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Posted on 01/08/2026 1:51:21 PM PST by nickcarraway
People who stop taking weight-loss injections such as Wegovy and Mounjaro regain pounds much faster than those who halt exercising and dieting, a new medical study shows.
Research published in The British Medical Journal this month suggests that people lose around a fifth of their body weight when taking the jabs. But once they quit them, they regain 0.8 kg per month on average, meaning they return to their pre-treatment weight in around a year-and-a-half, according to the findings.
The study was based on the analysis of more than 9,000 adults worldwide taking weight management medications (WMMs).
Novo Nordisk, the parent company of Wegovy, told Newsweek that this study "highlights the chronic nature of obesity and suggest that ongoing treatment is necessary."
Eli Lilly and Company, the parent company of Mounjaro, told Newsweek: "When treatment is stopped, weight can return, which reflects the biology of the condition rather than a lack of effort."
Newsweek reached out to the Centers for Disease Control and Prevention (CDC) via email for comment.
The findings come as usage of weight-loss jabs surges in the United States — a Rand Corporation survey from last August found that nearly 12 percent of Americans had used glucagon-like peptide (GLP-1) drugs, including Wegovy and Mounjaro, for weight loss.
The findings also suggest that users need to take the drugs long-term for continued effect, which could have a large financial impact on them.
What To Know
The study, published in The BMJ on January 7, summarized evidence from 37 trials involving 9,341 participants, most of whom received newer "incretin mimetic" drugs such as semaglutide (Wegovy) or tirzepatide (Mounjaro).
The key findings included:
After stopping WMMs, adults regained an average of 0.4 kg (0.9 lb) per month; for newer drugs,
(Excerpt) Read more at newsweek.com ...
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Not to mention an unknown health effect from long term usage.
I have been on Mounjaro for a while. My doctor has been kind of a nagging mom making sure that I was changing my eating habits to adjust my head and my body . From the first day I understood that I had to develop and excercise plan and an healthier eating plan.
The drug has been a life saver. But I have to do my part as well.
Lots of people don’t take the time to understand how it works and they just keep eating crap and sitting around.
These drugs have been around for a long, long time. The long term impacts are well studied.
I know somebody who’s been going on and off Mounjaro, and claims the weight she gained back was because of her hormones. It could be a factor, but she’s also a diabetic who doesn’t take her diet seriously because she’s (sporadically) taking one of these “miracle” weight loss drugs.
That's amazing. Usually doctors only do that in movies or TV.
Make GLP-1’s OTC so all the fat folks here in the south can get skinny. The health benefits of GLP-1’s far outweigh the downside.
How do you know that?
Are you saying Southerners are fatter than others?
Diet and exercise still works.
Just say “No” to drugs...
Come down here and park in any Walmart parking lot and you’ll see probably 90% are over weight. Watching them waddle into the stores huffing and puffing is horrid.
Not everything is political.
Fried food and sweet tea in Southern cuisine.
Diet and exercise still sucks. I have.to get off the couch. No way am I going through that charade again.
Why waddle into the store when you can ride in style with an electric cart.
Butt extending well past the seat on both sides.
Probably the same for the pill.
It’s a lifetime use drug.
Just what big pharma ordered.
Go out to eat in Chicago sometime. They’re fat as hell—they all look like they’ve been inflated with airhoses, à la Dig Dug…
i asked grok if it was true that you had to take GLP-1 drugs the rest of your life or otherwise you would gain the lost weight back?
grok started off with: “That’s absolutely not true!”
but later on in the exposition, Grok noted that the weight would be gained back if/when one stopped taking the drugs!
Yep, those scooters stay busy.
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