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Posted on 12/16/2025 10:13:29 AM PST by SeekAndFind
A new review of more than 120 studies concluded that there is little evidence supporting the use of medical cannabis for a variety of conditions, including insomnia.
The U.S. Food and Drug Administration has approved cannabinoids, a chemical compound extracted from cannabis, for chemotherapy-induced nausea and vomiting and seizures, among other conditions. Many patients use cannabinoids or other medical cannabis for other conditions, such as anorexia, insomnia, and chronic pain, either through off-label prescriptions or through state availability.
A look at research published from January 2010 through September, though, showed that for many conditions, “evidence is insufficient,” researchers with the University of California, Los Angeles (UCLA) and other institutions said in the review, which was published Nov. 26 by the Journal of the American Medical Association.
The evidence base featured more than 120 studies, including some randomized. placebo-controlled clinical trials.
“While many people turn to cannabis seeking relief, our review highlights significant gaps between public perception and scientific evidence regarding its effectiveness for most medical conditions,” Dr. Michael Hsu, one of the authors and a health sciences clinical instructor at the UCLA Health Department of Psychiatry and Biobehavioral Sciences, said in a statement. “Clear guidance from clinicians is essential to support safe, evidence-based decision-making when discussing medical cannabis with their patients.”
He also said, “Patients deserve honest conversations about what the science does and doesn’t tell us about medical cannabis.”
At the same time, the products can lead to problems such as dry mouth, diarrhea, and dizziness, and long-term health outcomes are still being studied.
There is evidence supporting treating certain conditions, such as nausea and vomiting, with medical cannabis or cannabinoids, the researchers said. Limitations of the research included not covering the risk of bias for the studies that were analyzed, and some of the studies analyzed for the review being observational.
“Further research is crucial to better understand the potential benefits and risks of medical cannabis,” Hsu stated. “By supporting more rigorous studies, we can provide clearer guidance and improve clinical care for patients.”
Conflict of interest disclosures included Hsu reporting being on the advisory board for Healthy Gamer, a platform that creates content and provides mental health coaching for youth. The research was supported by the Greater Los Angeles Veterans Affairs Medical Center. The center did not have a role in the design or conduct of the study, or the interpretation of the data, the authors said.
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Marijuana causes psychosis and does more harm than good.
I’ve personally watched it stop seizures first hand many times. I’ve always watched it stop a seizure before it even started. Until you see something like that first hand, you’re ignorant as to the medical effects and uses it has.
This has been known for decades, but the cannabis users have always dismissed this by using anecdotal examples of grandma and her glaucoma. We all remember when they claimed cannabis was just going to be used for medicinal purposes. We all knew it was a lie as it remains a lie. Psychosis, paranoia, and bi-polar have been among the consequences. Cannabis has been a blight on society.
25+ years of regular use and I'm doing fine. I even still vote Republican! I think those that experience psychosis from weed already experienced it or will at one point. Too many long term users alive and well today for it to be the absolute root cause of psychosis. Weak people will always be week people, with or without the weed.
You cannot use the fact that there was no seizure, because someone got high. You cannot prove that a seizure is imminent. I am sure Doctors could with fancy equipment. MJ is a drug, it has benefits that stoners like, it does not have benefits medically.
Duh.....Government’s solution to smoking...patches, gum, vaping, doping...
And there have always been a myriad of other and better treatment options available.
I know someone who uses gummies for both anorexia and anxiety. Sometimes it helps, sometimes it doesn’t. As far as the anxiety relief, it obviously is short term, and is just a bandaid, but because of government interference, his doctors aren’t allowed to prescribe actual anti-anxiety meds, as he is also a chronic pain patient. Of course, those meds are also just bandaids, and highly addictive, as well, so the gummies are a better alternative.
Cannabis has improved my sleep and back pain immensely. The only problem is that it doesn’t help with my weight loss goals.
so much effort to ban tobacco smoking then pot smoking is legalized?
It makes no sense to me.
Wow man, like you no, I thot, it wasn’t bad for mi.
Yep, over 50 years here. It’s been great life, self-employed, retired at 60. Complained to doctor about getting forgetful at 76, got brain MRI, came back normal.
5 out of 5 big pharmas approve of this article. I went through months of chemo and MMJ controlled nausea, cramps insomnia, and gave me an appetite. It also spared me from having to take a bunch of meds to control the effects of chemo that had their own side effects.
Studies that are a “review” of “selected” earlier studies are too easy to skew, to get the result you want.
my medical care is of no concern to you
It will help nausea and get rid of a headache. That’s about it.
The dopers all say the same thing:
1 - “it’s controlled, so no good studies have been done” and/or
2 - PHARMA doesn’t want the studies released ‘cause marijuana CURES everything they sell us their poison to control but not cure, dErP!
Without blinking at the mental gymnastics they go through to make those statements.
I personally - in my humble medical opinion - don’t believe MJ to have any repeatable, quantifiable, medical utility.
But, to each his own. Just don’t toke and drive
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