Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Researchers Develop Breakthrough Covid-19 Vaccine
Israel21c ^ | November 24 | Nicky Blackburn

Posted on 11/25/2024 1:13:45 PM PST by nickcarraway

Needle-free nano-vaccine, cheap to produce, requires no refrigeration and is administered as nasal spray, making it accessible to developing nations.y

A pair of scientists from Israel and Portugal have developed an inexpensive and effective new nano-vaccine against Covid-19, which can be stored at room temperature and administered as a nasal spray.

The breakthrough vaccine trains the immune system against all common Covid-19 variants with the same efficiency as existing vaccines.

But it does not require an injection or a cold supply chain and cold storage, making it ideal for vaccinating at-risk populations in developing countries and in remote regions.

In addition, the scientists believe it paves the way to the development of simpler, more effective, and less expensive vaccines in the future.

Prof. Ronit Satchi-Fainaro from Tel Aviv University’s Faculty of Medical and Health Sciences developed the vaccine in collaboration with Prof. Helena Florindo at the University of Lisbon.

“The new nano-vaccine’s development was inspired by a decade of research on cancer vaccines,” said Satchi-Fainaro. “When the Covid-19 pandemic began, we set a new goal: training our cancer platform to identify and target the coronavirus.”

Satchi-Fainaro said the researchers did not rely on full protein expression via mRNA, unlike the Moderna and Pfizer Covid vaccines.

“Instead, using our computational bioinformatics tools, we identified two short and simple amino acid sequences in the virus’s protein, then synthesized them, and encapsulated them in nanoparticles.”

“Our nano-vaccine offers a significant advantage over existing vaccines because it is needle-free and administered as a nasal spray,” said Satchi-Fainaro.

“This eliminates the need for skilled personnel such as nurses and technicians to administer injections, while also reducing risks of contamination and sharps [biohazardous] waste. Anyone can use a nasal spray, with no prior training.”

Stored as powder, as effective as Pfizer

Another major advantage of the nano-vaccine is its minimal storage requirements.

Moderna’s sensitive mRNA-based vaccine must be kept at -20°C and Pfizer’s at -70°C, generating great logistic and technological challenges, such as shipping in special aircraft and ultra-cold storage from the factory to the vaccination station.

The synthetic nanoparticles are far more durable and can be stored as a powder at room temperature.

“There’s no need for freezing or special handling,” said Satchi-Fainaro. “You just mix the powder with saline to create the spray. For testing purposes [as part of the EU’s ISIDORe Integrated Services for Infectious Disease Outbreak Research feasibility program] we shipped the powder at room temperature to the INSERM infectious diseases lab in France. Their tests showed that our nano-vaccine is at least as effective as Pfizer’s vaccine.”

Aside from its value to developing countries, Satchi-Fainaro said the plug-and-play technology provides a platform enabling scientists to synthesize more effective and affordable vaccines for future pandemics.

“[The technology] can train the immune system to fight cancer or infectious diseases like Covid-19. We are currently expanding its use to target a range of additional diseases, enabling the rapid development of relevant new vaccines when needed,” she said.

The research has received grants from the Israel Innovation Authority and Merck under the Nofar program, as well as funding from Spain’s La Caixa Foundation Impulse as an accelerated program, and support from the ISIDORe feasibility program.

It is also part of a broader vaccine platform development program at Satchi-Fainaro’s lab, supported by a European Research Council Advanced Grant.


TOPICS: Business/Economy; Health/Medicine; Science
KEYWORDS: covid19; israel; qvirus; vaccine
Navigation: use the links below to view more comments.
first 1-2021-4041-6061-65 next last

1 posted on 11/25/2024 1:13:45 PM PST by nickcarraway
[ Post Reply | Private Reply | View Replies]

To: nickcarraway

“The breakthrough vaccine trains the immune system against all common Covid-19 variants with the same efficiency as existing vaccines.”

LOL


2 posted on 11/25/2024 1:14:54 PM PST by goodnesswins (Don’t be REALITY PHOBIC!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway
heir tests showed that our nano-vaccine is at least as effective as Pfizer’s vaccine.

Not exactly a powerful marketing slogan.

3 posted on 11/25/2024 1:15:48 PM PST by Tell It Right (1 Thessalonians 5:21 -- Put everything to the test, hold fast to that which is true.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

Give it to Bill Gates!


