, they claim. The hypothalamus was known to regulate important processes including growth, development, reproduction and metabolism. In 2013, researchers made the surprising finding that it also regulates ageing throughout the body. Now, the same scientists have now pinpointed a tiny population of adult neural stem cells, known to...

Inside a Mouse's Brain Lies a Chemical Key to the Fountain of Youth By Greg Thomas Source image via Wikipedia If a scientist came to you with a plan to tweak a gland in the center of your brain so that you may live to be 140 years old, you'd probably back out of the room slowly and go to file a police report, because that's creepy. But new research shows that it's not altogether impossible. A new report from researchers at the Albert Einstein School of Medicine in the Bronx shows that scientists can tinker with the minds of...

The refrigerator is used to lengthen the life of your food, and a new study suggests a similar principle could prolong your life, too. Researchers have found that lowering the body temperature of mice by just 0.5?C extends their lifespan by around 15%. In the future, people might be able to take a drug to achieve a similar effect on body temperature and enjoy a longer life, they say. ... Bruno Conti at Scripps Research Institute in La Jolla, California, US, and colleagues designed genetically engineered mice with a specific brain-cell defect in a region called the lateral hypothalamus. The...

AMSTERDAM — Women who smoke during pregnancy have a higher chance of having a lesbian daughter, neurobiologist and brain researcher Dick Swaab has claimed. Swaab wrote about his theory this week in a University of Amsterdam magazine for graduates, newspaper 'De Telegraaf' reported. In a study on the hypothalamus, Swaab said a person's sexual preference is decided in this region of the brain. It also influences a person's predisposition to aggression, depression and symptoms associated with schizophrenia. The development of an unborn child can be influenced by external substances such as nicotine and amphetamines and the chemicals in diet pills.