Posted on 01/21/2026 6:52:41 AM PST by daniel1212
Many people who successfully lost weight on Ozempic and other GLP-1 agonist drugs are having trouble weaning themselves off the injectables, according to the BBC, because the hunger for food comes roaring back with a vengeance — and hence the pounds start creeping up again, hinting that patients are likely to develop life-long dependencies on the substances.
“For the first 38 years of my life, I was overweight — now I’m six stone (38kg) [83 pounds] lighter,” Tanya Hall, a Wegovy user who can’t get off the drug, told the news organization. “Therefore, there’s part of me that feels like there’s an addiction to keep it going because it makes me feel the way that I feel, it makes me feel in control.”
This is borne out by research that found patients who stop using these medications often gain much of their weight back....
For patients who do get off the drugs, they tend to gain two thirds of their lost weight back, according to research by Ozempic maker Novo Nordisk. Physician Hussain Al-Zubaidi told the BBC that he’s seen patients gain 60 to 80 percent back of the weight they lost.
(Excerpt) Read more at futurism.com ...
Dear FRiends,
We need your continuing support to keep FR funded. Your donations are our sole source of funding. No sugar daddies, no advertisers, no paid memberships, no commercial sales, no gimmicks, no tax subsidies. No spam, no pop-ups, no ad trackers.
If you enjoy using FR and agree it's a worthwhile endeavor, please consider making a contribution today:
Click here: to donate by Credit Card
Or here: to donate by PayPal
Or by mail to: Free Republic, LLC - PO Box 9771 - Fresno, CA 93794
Thank you very much and God bless you,
Jim
No shocker here. Eat less or more sensibly and work out/walk ya lazy shiite.
“For patients who do get off the drugs, they tend to gain two thirds of their lost weight back”
So 1/3 of the weight loss is lasting. That’s not terrible.
I’ve seen this in a loved one. He was put on Trulicity for type-2 diabetes to control blood sugar (the original purpose of these GLP drugs) and his appetite decreased markedly. When his insurance year renewed and he was hit with a $650 monthly prescription cost, he went off of them. His food intake doubled.
So what? People take a lot of drugs their whole life. I take allopurinol daily and will the rest of my life.
Need to have a waiting period for forks and start taxing food at an exorbitant amount!
Problem solved!
Semi glutetides should be OTC.
So it’s just like every other weight loss method. Whatever you do you gotta stick to it.
I have had an interesting experience with these drugs.
I’ve never been a candidate for the Biggest Loser TV show, but I’ve been +30# - +50# most of my life. Low carb/no carb works for me but I can’t stick to it.
I started tirzepatide 17 months ago at the lowest dose (Below the “effective dose”). Immediately, and for the first time, I stopped thinking about food. Not “stopped being hungry”.
It took a bit of time to realize something was different. I certainly wouldn’t have said, about myself, before this experience, that I thought about food like an addict thinks about meth or crack - but that’s about the truth.
Driving to work - “where will I get lunch today?”. Driving home - “Should I stop at the store or do we have food at home for dinner?”
2.5 mg of tirzepatide, that stopped imemdiately and never came back.
There is definitely something about the brain-gut connection that these drugs disrupt, that’s independent of the metabolic effects of the higher doses.
Interesting stuff.
Except for the part where you're injecting a drug into your body, as a substitute for self-control and self-discipline (as in, the discipline to go for a walk, or do some other form of exercise).
This really depends on the patient. There are a lot of people who go on Ozempic and other GLP drugs and lose absolutely no weight and can go on and off them with zero side effects. There is a lot of sensationalism around Ozempic.
When I saw “Weight Train” in the headline I thought this was about people getting off Ozempic and onto kettlebells.
Surprise, surprise!
Exactly. And if your old and fat like me, it adds years and energy to what would otherwise be a miserable existence crippled by weight.
I lost 200lbs woth Keto and fasting but the last 50 are eluding me. After a two year plateau, I decided I needed help. I don’t care if I spend the last 25 years taking a weekly injection.
It’s a helluva lot better than the multiple inhections daily of T2D like my older brother who refuses to give up the bread and potatoes.
“It’s going to be a lifetime thing”
Ya think? Doh! Humans require not a lot of food actually, particularly or especially sedentary people. That’s why there are so many fatties now. Massive amounts of calories heavily skewed towards carbohydrate.
Statistically, I read that 90% of the people who lose their excessive fat stores gain it all back (and more) within 2 years.
Ya think? Doh! Humans require not a lot of food actually, particularly or especially sedentary people. That’s why there are so many fatties now. Massive amounts of calories heavily skewed towards carbohydrate.
Intermittent and long-term fasting has been shown to slow down the aging process.
I took ozempic, I lost 75 pounds and at the same time I changed my eating habits. I’ve kept it off and no longer take ozempic. Changing your habits is key. If you don’t do that nothing will change.
CC
The most effective method is the Venezuelan diet. Just vote socialists into power - no drugs needed.
It’s like government programs:
If you think the problems they cause are bad, wait till you see their solutions.
I’m old enough to observe that obesity ballooned along with the government’s telling people what to eat and what not to eat, increasingly dictating how they must live, and subsidizing garbage-filled grocery carts.
It’s as if Big Government, Big Food, and Big Pharma are one Big morbidly obese family.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.