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Cancer protection secret revealed ( how cells switch a gene called p53,)
BBC ^
| 00:01 GMT, Sunday, 1 February 2009
| BBC Staff
Posted on 01/31/2009 8:05:05 PM PST by Ernest_at_the_Beach
Scientists say they have discovered a missing link in the way cells protect themselves against cancer.
Zebrafish share the p53 gene with humans
They have uncovered how cells switch a gene called p53, which can block the development of tumours, on and off.
The researchers say the finding has important implications for cancer treatment and diagnosis.
The study, published in Genes And Development, was carried out by teams of scientists in Singapore and the University of Dundee.
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Discovering how it is regulated will have incredibly important implications in the development of better drugs and ways to diagnose cancer
Lesley Walker Cancer Research UK
|
The p53 gene, first discovered 30 years ago, plays a vital role in keeping the body healthy by ordering damaged cells to commit suicide, or by stopping them dividing while key repair work is carried out.
In half of all cancers the gene is either damaged or inactive, giving damaged cells a free rein to keep dividing and form cancer.
In the latest study, the scientists used a genetic trick to make zebrafish turn green when the p53 gene was switched on to explore the way it was regulated.
(Excerpt) Read more at news.bbc.co.uk ...
TOPICS: Culture/Society; Extended News; News/Current Events
KEYWORDS: cancer; cancerresearch; health; medicine; p53
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To: neverdem; NormsRevenge
To: justiceseeker93
To: Ernest_at_the_Beach
Another piece of the puzzle.
4
posted on
01/31/2009 8:20:24 PM PST
by
TChad
To: Ernest_at_the_Beach; SouthTexas; glock rocks; Grampa Dave; SierraWasp; fish hawk; Brad's Gramma
5
posted on
01/31/2009 8:21:55 PM PST
by
tubebender
(Your Tag Line offends me...)
To: Ernest_at_the_Beach
6
posted on
01/31/2009 8:26:17 PM PST
by
Earthdweller
(Socialism makes you feel better about oppressing people.....)
To: Ernest_at_the_Beach
pretty cool thanks for posting
7
posted on
01/31/2009 8:27:00 PM PST
by
Flavius
To: Ernest_at_the_Beach
Nifty stuff! God does awesome work.
8
posted on
01/31/2009 8:36:03 PM PST
by
OneWingedShark
(Q: Why am I here? A: To do Justly, to love mercy, and to walk humbly with my God.)
To: Ernest_at_the_Beach
So, now we eat Zebra fish twice a day, right?
.
9
posted on
01/31/2009 8:49:48 PM PST
by
Seaplaner
(Never give in. Never give in. Never...except to convictions of honour and good sense. W. Churchill)
To: TigersEye; yorkie
10
posted on
01/31/2009 8:53:12 PM PST
by
pandoraou812
(Don't play leapfrog with a unicorn! ...........^............)
To: Seaplaner
To: Ernest_at_the_Beach
12
posted on
01/31/2009 8:59:55 PM PST
by
grey_whiskers
(The opinions are solely those of the author and are subject to change without notice.)
To: tubebender
So we are supposed to eat those little things?
13
posted on
01/31/2009 9:17:10 PM PST
by
SouthTexas
(Danger, Danger .. Will Robinson)
To: Ernest_at_the_Beach
" Discovering how it is regulated will have incredibly important implications in the development of better drugs and ways to diagnose cancer." Lesley Walker
Cancer Research UK
It seems to me this discovery about how this gene is controlled in cells is perhaps, in the long run, more important in finding ways to prevent cells from turning cancerous in the first place.
14
posted on
01/31/2009 9:26:38 PM PST
by
Balata
To: Ernest_at_the_Beach
15
posted on
01/31/2009 9:44:25 PM PST
by
neverdem
(Xin loi minh oi)
To: Ernest_at_the_Beach
the scientists used a genetic trick to make zebrafish turn green when the p53 gene was switched on
—
Very interesting. Thanks!
16
posted on
01/31/2009 10:23:55 PM PST
by
NormsRevenge
(Semper Fi ... Godspeed.)
To: Ernest_at_the_Beach; All
Resveratrol, Selenium, Zinc, Vitamins A C E and D (from sunlight) - All have anti-cancer and cancer fighting properties.
Research shows that Resveratrol, and Selenium both turn TP53 on, IIRC.
17
posted on
01/31/2009 10:32:14 PM PST
by
PeaceBeWithYou
(De Oppresso Liber! (50 million and counting in Afganistan and Iraq))
To: PeaceBeWithYou
It looks like dark chocolate and red wine are the answers to some of lifes greatest mysteries.
18
posted on
01/31/2009 11:01:48 PM PST
by
Balata
To: SouthTexas
Come on, be series. They have been putting them on Pizzas for years...
19
posted on
02/01/2009 7:46:57 AM PST
by
tubebender
(Your Tag Line offends me...)
To: PeaceBeWithYou
and Selenium both turn TP53 on, IIRC. There was a minor study done locally 30 years ago on the high incidence of cancer in women and one of the things they found was the lack of Selenium in our soils.
20
posted on
02/01/2009 7:54:36 AM PST
by
tubebender
(Your Tag Line offends me...)
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