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People With Blood Type A May Be More Vulnerable to coronavirus, China Study Finds
AsiaOne ^ | MARCH 17, 2020 | STEPHEN CHEN

Posted on 03/17/2020 5:00:00 PM PDT by nickcarraway

People with blood type A may be more vulnerable to infection by the new coronavirus, while those with type O seem more resistant, according to a preliminary study of patients in China who contracted the disease known as Covid-19.

Medical researchers in China took blood group patterns of more than 2,000 patients infected with the virus in Wuhan and Shenzhen and compared them to local healthy populations. They found that blood type A patients showed a higher rate of infection and they tended to develop more severe symptoms.

While the researchers said the study was preliminary and more work was needed, they did urge governments and medical facilities to consider blood type differences when planning mitigation measures or treating patients with the virus, known as Sars-CoV-2.

“People of blood group A might need particularly strengthened personal protection to reduce the chance of infection,” wrote the researchers led by Wang Xinghuan with the Centre for Evidence-Based and Translational Medicine at Zhongnan Hospital of Wuhan University.

“Sars-CoV-2-infected patients with blood group A might need to receive more vigilant surveillance and aggressive treatment,” Wang wrote.

In contrast, “blood group O had a significantly lower risk for the infectious disease compared with non-O blood groups”, according to a paper they published on Medrxiv.org on March 11.

Of 206 patients who had died from Covid-19 in Wuhan, 85 had type A blood, which was 63 per cent more than the 52 with type O. The pattern existed across different age and gender groups.

“It might be helpful to introduce ABO blood typing in both patients and medical personnel as a routine part of the management of Sars-CoV-2 and other coronavirus infections, to help define the management options and assess risk exposure levels of people,” Wang wrote in the paper.

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The study was conducted by scientists and doctors from cities across China including Beijing, Wuhan, Shanghai and Shenzhen. It has not been peer reviewed, and the authors cautioned that there could be risks involved in using the study to guide current clinical practice.

Gao Yingdai, a researcher with the State Key Laboratory of Experimental Haematology in Tianjin who was not involved in the study, said it could be improved with a larger sample size. Though 2,000 was not small, it is dwarfed by the total number of patients infected by the coronavirus, now at nearly 180,000 globally.

Another limitation of the study was that it did not provide a clear explanation about the phenomenon, such as the molecular interaction between the virus and different types of red blood cells, Gao said.

Blood types are determined by a so-called antigen, a material on the surface of red blood cells that can trigger an immune response. Austrian biologist Karl Landsteiner discovered the main blood groups in 1901, naming them type A, B, AB and O. The discovery allowed for safe blood transfusions by matching blood types in patients.

Blood types vary in a population. In the United States, about 44 per cent of the population is type O, while about 41 per cent is type A. In Wuhan, which has a population of about 11 million, type O is 32 per cent, while A is 34 per cent among healthy people. Among Covid-19 patients, it was about 38 and 25 per cent.

Scientists are still unsure how different blood groups evolved, though one theory is that they are a genetic memory of plagues. Others argue that environmental factors such as altitude, temperature or humidity might have played a role to favour the increase of certain blood type populations.

Blood type difference has been observed in other infectious diseases including Norwalk virus, hepatitis B and severe acute respiratory syndrome (Sars), according to previous studies.

Gao at the Tianjin lab said the new study “may be helpful to medical professionals, but ordinary citizens should not take the statistics too seriously”. “If you are type A, there is no need to panic. It does not mean you will be infected 100 per cent,” she said.

“If you are type O, it does not mean you are absolutely safe, either. You still need to wash your hands and follow the guidelines issued by authorities.”


TOPICS: Health/Medicine; Science
KEYWORDS: blood; bloodtype; bloodtypes; china; chinavirusinfo; coronavirus; sarscov2; typea; typeo
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To: hsmomx3

me too


41 posted on 03/17/2020 5:22:44 PM PDT by longfellowsmuse (last of the living nomads)
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To: nickcarraway
I read once that Wales had the highest incidence of O type blood than anywhere else in the world.

I must have read it in this book:

The Origins of the British: A Genetic Detective Story


42 posted on 03/17/2020 5:23:20 PM PDT by blam
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To: nickcarraway
A - for me. I will always remember that because I got hauled out of bed in the middle of the night during basic training at Lackland and provided the opportunity to volunteer to give blood to another basis trainee who got into a car accident and needed transfusions.

As I recall, we all volunteered. Nobody even asked how some basic trainee got into a car accident.

