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In April 2005, a virulent strain of influenza hit a maximum-security forensic psychiatric hospital for men that’s midway between San Francisco and Los Angeles. John J. Cannell, a psychiatrist there, observed with increasing curiosity as one infected ward after another was quarantined to limit the outbreak. Although 10 percent of the facility’s 1,200 patients ultimately developed the flu’s fever and debilitating muscle aches, none did in the ward that he supervised. WINTER WOES. Cold-weather wear and the sun’s angle in the winter sky limit how much ultraviolet light reaches the skin. This can add up to a deficiency in production...

Study enrolling hospitalized adults with COVID-19 in Nebraska A randomized, controlled clinical trial to evaluate the safety and efficacy of the investigational antiviral remdesivir in hospitalized adults diagnosed with coronavirus disease 2019 (COVID-19) has begun at the University of Nebraska Medical Center (UNMC) in Omaha. The trial regulatory sponsor is the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. This is the first clinical trial in the United States to evaluate an experimental treatment for COVID-19, the respiratory disease first detected in December 2019 in Wuhan, Hubei Province, China. The first trial participant...

Russia is beginning the production of an antiviral drug it has approved for the treatment of Ebola, a news report said, while a senior World Health Organization official urged stronger international efforts to contain the virus outbreak in West Africa. The Russian Health Ministry has approved the production of the drug, Triazavirin, developed by researchers at the Institute of Organic Synthesis in the Urals region, said Sergei Kortov, a senior official at a regional patent service, the Novy Region news agency reported Tuesday. The approval followed 20 years of research and a series of clinical trials on 100 volunteers from...

Research published in the journal Genetics suggests that mutagenic drugs designed to kill viruses may make them strongerAs the flu season continues in full-swing, most people can appreciate the need for drugs that stop viruses after they take hold in the body. Despite this serious need for new drugs, a team of researchers from the University of Texas at Austin raise serious concerns about an emerging strategy for stopping viral infections. According to their research report appearing in the January 2010 issue of the journal GENETICS, medications that cause viruses to die off by forcing their nucleic acid to mutate...

CHICAGO (Reuters) – U.S. researchers have discovered antiviral proteins in cells that naturally fight off influenza infections, a finding that may lead to better ways to make vaccines and protect people against the flu. They said a family of genes act as cell sentries that guard cells from an invading influenza virus, the team reported on Thursday in the journal Cell. "This prevents the virus from even getting into the cell," said Stephen Elledge of Harvard Medical School and a Howard Hughes Investigator at Brigham & Women's Hospital. "It is out there fighting the flu all of the time," Elledge...

An unlicensed intravenous form of the antiviral drug Relenza saved the life of a woman with a severe illness resulting from infection by the pandemic H1N1 influenza virus, British doctors reported today in the journal Lancet. Dr. Michael Kidd and Dr. Mervyn Singer of the University College London Hospitals were treating the virus, commonly known as swine flu, in a 22-year-old woman who had contracted it after undergoing chemotherapy for Hodgkin's disease. The woman had increasing shortness of breath, build-up of fluid in both lungs and was progressively deteriorating. Physicians had given her Tamiflu and Relenza, which is normally given...

Almost 90 per cent of the world's population will not have timely access to affordable supplies of vaccines and antiviral agents in the current influenza pandemic, but it is possible that inexpensive generic drugs that are readily available, even in developing countries, could save millions of lives. > "At a scientific meeting in 2008 we heard that all of the people who developed bird flu in Indonesia, and did not receive antiviral treatment, died. This observation is terrifying. If this particular virus were to develop efficient human-to-human transmission we could see a global population collapse. >

Tamiflu comes from an herb To live in a world that's saturated with natural anti-viral medicine and then not even acknowledge it in the media is beyond bizarre. It's Twilight Zone-like. It's like we've been teleported to an alternate universe where anti-viral plants have disappeared... or at least everyone is pretending they have. Where do you think Tamiflu comes from, by the way? It's extracted from the Traditional Chinese Medicine herb called Star Anise. It's one of hundreds of different anti-viral herbs found in Chinese Medicine, not to even mention anti-viral herbs from South America, North America, Australia, Africa and...

Antiviral coating may help fight epidemics 15:00 14 April 2006 From New Scientist Print Edition BANKNOTES, vending machines and photocopiers could help fight off future epidemics if a novel antiviral coating can be made to work safely. Materials researcher Guagang Ren at Queen Mary, University of London, has discovered a raft of metal, metal oxide and ceramic nanoparticles that have strong antiviral properties. He hopes to create a face mask impregnated with the particles to destroy certain airborne viruses before people breathe them in. Ren has joined forces with UK-based Qinetiq Nanomaterials and London research firm Retroscreen Virology. Qinetiq's technology...

Marketplace investigates illegal sales of a coveted antiviral drug. Tamiflu has been touted as a miracle, should influenza pandemic strike. Trouble is, it’s growing hard to get hold of through legal channels. We take a journey to show who’s been cashing in on our flu fears. CBC MARKETPLACE: HEALTH » BUYING DRUGS ONLINE Flu's gold: Buying into pandemic fear Broadcast: January 29, 2006 The golden pill at the heart of the scheme is an antiviral called Tamiflu. This is a story about a hunt for a prescription drug that everybody wants, but nobody can get. It’s a hunt that leads...

WEDNESDAY, Feb. 2 (HealthDayNews) -- Researchers report that they've been able to stop a smallpox-like virus in mice in just eight days, a development that could lead to more effective treatments for other kinds of illnesses in humans. While the treatment is not ready for use in people, "it represents a new approach toward antiviral therapies," said Dr. Ellis Reinherz, a researcher at the Dana-Farber Cancer Institute and co-author of the study in the February issue of the Journal of Clinical Investigation. Doctors banished the deadly smallpox virus from the earth in the 1970s, and universal vaccination against the disease...

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03/29/04 -- Viruses, often able to outsmart many of the drugs designed to defeat them, may have met their match, according to new research from the University of Wisconsin-Madison. The findings show that the introduction of a harmless molecule that uses the same machinery a virus needs to grow may be a potent way to shut down the virus before it infects other cells or becomes resistant to drugs. The results are published in the March issue of the journal, Antimicrobial Agents and Chemotherapy. "When a virus encounters a susceptible cell, it enters and says, 'I'm now the boss,'" explains...