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Ivermectin as a SARS-CoV-2 Pre-Exposure Prophylaxis Method in Healthcare Workers: A Propensity Score-Matched Retrospective Cohort Study [Published August 26,2021]
CUREUS ^ | 08/26/2021 | Morgenstern et al

Posted on 08/26/2021 10:01:05 PM PDT by SeekAndFind

Abstract

Background: Ivermectin is a drug that has been shown to be active against coronavirus disease 19 (COVID-19) in previous studies. Healthcare personnel are highly exposed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Therefore, we decided to offer them ivermectin as a pre-exposure prophylaxis (PrEP) method.

Purpose: Primary outcome was to measure the number of healthcare workers with symptomatic SARS-CoV-2 infection and a positive reverse transcription polymerase chain reaction (RT-PCR) COVID-19 test in the ivermectin group and in the control group. Secondary outcome was to measure the number of sick healthcare workers with a positive RT-PCR COVID-19 test whose condition deteriorated and required hospitalization and/or an Intensive Care Unit (ICU), or who died, in the ivermectin group and in the control group.

Material and methods: This observational and retrospective cohort study was carried out in two medical centers, Centro Medico Bournigal (CMBO) in Puerto Plata and Centro Medico Punta Cana (CMPC) in Punta Cana, Dominican Republic. The study began on June 29, 2020, and ended on July 26, 2020. A Statistical Package for Social Sciences (SPSS) Propensity Score Matching procedure was applied in a 1:1 ratio to homogeneously evaluate 271 healthcare personnel that adhered to a PrEP program with ivermectin at a weekly oral (PO) dose of 0.2 mg/kg, and 271 healthcare personnel who did not adhere to the program were assigned as a control group.

Results: In 28 days of follow-up, significant protection of ivermectin preventing the infection from SARS-CoV-2 was observed: 1.8% compared to those who did not take it (6.6%; p-value = 0.006), with a risk reduction of 74% (HR 0.26, 95% CI [0.10,0.71]).

Conclusions: These results suggest that compassionate use of weekly ivermectin could be an option as a preventive method in healthcare workers and as an adjunct to immunizations,

(Excerpt) Read more at cureus.com ...


TOPICS: Health/Medicine; Science; Society
KEYWORDS: ivermectin; prophylaxis; sarscov2
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To: mac_truck

The PCR test that cannot differentiate between “covid,” the flu and the common cold, which is being recalled by the CDC, can detect variants?


81 posted on 09/11/2021 2:40:05 PM PDT by wastedyears (The left would kill every single one of us and our families if they knew they could get away with it)
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To: Candor7

Thank You. . . will pass along.


82 posted on 09/12/2021 4:51:07 AM PDT by adc (wethepeople)
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To: eartick
Covid’s Willing Executioners How have previously normal people become so eager to deal out death in judgment?
83 posted on 09/12/2021 4:56:14 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: adc

You are most welcome. We do not have much time before people realize that the boosters and vaccines do not work as advertised.Only very limited immnnnity. To be immune you have to catch it andrecover, and so Ivermectin therapy is one good answer, treat the Covid as if it were malaria. Get the pills to everyone along with education on how to use them properly.

Additionally IVM will likely clear the body of vaccine induced stick protiens that are not healthy for heart nor blood clot friendly.


84 posted on 09/12/2021 4:56:28 AM PDT by Candor7 ((Obama Fascism:http://www.americanthinker.com/2009/05/barack_obama_the_quintessentia_1.html) )
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To: LilFarmer
They started ivermectin in the middle of that wave and their cases went from 414,000 cases and 4,000 deaths per day to almost zero in FIVE WEEKS

The Indian government approved limited use of Ivermectin for mild cases and HCQ to healthcare workers exposed to Covid patients just as the delta wave peaked, with no research studies to support their decision.

This is in line with American drug maker Merck's statement that they found

~No scientific basis for a potential therapeutic effect against COVID-19 from pre-clinical studies;
~No meaningful evidence for clinical activity or clinical efficacy in patients with COVID-19 disease,
~A concerning lack of safety data in the majority of studies.

Suggesting ivermectin was the reason the delta wave in India subsided, is very much like suggesting wearing a mask stops the spread of the virus. You'd like to believe it, but hard science doesn't back you up.

85 posted on 09/12/2021 7:16:25 AM PDT by mac_truck (aide toi et dieu t'aidera)
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To: wastedyears
The PCR test that cannot differentiate between “covid,” the flu and the common cold, which is being recalled by the CDC, can detect variants?

No...the Roche variant test is a viral DNA analysis used in research around the country by laboratories engaged in genomic surveillance of Covid-19.

I gave you a link, why don't you sober up and read it?

86 posted on 09/12/2021 7:24:07 AM PDT by mac_truck (aide toi et dieu t'aidera)
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To: mac_truck

**** The Indian government approved limited use of Ivermectin for mild cases and HCQ to healthcare workers exposed to Covid patients just as the delta wave peaked, with no research studies to support their decision.****

There is plenty of research to support the efficacy of ivermectin, much of which was available before India used it. https://ivmmeta.com/

**** This is in line with American drug maker Merck’s statement that they found...****

Merck has teamed up with Pfizer for a new drug to fight covid https://news.yahoo.com/pfizer-starts-dosing-patients-oral-121106516.html

The new drug they are producing is a protease inhibitor just like ivermectin.

Pfizer covid pill protease inhibitor:
https://www.pfizer.com/news/press-release/press-release-detail/pfizer-initiates-phase-1-study-novel-oral-antiviral

Ivermectin protease inhibitor: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7996102/

https://citizenfreepress.com/breaking/pfizers-new-pill-to-fight-covid-utilizes-a-protease-inhibitor-ivermectin-is-also-a-protease-inhibitor/

Why would Pfizer, Merck et al, make a new drug that works just like ivermectin when one already exist? Because there is no money to be made in ivermectin as it’s patent expired in 1996.


87 posted on 09/12/2021 7:39:34 AM PDT by LilFarmer
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To: LilFarmer
Why would Pfizer, Merck et al, make a new drug that works just like ivermectin when one already exist?

Because Ivermectin by itself just isn't effective, and drug makers are in business to make money.

88 posted on 09/12/2021 8:24:12 AM PDT by mac_truck (aide toi et dieu t'aidera)
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To: mac_truck

*****Because Ivermectin by itself just isn’t effective******

No drug is 100% effective.

Again, here are 63 studies that show it is at least 86% effective as a prophylactic and 70% effective in early treatment.
https://ivmmeta.com/

If it wasn’t effective, Pfizer and Merck wouldn’t be duplicating it in their new pill.


89 posted on 09/12/2021 8:39:09 AM PDT by LilFarmer
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To: LilFarmer
If it wasn’t effective, Pfizer and Merck wouldn’t be duplicating it in their new pill.

They're not...and you should spend more time reading your own links

90 posted on 09/12/2021 8:54:28 AM PDT by mac_truck (aide toi et dieu t'aidera)
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To: mac_truck

What test is the CDC recalling due to its incredibly poor ability to detect something in particular?


91 posted on 09/12/2021 4:53:17 PM PDT by wastedyears (The left would kill every single one of us and our families if they knew they could get away with it)
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