43 posted on 03/17/2020 5:23:51 PM PDT by Bernard ("I don't know if that's true:" Schiff said.)
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To: nickcarraway; All

I used to be O+ and then I had a bone marrow transplant to treat my leukaemia.

Now my blood type is O-


44 posted on 03/17/2020 5:24:21 PM PDT by airborne (I don't always scream at the TV but when I do it's hockey season!)
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To: nickcarraway

A- here ... sigh.


45 posted on 03/17/2020 5:27:29 PM PDT by RightField
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To: airborne

You have just answered the question that has always bothered me, if a person has a bone marrow transplant, does his blood type change to the donor’s blood type. It would make a great suspense/who done it movie!


46 posted on 03/17/2020 5:27:31 PM PDT by smvoice (I WILL NOT WEAR THE RIBBON.)
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To: mware
A+ here.

And here.

It's not fair, I get an A+ in something and this is my reward???

HARumph!

47 posted on 03/17/2020 5:28:19 PM PDT by null and void (By the pricking of my lungs, Something wicked this way comes ...)
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To: mware

Same here — A+


48 posted on 03/17/2020 5:29:15 PM PDT by Polyxene (Out of the depths I have cried to Thee, O Lord; Lord, hear my voice.)
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To: nickcarraway

I’m type O. Husband and kids are type A.

Wonder if blood type also impacts susceptibility to influenza. . About 10 years ago my family went down like dominoes with influenza. I’m the only one who didn’t catch it and believe me, I was up close and caring for five people with it. I kissed the foreheads of sick kids, cradled them in my arms, handled all their dishes and laundry yet never caught it. Six people in a small house meant very close quarters.

Hopefully, no one in my family catches this; especially our son with severe asthma. He works in a hospital so I pray for his protection. Our youngest son also has asthma, but not as severe and he is only 9. It seems this doesn’t affect children as much.


49 posted on 03/17/2020 5:30:28 PM PDT by NorthstarMom
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To: blam
I thought I ought to look it up.....look what I found:

Blood type distribution by country

50 posted on 03/17/2020 5:32:37 PM PDT by blam
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To: nickcarraway

Uh oh.


51 posted on 03/17/2020 5:37:32 PM PDT by libertylover (Socialism will always look good to those who think they can get something for nothing.)
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To: nickcarraway

I’m toast too.


52 posted on 03/17/2020 5:45:24 PM PDT by toast
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To: nickcarraway

Eh - Blood types are genetic. Type A is dominant over O, and the cases of Coronavirus in China were primarily limited to Wuhan province where most likely generations of families have lived. Also, the majority ABO type nationwide in China is A Pos - I’m not convinced.


53 posted on 03/17/2020 5:46:42 PM PDT by Shethink13 (there are 0 electoral votes in the state of denial)
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To: nickcarraway

Stat question...

How many in the general population would have to be randomly sampled before you could extrapolate a general population infection number???


54 posted on 03/17/2020 5:54:07 PM PDT by gov_bean_ counter (AOC the bartender would have had to work on the second floor at Miss KittyÂ’s saloon...)
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To: nickcarraway

“...They found that blood type A patients showed a higher rate of infection...”

Are democrats type A’s?


55 posted on 03/17/2020 6:20:38 PM PDT by Bonemaker (invictus maneo)
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To: nickcarraway
Well, I'm dead.

A2+ and damaged lungs.

It was nice knowing you!

56 posted on 03/17/2020 6:21:59 PM PDT by Harmless Teddy Bear (A hero is a hero no matter what medal they give him. Likewise a schmuck is still a schmuck.)
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To: nickcarraway

Great. Me and my husband (and ostensibly, our son), exact same A+.


57 posted on 03/17/2020 6:25:27 PM PDT by the OlLine Rebel (Common sense is an uncommon virtue./Federal-run medical care is as good as state-run DMVs)
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To: All

“Relationship between the ABO Blood Group and the COVID-19 Susceptibility”

- see https://www.medrxiv.org/content/10.1101/2020.03.11.20031096v1


58 posted on 03/17/2020 6:25:54 PM PDT by Fury
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To: blam

Bookmark

I’ve traced my direct genealogy through numerous royal bloodlines, roman emperors and byzantine rulers.


59 posted on 03/17/2020 6:30:26 PM PDT by maggief
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To: mewzilla

Sorry - did not see you posted the link already.


60 posted on 03/17/2020 6:31:31 PM PDT by Fury
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