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Weight-controlling gene is discovered
UPI ^ | 09/06/07

Posted on 09/06/2007 8:49:14 AM PDT by nypokerface

DALLAS, Sept. 6 (UPI) -- U.S. scientists have determined a single "skinny gene" might alone control whether a body tends to accumulate fat.

"From worms to mammals, this gene controls fat formation," said Dr. Jonathan Graff of the University of Texas Southwestern Medical Center, the study's senior author. "It could explain why so many people struggle to lose weight and suggests an entirely new direction for developing medical treatments that address the current epidemic of diabetes and obesity."

The gene, called adipose, was discovered more than 50 years ago but its mechanism was not determined.

In the new study, researchers discovered the gene is likely a high-level "master switch" that is dose-sensitive, meaning the various combinations of its variants lead to a range of body types from slim to medium to obese.

"This is good news for potential obesity treatments, because it’s like a volume control instead of a light switch; it can be turned up or down, not just on or off," Graff said. "Eventually, of course, the idea is to develop drugs to target this system, but that’s in the years to come."

The research appears in the journal Cell Metabolism.


TOPICS: Culture/Society
KEYWORDS: health; healthcare; obesity; weight
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1 posted on 09/06/2007 8:49:14 AM PDT by nypokerface
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To: nypokerface
In the new study, researchers discovered the gene is likely a high-level "master switch"

My master switch is beer.
2 posted on 09/06/2007 8:51:27 AM PDT by Man50D (Fair Tax, you earn it, you keep it!)
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To: nypokerface

Scientists discovered this gene is responsible for control the movement of the arms to the mouth region. In overweight people, the gene refuses to stop working, and they keep shoveling food into their mouths.


3 posted on 09/06/2007 8:52:43 AM PDT by flashbunny (<--- Free Anti-Rino graphics! See Rudy the Rino get exposed as a liberal with his own words!)
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To: flashbunny

Wow, only the second post before the fat-bashing began.


4 posted on 09/06/2007 8:56:48 AM PDT by mvpel (Michael Pelletier)
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To: nypokerface
The gene, called adipose, was discovered more than 50 years ago but its mechanism was not determined.

Misleading headline.

5 posted on 09/06/2007 8:59:42 AM PDT by ClearCase_guy (The broken wall, the burning roof and tower. And Agamemnon dead.)
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To: nypokerface

What is this about the 10th new study with the 10th new reason why it is impossible not to be fat


6 posted on 09/06/2007 9:00:23 AM PDT by uncbob (m first)
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To: mvpel

Now that smokers have been beaten into oblivion, the obese will take their place as the whipping boys of society.


7 posted on 09/06/2007 9:00:56 AM PDT by mysterio
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To: Man50D

you too huh... I knew I was not alone.. lol


8 posted on 09/06/2007 9:01:22 AM PDT by MD_Willington_1976
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To: nypokerface
The absolute weight control gene is right on the front of your face. It is call: the mouth. Keep the damned thing shut and don’t push 8,000 calories a day down your pie hole, and you won’t weight 455 pounds on your 5-7 frame.
9 posted on 09/06/2007 9:02:14 AM PDT by RetiredArmy (The American Republic is slowing dying, and no one cares.)
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To: nypokerface

I thought the “master switch” was called “self-control”?


10 posted on 09/06/2007 9:03:17 AM PDT by Titus Quinctius Cincinnatus (Want authentic 1st century Christianity? Visit a local, New Testament Independent Baptist church!)
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To: flashbunny

And the gene tied to some people resembling a giant anal orifice remains undiscovered.


11 posted on 09/06/2007 9:03:25 AM PDT by Master Shake
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To: nypokerface
I like to look in the shopping carts of others at the grocery store. I notice the more bread based products in the cart the fatter the shopper and the more fresh produce in the cart the thiner the shopper.
12 posted on 09/06/2007 9:03:32 AM PDT by elizabetty (Ron Paul - Because Moonbats Need Choices Too!)
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To: mysterio
Photo Sharing and Video Hosting at Photobucket

Here. Here's the sacrificial ham. Go after him first!

When liberals go after their own, that's when it gets interesting.

13 posted on 09/06/2007 9:04:54 AM PDT by dragonblustar (Freedom of Speech is for everyone, not just liberals.)
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To: Master Shake

awwwww.


14 posted on 09/06/2007 9:05:59 AM PDT by flashbunny (<--- Free Anti-Rino graphics! See Rudy the Rino get exposed as a liberal with his own words!)
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To: mvpel

Play the victim card. It burns calories.


15 posted on 09/06/2007 9:06:20 AM PDT by flashbunny (<--- Free Anti-Rino graphics! See Rudy the Rino get exposed as a liberal with his own words!)
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To: flashbunny

Gee, it must be nice to have such a holier than thou attitude.

Get off your high horse. There are people who are by clinical definition obese that eat no more and some times less than your average person and certainly well within the calorie guidelines of the medical profession.

Scientists are now discovering the facts behind what many people have been telling them for years. Genes, viruses, insulin response are all recognized medical conditions that we are just now beginning to understand how they impact the human metabolism. Even the types of food can impact the metabolism and people’s body respond differently. My wife gains weight if she eats too much meat and has to follow the food pyramid very closely. I gain weight rapidly if I follow the food pyramid because it contains too many carbohydrates. My doctor tells me that my body produces too much insulin in response to carbohydrates.

Do some people over eat and/or under exercise ... sure. But do not paint with such a wide brush as to believe that everyone is the same and can be simply treated the same way.


16 posted on 09/06/2007 9:06:28 AM PDT by taxcontrol
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To: Titus Quinctius Cincinnatus

You’re “fat bashing”!!!


17 posted on 09/06/2007 9:06:50 AM PDT by flashbunny (<--- Free Anti-Rino graphics! See Rudy the Rino get exposed as a liberal with his own words!)
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To: Master Shake
And the gene tied to some people resembling a giant anal orifice remains undiscovered.

Photo Sharing and Video Hosting at Photobucket

No hope for Rosie.

18 posted on 09/06/2007 9:07:54 AM PDT by dragonblustar (Freedom of Speech is for everyone, not just liberals.)
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To: nypokerface
"'This is good news for potential obesity treatments, because it’s like a volume control instead of a light switch; it can be turned up or down, not just on or off,' Graff said. 'Eventually, of course, the idea is to develop drugs to target this system, but that’s in the years to come.'"

It's always the same with this stuff.
The solution's always, "years to come".

Translated it means anyone amped-up over hearing the *good news* will be dead & gone.

...by then.

19 posted on 09/06/2007 9:10:22 AM PDT by Landru (That does it, no sleep number for you pal.)
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To: nypokerface
Photo Sharing and Video Hosting at PhotobucketPhoto Sharing and Video Hosting at Photobucket

I don't know. Between the two of them, fat can look cool, especially when you don't give a damn.

20 posted on 09/06/2007 9:10:47 AM PDT by dragonblustar (Freedom of Speech is for everyone, not just liberals.)
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