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Monulparivir, the drug that "completely" stops the spread of coronavirus in 24 hours: This antiviral drug could prevent virus carriers from developing severe symptoms and transmitting the disease in a single day, according to studies.
Entrepreneur ^ | 12/06/2020

Posted on 12/06/2020 10:01:01 PM PST by SeekAndFind

This article was translated from our Spanish edition using AI technologies. Errors may exist due to this process.

The COVID-19 vaccine may spell the end of the pandemic, but while mass vaccination is not available it is vital to stop community transmission. The new antiviral drug MK-4482 / EIDD-2801 or Molnupiravir, has managed to suppress "completely" the transmission of the coronavirus in just 24 hours , according to studies by the Institute of Biomedical Sciences of Georgia State University.

"This is the first demonstration of an orally available drug that quickly blocks the transmission of SARS-CoV-2 , so it could be a game changer," the researchers explained in the work published in the journal Nature Microbiology .

The antiviral drug was developed at Emory University in Atlanta by the drug innovation company Drug Innovation Ventures at Emory (DRIVE), which was licensed by Ridgeback Biotherapeutics, which partnered with Merck & Co. Molnupiravir was originally designed to treat the flu and prevent the virus from making copies of itself, creating errors during viral RNA replication.

The experts detail that tests were carried out on ferrets and it was observed that they presented a reduction in the amount of viral particles. Then those ferrets were put with others that had not been treated. None of the ferrets in the second group became infected with COVID-19.

"We believe that ferrets are a relevant transmission model because they easily spread SARS-CoV-2, but for the most part they do not develop a serious disease, which is very similar to the spread of SARS-CoV-2 in young adults," he said. Dr. Robert Cox, a postdoctoral fellow in the Plemper group and co-lead author of the study.

“We observed early on that MK-4482 / EIDD-2801 has broad spectrum activity against respiratory RNA viruses and that oral treatment of infected animals with the drug reduces the amount of viral particles spread by several orders of magnitude, drastically reducing transmission. These properties made MK-4482 / EIDD / 2801 a powerful candidate for the pharmacological control of Covid-19 ”, the report adds.

A promising antiviral that breaks the chain of transmission:

Therapeutic treatment of animals infected with MK-4482 / EIDD-2801 reduces the burden of SARS-CoV-2 in the upper respiratory tract and completely suppresses the spread in ferrets. https://t.co/WaMnNk6aao - José Manuel Bautista (@ 1000genes)December 5, 2020

If this ferret-based data is translated into humans, Covid-19 patients treated with the drug could become non-infectious within 24 hours of starting treatment.

The drug can be taken orally, and treatment can be started early for a triple potential benefit: inhibiting patients' progress to severe disease, shortening the infectious phase to alleviate the emotional and socioeconomic cost of prolonged patient isolation, and containing quickly local outbreaks.

Molnupiravir is currently in advanced phase II / III clinical trials. It is being tested in three different doses every 12 hours for five days in patients with SARS-CoV-2.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: antiviral; chinavirustreatment; clinicaltrials; coronavirus; covid19; covidcure; monulparivir
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To: greeneyes
greeneyes :" I like the sounds of this better than the vaccine."

All vaccines have some side effects.
It will be interesting to see if this medication, when used on human volunteers,
has any side effects or concerns.

41 posted on 12/07/2020 8:23:27 PM PST by Tilted Irish Kilt
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To: FreedomPoster

it’s claimed to be much much better- hopefully it lives up to it’s name, but I suspect it won’t be available here anytime soon- it would mean an end to the unconstitutional lockdowns, and liberals won’t stand for that


42 posted on 12/07/2020 9:27:06 PM PST by Bob434
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To: FreedomPoster

Thanks for the link. I had an initial protocol based on the Dr. that was giving the MedCram videos and later printed a copy of the Zelenko (sp?)protocol to compare.

I printed a 2 pg summary of the EVMS protocol and saved the links to my notes on WuHuFlu.


43 posted on 12/07/2020 9:30:13 PM PST by greeneyes ( Moderation In Pursuit of Justice is NO Virtue--LET FREEDOM RING)
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To: greeneyes

Related link you might want:

https://ivmmeta.com/


44 posted on 12/08/2020 12:09:45 AM PST by FreedomPoster (Islam delenda est)
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To: Tilted Irish Kilt

Thanks for the ping.


45 posted on 12/08/2020 7:54:29 AM PST by GOPJ (Joseph Stalin:"Those who cast the votes decide nothing. Those who count the votes decide everything.)
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To: null and void
Quarantine the sick. Protect the vulnerable. Free everyone else.

Everyday that goes by that makes more sense...

46 posted on 12/08/2020 7:55:48 AM PST by GOPJ (Joseph Stalin:"Those who cast the votes decide nothing. Those who count the votes decide everything.)
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To: GOPJ

In practice it’s more like:

Put the infectious with the vulnerable. Release the guilty from prison. Put the innocent in solitary lockdown.


47 posted on 12/08/2020 7:59:01 AM PST by null and void (My President is a Person Of Color, Orange is a Color...)
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To: null and void
Put the infectious with the vulnerable. Release the guilty from prison. Put the innocent in solitary lockdown.

Whoa... getting a little cynical there null? /s

(sadly, you're right again)

48 posted on 12/08/2020 8:09:38 AM PST by GOPJ (Joseph Stalin:"Those who cast the votes decide nothing. Those who count the votes decide everything.)
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To: GOPJ

Not getting, been that way since I woke up in high school...


49 posted on 12/08/2020 8:14:12 AM PST by null and void (My President is a Person Of Color, Orange is a Color...)
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To: Bob434; null and void; All

Will it be significantly cheaper than Remdesivir which is reported to cost around $3,000 a treatment course for various insurance programs. On the other hand it appears this can be used pre hospital like Dr. Zelenko’s 3 part protocol which costs $20 for 5 days of medication.


50 posted on 12/08/2020 11:48:00 AM PST by gleeaikin
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To: FreedomPoster

Thanks. Printed hard copy and saved link.


51 posted on 12/08/2020 4:41:22 PM PST by greeneyes ( Moderation In Pursuit of Justice is NO Virtue--LET FREEDOM RING)
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Bookmark


52 posted on 12/08/2020 7:25:09 PM PST by DocRock (And now is the time to fight! Peter Muhlenberg)
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To: Bob434; SeekAndFind; null and void; JimRed; gas_dr; Troublemaker; Mom MD; All

Here is a youtube video of a California doctor who has had great success using HCQ, zinc, and Azithromycin or Doxycycline. Notice how he almost seems afraid to mention the zinc. And like everyone else fails to emphasize it is the zinc that kills the virus in the infected cells. The HCQ just helps the zinc get inside cells. HCQ is known as an IONOPHORE. I have heard of at least 6 ionophores that can help mobilize the virus killer ZINC. I only know of one other virus killer used successfully in this way. That is the HIV antiviral medicine Kaletra. It was used very early last Spring by the South Koreans along with HCQ to bring down their Covid infection levels very quickly. Dr. Zelenko obtained information from both Korea and France when developing his 3 part protocol.

https://www.youtube.com/watch?v=PE3QfTnIazU

A second very informative link is the one below listing over 200 links covering the fight by Dr. Zelenko and others to bring this low cost successful treatment to the world. It also shows the many efforts to “prove” it does NOT work, and other efforts to censor any mention of this on public media. On at least 6 occasions AOL news stories have blocked my comments discussing these treatments in a scientific way by saying I was violating their “Community Standards”. At the same time AOL was not censoring vicious, ugly comments about Trump and Biden at the same news articles.

https://faculty.utrgv.edu/eleftherios.gkioulekas/zelenko/index.html


53 posted on 12/08/2020 11:03:24 PM PST by gleeaikin
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To: gleeaikin

HcQ and azithromycin was a very rough and first treatment. Clinging to this is somewhat like clinging to vinyl records. It is not as useful as later treatments.

The current and best treatment is ivermectin, doxycycline, simvastatin, Pepcid.

Hcq is probably a useful prophylactic. As for vitamin C D and zinc I have become convinced we should be taking these supplementally each day. But the repeated hammering away at ionophores and infatuation with it is not really all that relevant anymore.


54 posted on 12/09/2020 4:29:37 AM PST by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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To: gas_dr

For prophylaxis though,, Where to get ivermectin? Docs i think don’t like prescribing 9ff label use for prevention? Ordering from overseas is sketchy at best

Ivermectin does seem like best so far. There is spoked to be a new antiviral that is claim e d to be quite good. Can’t remember name now, begins with an m. But that seems a ways off.


55 posted on 12/09/2020 10:08:13 AM PST by Bob434
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To: gas_dr

Lol DOH, name of drug is subject of thread lol. Got my threads mixed up. Ugh, I’m not paying attention


56 posted on 12/09/2020 10:10:14 AM PST by Bob434
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To: SeekAndFind

bttt


57 posted on 12/09/2020 10:13:40 AM PST by linMcHlp
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To: LucyT

If it works, it’d be better than any vaccine. We’re hearing of serious complications from the vaccine.


58 posted on 12/09/2020 10:21:08 AM PST by bgill (.)
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To: Tilted Irish Kilt; SeekAndFind; null and void; All

I decided to check the name itself on Google. I found the link below but did not have time to read the comments. When I went back later I found this message. “Sorry, this post has been removed by the moderators of r/worldnews.
Moderators remove posts from feeds for a variety of reasons, including keeping communities safe, civil, and true to their purpose.” I don’t know if this was censorship or if they felt the headline did not match the data. The title said it “completely” stopped the virus in 24 hours. It did not include that this was solely based on ferrit’s exposure. The Comments are still there though.

https://www.reddit.com/r/worldnews/comments/k8en7v/monulparivir_the_drug_that_completely_stops_the/


59 posted on 12/09/2020 2:41:32 PM PST by gleeaikin
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To: chopperk; All

I agree, but think of all the poor Big Pharma employees and stockholders who wouldn’t be able to get a lot richer. /s


60 posted on 12/09/2020 2:46:06 PM PST by gleeaikin
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