Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Telltale amino acid deficiencies may hold the key to new treatments for long COVID, say researchers
Medical Xpress / University of Alberta / Frontiers in Immunology ^ | Feb. 8, 2024 | Gillian Rutherford / Suguru Saito et al

Posted on 02/11/2024 2:07:56 PM PST by ConservativeMind

A research team brings together experts in an effort to discover exactly what is ailing the sickest long COVID patients and find treatments for them.

The team reports that a disproportionate number of people affected—nearly 70%—are female and face debilitating symptoms that are identical to chronic fatigue syndrome, now referred to as myalgic encephalomyelitis/chronic fatigue syndrome or ME/CFS. Blood samples show telltale amino acid deficiencies, suggesting readily available supplements have potential as therapy.

"We do not actually believe that long COVID is a separate new disease," explains Jan Willem Cohen.

Thirty patients had persistent severe long COVID symptoms 12 months after their acute infection that met the criteria for a ME/CFS diagnosis.

Analysis showed that all of the people who had acute COVID exhibited some changes, but the 30 long COVID patients exhibited several persistent metabolomic abnormalities 12 months after their acute illness.

The first change the researchers noted was abnormally low levels of adenosine triphosphate (ATP), which is the cellular source of energy, likely due to mitochondrial dysfunction caused by the disease.

Next, the team noted signs of chronic systemic inflammation, including finding markers of compromised gut integrity resulting in gut products leaking into the blood—a problem often observed in patients with HIV.

Finally, the researchers noted significantly lower-than-normal levels of the amino acids sarcosine, glutamine and serine in the plasma of the long COVID patients. All three are associated with normal brain function. Sarcosine is used as a supplement to treat depression and schizophrenia, low glutamine can cause the gut to leak, and low serine is associated with seizures and learning difficulties.

Strikingly, the team found that long COVID patients with lower plasma levels of these amino acids were more likely to report symptoms of clinical depression, anxiety and mental impairment.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: calcification; covid; eaglesyndrome; glutamine; longcovid; neck; neckpain; sarcosine; serine; treatment; virus
“…the researchers noted significantly lower-than-normal levels of the amino acids sarcosine, glutamine and serine in the plasma of the long COVID patients.”

“Blood samples show telltale amino acid deficiencies, suggesting readily available supplements have potential as therapy.”

Sarcosine, glycine, and glutamine are all available as supplements from websites like Amazon and Walmart.

I take 1,200 mg of glycine a day and used to take glutamine when doing serious weight workouts. Sarcosine is available, but I have never used it, but it is a byproduct of metabolizing choline, which we get from egg yolks.

It likely wouldn’t take much of any of these to see if they can help someone with long COVID, or even possibly Chronic Fatigue Syndrome, which the researchers believe is potentially the same condition.

1 posted on 02/11/2024 2:07:56 PM PST by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 02/11/2024 2:08:37 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

If we would just nuke China from space while all of WHO and Fauci are attending a meeting in that country, we likely would end up with a lot less of these man-made viruses damaging and destroying life on the planet.


3 posted on 02/11/2024 2:10:13 PM PST by CatOwner (Don't expect anyone, even conservatives, to have your back when the SHTF in 2021 and beyond.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Who else believes that “long covid” is actually the persistent symptoms that people have experienced with colds, flu, and other maladies over the ages? Covid mythology has replaced so very much science.


4 posted on 02/11/2024 2:13:35 PM PST by jimfree (My 21 y/o granddaughter continues to have more quality exec experience than Joe Biden.)
[ Post Reply | Private Reply | To 2 | View Replies]

To: ConservativeMind

Many fitness people have a cocktail of glutamine(single amino), creatine, and BCAAs post lifting.


5 posted on 02/11/2024 2:23:20 PM PST by EEGator
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Infections can sometimes kick in chronic auto-immune problems.

Flu, cold, Covid (which is a type of cold virus).


6 posted on 02/11/2024 2:25:27 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
[ Post Reply | Private Reply | To 1 | View Replies]

To: jimfree

Well, it sounds like they have a very scientific name for, “women who are always tired.”


7 posted on 02/11/2024 2:27:58 PM PST by Empire_of_Liberty
[ Post Reply | Private Reply | To 4 | View Replies]

To: ConservativeMind

I will give a hint to some of you here who are suffering from what you think is long covid. Ask for a copy of your panoramic Xray from your dentist and make sure you don’t have Eagle syndrome. Many Doctors and Dentists have never heard of it but you can see it on the Xray for many people who have it.

I would also say anyone with tinnitus should also look.


8 posted on 02/11/2024 3:21:08 PM PST by RummyChick
[ Post Reply | Private Reply | To 1 | View Replies]

To: RummyChick
this can screw you up in so many ways that you can't even believe. doctors don't understand it. Very few Doctors really know how to treat it. And symptoms can be like long Covid. It could have been causing you a problem for a long time without your realizing it as the source but once your Vagus nerve got damaged from Covid it could have all gone to hell



9 posted on 02/11/2024 3:26:29 PM PST by RummyChick
[ Post Reply | Private Reply | To 8 | View Replies]

To: RummyChick

there are some long covid therapies that work the vegus nerve.


10 posted on 02/12/2024 5:22:25 AM PST by ckilmer
[ Post Reply | Private Reply | To 9 | View Replies]

To: jimfree

Call it a coincidence. Long covid sufferers all seem to be vaxed. Perchance, the name should be changed to long vaxed sufferers.


11 posted on 02/12/2024 8:42:53 AM PST by foundedonpurpose (Praise Hashem, for his restoration of all things! )
[ Post Reply | Private Reply | To 4 | View Replies]

To: ConservativeMind

IF a person gets Shingles, L-Lysine helps ALOT with the nerve pain.


12 posted on 02/12/2024 10:19:50 AM PST by ridesthemiles
[ Post Reply | Private Reply | To 1 | View Replies]

To: RummyChick

Bkmk Eagle


13 posted on 02/13/2024 1:43:29 PM PST by ptsal (Vote R.E.D. >>>Remove Every Democrat ***)
[ Post Reply | Private Reply | To 8 | View Replies]

To: CatOwner

The only way to be sure


14 posted on 02/13/2024 1:46:45 PM PST by combat_boots
[ Post Reply | Private Reply | To 3 | View Replies]

To: ptsal

the wild thing about Eagle Syndrome is that when you start researching it you will see ancient skulls with the issue but no one figured out the problem until 1937.

I saw a skull from the late holocene era which is the Ice Age.

and yet even today...most doctors and dentists dont have a clue. The support group forum for Eagle syndrome is pretty horrifying over what these people have been through to get diagnosed.


15 posted on 02/13/2024 4:38:02 PM PST by RummyChick
[ Post Reply | Private Reply | To 13 | View Replies]

To: RummyChick

Thanks for the response


16 posted on 02/14/2024 6:17:07 PM PST by ptsal (Vote R.E.D. >>>Remove Every Democrat ***)
[ Post Reply | Private Reply | To 15 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson