ROSIE O’DONNELL wrecked her marriage when she “went nuts” in a Thanksgiving Day tantrum fueled by booze and drugs! In a blockbuster world exclusive, The National ENQUIRER can reveal the untold story of Rosie’s relationship-ending meltdown, which left terrified wife Michelle Rounds locked in a bathroom and fearing for the safety of both herself and their 2-year-old daughter. Multiple sources have confirmed the shocking incident took place last November at Rosie’s home on Casey Key – north of Sarasota, Fla. – with raging Rosie throwing a holiday tantrum in front of Michelle’s visiting relatives!