Posted on 07/23/2025 9:06:11 PM PDT by ConservativeMind
A new study has found that a commonly prescribed anti-nausea medication is associated with a better prognosis for women with early-stage breast cancer, particularly triple-negative breast cancer.
The research team evaluated Cancer Registry of Norway data of 13,811 women diagnosed with early-stage breast cancer between 2008 and 2020 who received both chemotherapy and anti-nausea medications that are used to prevent chemotherapy-induced nausea and vomiting.
In women with breast cancer, the use of the anti-nausea medication aprepitant during chemotherapy treatment was linked to an overall 11% lower risk of developing cancer recurrence and 17% lower risk of breast cancer-related death in the 10-year follow-up period. When the researchers looked at anti-nausea medications of other drug classes, they found no association of their use with cancer outcomes.
Notably, when the researchers looked at breast cancer subtypes, they found the association between aprepitant and better survival outcomes was even stronger in women with triple-negative breast cancer, with the study showing a potential 34% reduced risk of cancer recurrence and 39% reduced risk of death among this cohort.
Chemotherapy-induced nausea and vomiting is a prevalent side-effect of systemic chemotherapy in early-stage breast cancer patients, affecting up to 60% of patients. Recent guidelines recommended the use of aprepitant only in patients treated with chemotherapy highly likely to induce vomiting and nausea.
Dr. Chang said the findings of this study suggest that expanding the use of aprepitant as a routine antiemetic regimen during chemotherapy treatment warrants further exploration.
"Generally speaking, when aprepitant is taken, it's during the first three days of chemotherapy treatment. Given the association between aprepitant and improved cancer outcomes uncovered in this study, it has led us to wonder if even greater survival would be observed if longer-term use of aprepitant was factored into the patients' dosing schedule," Dr. Chang said
(Excerpt) Read more at medicalxpress.com ...
To think an anti-nausea drug can do anything to kill off triple-negative breast cancer, is amazing. It provided an 11% decrease in cancer recurrence and a 17% lower likelihood of a cancer-related death, over 10 years.
Interesting. 30 years ago, I stopped my boyfriend’s brain tumor(oligodendroglioma) with the anti nausea drug thalidomide, which was taken off the market. Took weeks of preparation internet research to find them.
I had to get it through a group of gay guys in San Francisco who were able to get the government let them have it.
The mechanism for was to stop the blood supply that feeds the tumor. The deformaties of babies were because limbs didn’t get a blood supply.
Lol... he got well, stole all my money and silver!
Well, you know... that road to hell and good intentions....
he’s still alive and I haven’t thought about the rat for 30 years. That’s nice. 👍
“To think an anti-nausea drug can do anything to kill off triple-negative breast cancer, is amazing. It provided an 11% decrease in cancer recurrence and a 17% lower likelihood of a cancer-related death, over 10 years.”
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Perhaps with less nausea, they were able to ingest more nutrition.
This should have a beneficial effect on the body’s overall survival rate.
Interesting story about the thalidomide.
Interesting story about the a$$hole who stole your money and possessions. I experienced the same thing 35 years ago. (his initials aren’t JR, are they — LOL!)
Bkmk
LMBO!! Thanks, I needed that.
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