4 posted on 11/25/2024 1:16:26 PM PST by Thank You Rush
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

5 posted on 11/25/2024 1:17:21 PM PST by stars & stripes forever (Blessed is the nation whose GOD is the LORD. (Psalm 33:12))
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

They can KMA with their nano tech.


6 posted on 11/25/2024 1:17:27 PM PST by philman_36 (Pride breakfasted with plenty, dined with poverty and supped with infamy. Benjamin Franklin)
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway
The breakthrough vaccine trains the immune system against all common Covid-19 variants with the same efficiency as existing vaccines.

So it doesn't work either.

This hyper fixation on what is now a fairly minor virus is creepy. If this was really doable why don't we have a vax for the common cold? Or one that works on all flu variants instead of 10% (at best)?

7 posted on 11/25/2024 1:18:20 PM PST by ChildOfThe60s ("If you can remember the 60s....you weren't really there")
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

Still not getting it.


8 posted on 11/25/2024 1:18:46 PM PST by hdbc
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

with the same efficiency as existing vaccines............SRRT..........


9 posted on 11/25/2024 1:19:01 PM PST by Red Badger (Homeless veterans camp in the streets while illegals are put up in 5 Star hotels....................)
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

10 posted on 11/25/2024 1:19:33 PM PST by Allegra (Deplorable garbage)
[ Post Reply | Private Reply | To 1 | View Replies]

To: goodnesswins
The breakthrough vaccine trains the immune system against all common Covid-19 variants with the same efficiency as existing vaccines.

In other words, with the same efficiency as powdered sugar.

11 posted on 11/25/2024 1:20:37 PM PST by HartleyMBaldwin
[ Post Reply | Private Reply | To 2 | View Replies]

To: stars & stripes forever

Horse paste works great except for a craving for carrots and sugar cubes.


12 posted on 11/25/2024 1:21:58 PM PST by bray (It's not racist to be racist against races the DNC hates.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: nickcarraway

Still no.


13 posted on 11/25/2024 1:22:22 PM PST by VTenigma (Conspiracy theory is the new "spoiler alert")
[ Post Reply | Private Reply | To 1 | View Replies]

To: HartleyMBaldwin
In other words, with the same efficiency as powdered sugar.

Or a Timber Rattler.

14 posted on 11/25/2024 1:23:37 PM PST by gitmo (If your theology doesn’t become your biography, what good is it?)
[ Post Reply | Private Reply | To 11 | View Replies]

To: ChildOfThe60s
So it doesn't work either.

Hey, they said “efficiency,” not “efficacy.”

15 posted on 11/25/2024 1:26:45 PM PST by gundog (It was a bright cold day in April, and the clocks were striking thirteen. )
[ Post Reply | Private Reply | To 7 | View Replies]

To: nickcarraway

Are the nano-particles as unnecessarily invasive, more unnecessarily invasive or less unnecessrily invasive than the mRNA sequences in the other Covid vaccines??


16 posted on 11/25/2024 1:27:12 PM PST by Wuli
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

This one couple I know have had every vaccine and they keep getting covid. They literally avoid gatherings because they are scared of getting it again. She is a nurse and and when we first met three years ago she was lecturing me for refusing to get jabbed. I told her if I get covid I would just get some Ivermectin ect... She laughed at me and started making fun of the horse paste. I don’t know how many rounds of shots they have had since then, but I still have yet to get covid and they can’t meet us for dinner because they are too scared to go out.


17 posted on 11/25/2024 1:29:24 PM PST by TBall
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

They’re bound and determined they are gonna get that shit in everybody’s body one way or another


18 posted on 11/25/2024 1:29:47 PM PST by V_TWIN (America...so great even the people that hate it refuse to leave!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ChildOfThe60s

Why no protection against corona virus 1 - coronavirus 18?

Or SARS 1?


19 posted on 11/25/2024 1:32:37 PM PST by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
[ Post Reply | Private Reply | To 7 | View Replies]

To: nickcarraway

We’re all about to get crop dusted!-(


20 posted on 11/25/2024 1:32:43 PM PST by Harpotoo (Being a socialist is a lot easier than having to WORK like the rest of US:-))
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-4041-6061-65 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson