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Synthetic Molecules that Adhere Cells Could Galvanize Regenerative Medicine Scientists at the University of California, San Francisco (UCSF) have engineered molecules that act like “cellular glue,” allowing them to direct in precise fashion how cells bond with each other. The discovery represents a major step toward building tissues and organs, a long-sought goal of regenerative medicine. Adhesive molecules are found naturally throughout the body, holding its tens of trillions of cells together in highly organized patterns. They form structures, create neuronal circuits, and guide immune cells to their targets. Adhesion also facilitates communication between cells to keep the body functioning...

UC Irvine biologists have discovered that fats within cells store a class of proteins with potent antibacterial activity, revealing a previously unknown type of immune system response that targets and kills bacterial infections. Steven Gross, UCI professor of developmental & cell biology, and colleagues identified this novel intercellular role of histone proteins in fruit flies, and it could herald a new approach to fighting bacterial growth within cells. The study appears today in eLife, a new peer-reviewed, open-access journal supported by the Howard Hughes Medical Institute, the Max Planck Society and the Wellcome Trust. "We found that these histone proteins...

Pro-Darwin consensus doesn't rule out intelligent design --snip-- (CNN) -- While we officially celebrate the 150th anniversary of the publication of Charles Darwin's "On the Origin of Species" on November 24, celebrations of Darwin's legacy have actually been building in intensity for several years. Darwin is not just an important 19th century scientific thinker. Increasingly, he is a cultural icon. Darwin is the subject of adulation that teeters on the edge of hero worship, expressed in everything from scholarly seminars and lecture series to best-selling new atheist tracts like those by Richard Dawkins and Christopher Hitchens. The atheists claim that...

ScienceDaily: “Slowing Evolution to Stop Drug Resistance” --snip-- For years, evolutionists have pointed to antibiotic resistance as proof of evolution in action. The argument often amounts to this (in simplified form): the fact that certain organisms grow resistant to certain antibiotics is evidence for the evolutionary idea that all animals must have descended from a single ancestor. Collapsing the argument does make it seem a bit silly, but that’s our point. We certainly don’t want to belittle the very real threat of dangerous organisms becoming immune to the best drugs we now have (though the vast majority of microbes are...

Signature in the Cell makes 2009 list of top ten bestselling science books Today Amazon.com announced their bestselling books of 2009 and Signature in the Cell: DNA and the Evidence for Intelligent Design (HarperOne) by Dr. Stephen C. Meyer made the top ten in the science category. According to Amazon.com, books on its 2009 list of best sellers are “[r]anked according to customer orders through October. Only books published for the first time in 2009 are eligible.” The book's publisher, HarperOne, reports that the book is entering its fifth printing in as many months, and continues to sell strongly both...

Molecular biologist Michael Behe described a system made of several interacting parts, whereby the removal of one part would disrupt the functioning of the whole, as irreducibly complex. Both creation scientists and intelligent design proponents highlight examples of irreducible complexity in their studies. The very structure of these systems--with their interdependent parts working all together or not at all--demands design, not chance. Nevertheless, a team of evolutionary molecular biologists think they may have refuted irreducible complexity. They recently studied the parts of a particular cellular machine involved in protein transport, claiming that it was actually reducible to its component parts...

Former Nature editor Philip Ball once commented that ‘there is no assembly plant so delicate, versatile and adaptive as the cell” (1). Emeritus Professor Theodore Brown chose to wax metaphorical by likening the cell to a fully-fledged factory, with its own complex functional relationships and interactions akin to what we observe in our own manufacturing facilities (2). In recent years the seemingly intractable problem of explaining how the first cell came into existence through chance events, otherwise known as the ‘Chance Hypothesis’, has become more acute than ever as scientists have begun to realize that a minimum suite of functional...

Sir Ambrose Fleming: Father of Modern Electronics --snip-- Sir John Ambrose Fleming was a leader in the electronics revolution that changed the world. As a professor at a major university, he carefully researched the evidence for Darwinism, concluding that the theory is not supported by science. He also influenced hundreds of students to evaluate the evidence in science for Darwinism. An outstanding scientist and creationist, he played a significant role in the development and maturation of the early creation movement. As Travers and Muhr wrote, he "had an unusually long and active life," and his life changed the world as...

Experimental Data Force Researchers to Admit There’s “No Such Thing As Junk RNA” Originally, proponents of neo-Darwinian evolution lauded “junk” DNA as functionless genetic garbage that showed life is the result of blind and random mutational events. Then “junk” DNA was disproved by the discovery that the vast majority of DNA is being transcribed into RNA. Did the failure of this Darwinian assumption cause evolutionists to terminate their love affair with biological “junk”? Of course not. They just shifted their argument back, claiming that the cell is full of “junk RNA”—DNA that is being transcribed into RNA but still does...

Shuffling genetic information has long been framed as a biological mechanism that can generate variety as well as fuel evolution. However, new details of a common cellular genetic shuffling process called “crossing over” reveal a tightly controlled system that operates under strict parameters and requires highly specified cellular machinery. It is as if each generation was programmed to have variation, and that variation had strict limitations—limitations that would preclude Darwinian evolution...

Oct 20, 2009 — Every once in awhile it’s fun to look at what biochemists and biophysicists are discovering about the cell. Since you have several trillion of cells in your body, think about some of these cool cell tricks going on inside of you right now...

Weekend Roundup --snip-- Picture Highlight: the new Herschel Space Telescope, is seeing first light and creating dramatic images of gas clouds in the Milky Way...

A buildup of chemical bonds on certain cancer-promoting genes, a process known as hypermethylation, is widely known to render cells cancerous by disrupting biological brakes on runaway growth. Now, Johns Hopkins scientists say the reverse process — demethylation — which wipes off those chemical bonds may also trigger more than half of all cancers. One potential consequence of the new research is that demethylating drugs now used to treat some cancers may actually cause new cancers as a side effect. "It's much too early to say for certain, but some patients could be at risk for additional primary tumors, and...

One of the current handicaps of cancer treatments is the difficulty of aiming these treatments at destroying malignant cells without killing healthy cells in the process. But a new study by McMaster University researchers has provided insight into how scientists might develop therapies and drugs that more carefully target cancer, while sparing normal healthy cells Mick Bhatia, scientific director of the McMaster Stem Cell and Cancer Research Institute in the Michael G. DeGroote School of Medicine, and his team of investigators have demonstrated – for the first time – the difference between normal stem cells and cancer stem cells in...