Posted on 01/21/2020 1:10:16 PM PST by SeekAndFind
Scientists have discovered a new cell in the immune system that can kill many types of cancer, which they hope could one day be used to create a "one size fits all" treatment for the disease.
In mice experiments and in lab dishes, the team showed that a new type of what are known as T-cells could detect a range of cancerous cells, while differentiating them from healthy cells.
A T-cell is a type of white blood cell in the immune system, which both helps to fight off infections as well as cancers. These new T-cells and their special receptors can home in on and kill lung, skin, leukemia, colon, breast, prostate, bone, kidney, cervical, and ovarian cancers. The researchers published their findings in the journal Nature Immunology.
The team believes the receptors on the T-cells are able to detect cancer through their interaction with a molecule called MR1, which is present on the surface of all human cells. The researchers believe MR1 may be signaling the compromised metabolism of the cell to the T-cell receptors.
Study co-author Garry Dolton told BBC News: "We are the first to describe a T-cell that finds MR1 in cancer cells—that hasn't been done before, this is the first of its kind."
Lead author of the study, professor Andrew Sewell of the Division of Infection and Immunity at Cardiff University, U.K., told Newsweek the team identified the cell after examining samples from a blood bank.
"We were looking for something else! All the best scientific discoveries are made by mistake," said Sewell.
Sewell told The Telegraph: "This was a serendipitous finding, nobody knew this cell existed. Our finding raises the prospect of a 'one-size-fits-all' cancer treatment, a single type of T-cell that could be capable of destroying many different types of cancers
(Excerpt) Read more at newsweek.com ...
Well . . . this would be great. I’ll wait to see what a reliable source other than Newsweak has to say.
ABSTRACT:
https://www.nature.com/articles/s41590-019-0578-8
Courtesy of Dead Corpse ....................
Dead Corpse
I meant see Dead Corpse’ link t the scientific paper..................
I believe the movie “I am Legend” started off somewhat like this. Spoiler alert -—> Zombie Apocalypse.
Discover New Immune Cell By Accident . . .
All the best scientific discoveries are made by mistake,”
= = =
Doesn’t this prove evolution?
We are all an evolved mistake?
I’ve believed that your body has had the ability to heal itself of cancer cells for a long while. Mutations of cells happen quite often, but most of the time, your body detects the mutated cancer cell and kills it before it can form anything more than a few cells.
I kinda doubt it. The Cancer Cure Industry has nothing to gain by a cure. Big Pharma and the AMA won’t allow it to happen.
There’s plenty of other diseases that will cost a fortune to treat..................
Not quite by accident. It was a screening looking for certain protein receptor sites in melanoma cells. The essay pointed out a certain t-cell that could be modified and introduced to a host that would trigger a certain protein and shut down the malignant cell.
So... A bit more like playing Scrabble and spelling out “to be or not to be” from your random pick pile.
No it doesn’t bob, put the doobie down.
Cancer immunology is extremely interesting. The most aggressive and lethal cancers (such as pancreatic, glioblastomas and others) have developed sophisticated tumor defensive mechanisms ( cytokines emitted by and surface proteins on the tumor cells) that prevent the body’s afferent and efferent immune modalities from first processing the tumor antigens and then destroy the tumor cells. The key to finding an immunological cure for cancer is to develop a strategy to overcome these tumor defense mechanisms that frustrate the body’s immune system.
The wet blanket crowd doesn’t like to hear that.
You are so far over this engineer’s head.
From Newsweek? Sorry if I don’t buy into the crap they spew! Fenbendazole Has been shown as a great cancer erradicator and tumor killer. People with stage 4 cancer, have been saved by buying a dog deworming medicine - cost $50 a month.
Exactly. This sounds like by modifying a t-cell, they can get it to trigger the MR5 protein receptor effectively shutting down the malignant cell. Using it’s own defenses against itself.
Unless I completely misread the abstract. Which, is entirely possible.
Panacur-C as well as every other OTC form of fenbendazole has practically disappeared, too. Too many people buying the stuff for cancer, or drug companies intentionally constraining supply?
Not so hard to understand. If the immune system is to destroy something alien and destructive ( which cancer cells are), first the immune system must take a bite of the cancer cells to begin processing them. This is done by the dendritic cells which phagocyte ( swallow) the tumor antigen . This is the afferent part of the immune response. The dendritic cells then deliver the antigen to lymph nodes where the antigens are processed and killer T cells, specifically programmed to kill those invading cells are produced and unleashed against them. This is the efferent part of the immune response and if successful destroys the invading alien cells. As mentioned before the most lethal and aggressive tumors have developed protective mechanisms that thwart both the afferent and efferent arms of the immune system. Have done a lot of thinking on how those tumor defense mechanisms may be overcome.
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