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Excessive brain activity linked to a shorter life
Greenwich Time ^ | 17 Oct 2019 | Carolyn Y. Johnson

Posted on 10/17/2019 8:25:57 AM PDT by DUMBGRUNT

"The completely shocking and puzzling thing about this new paper is . . . [brain activity] is what you think of as keeping you cognitively normal. There's the idea that you want to keep your brain active in later life," said Michael McConnell, a neuroscientist at the Lieber Institute for Brain Development, who was not involved in the study. "The thing that is super unexpected is . . . limiting neural activity is a good thing in healthy aging. It's very counterintuitive."

One model, called "CRUNCH," tries to explain changes in patterns of brain activation with age. It says that when people attempt harder and harder tasks, more regions of their brain are activated, until they reach a crunch point where they run out of mental resources. Older people have an earlier crunch point and can't activate as many regions. Another, called "STAC," says older adults have natural variation in their basic scaffolding of natural cognitive resources, and those variations influence how and whether people can engage more neural regions when faced with difficult tasks.

(Excerpt) Read more at greenwichtime.com ...


TOPICS: Chit/Chat; Health/Medicine
KEYWORDS: brain
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This may be a good sign for me passing my father and mother with near 92 years each!!

No need to strain the brain and possibly damage the few resourses remaining.

Yet sometimes there no alternatives, currently setting up IP security cameras on the home network and this clearly makes my brain hurt! Be that as it may, last night I was able to see two skunks, a possum and a rafter of rabbits, all at the same time! Very enjoyable and eased my hurting brain.

1 posted on 10/17/2019 8:25:57 AM PDT by DUMBGRUNT
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To: DUMBGRUNT
TV will make you stupid, but immortal!................😃
2 posted on 10/17/2019 8:27:26 AM PDT by Red Badger (Against stupidity the gods themselves contend in vain...................)
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To: Red Badger

Me—————SAFE on first! WooHoo!


3 posted on 10/17/2019 8:29:50 AM PDT by rktman ( #My2ndAmend! ----- Enlisted in the Navy in '67 to protect folks rights to strip my rights. WTH?)
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To: DUMBGRUNT

I don’t care what he says, I ain’t voting Democrat. Take me now!


4 posted on 10/17/2019 8:30:12 AM PDT by Billthedrill
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To: DUMBGRUNT

Listen up everybody...stop thinking,


5 posted on 10/17/2019 8:30:32 AM PDT by Bonemaker (invictus maneo)
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To: DUMBGRUNT

I call CROCK !!


6 posted on 10/17/2019 8:31:01 AM PDT by BuffaloJack (Chivalry is not dead. It is a warriors code and only practiced by warriors.)
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To: rktman

There was a study a few years back that determined Couch Potatoes lived longer!.....................


7 posted on 10/17/2019 8:31:55 AM PDT by Red Badger (Against stupidity the gods themselves contend in vain...................)
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To: DUMBGRUNT

I should see 150 easy


8 posted on 10/17/2019 8:32:57 AM PDT by Spruce
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To: Red Badger

That’s scary, this means the millennials might live even longer...


9 posted on 10/17/2019 8:32:58 AM PDT by Openurmind (The ultimate test of a moral society is the kind of world it leaves to its children. ~ D. Bonhoeffer)
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To: DUMBGRUNT

This must be peak “scientific” stupidity.

This is on the order of eating bugs and cannibalism.

The corporate media and compromised scientists are doing their best to confuse people and create fear.


10 posted on 10/17/2019 8:33:44 AM PDT by bkopto
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To: DUMBGRUNT

I have little to no problem complying with this health directive.


11 posted on 10/17/2019 8:35:24 AM PDT by The_Media_never_lie (Please, oh pretty please let Crazy Uncle Joe Biden be the nominee.)
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To: DUMBGRUNT

Well then it’s a good thing I have various methods to provide anesthesia to the brain. It helps slow my prought thocess.


12 posted on 10/17/2019 8:36:37 AM PDT by Starstruck (I'm usually sarcastic. Deal with it.)
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To: DUMBGRUNT

Read on - it appears to have nothing to do with choosing to think hard and/or long:

Researchers at Harvard Medical School analyzed brain tissue donated to human brain banks by people ranging in age from their 60s and 70s to centenarians who lived to be 100 or older. They found people who died before their mid-80s had lower levels in their brains of a protein called REST that tamps down genes involved in sparking brain activity, compared to the very oldest people. REST had already been shown to be protective against Alzheimer’s disease. But they weren’t sure whether REST somehow protected people from death or was just a sign of further aging.

Since it is not currently possible to measure REST in the brains of living people, the scientists began experiments in roundworms and mice to test whether it plays a role in life span. When researchers increased the activity of a worm version of REST, the worms’ brain activity decreased and they lived longer. The opposite happened when scientists disabled the REST-like gene in “Methuselah” roundworms that have very long life spans; the worms’ neural activity increased - and their lives were dramatically shortened. Mice lacking REST were also more likely to have busier brains, including seizure-like bursts of activity.

“I think this is overactivity, out-of-control excitation - it’s not good for the brain. You want the neurons to be active, when and where you want them to be active, not to be just generally firing off,” said Cynthia Kenyon, vice president of aging research at Calico Labs, who praised the study design but said she thinks the nervous system is just one of the many tissues that have an influence on life span.

It’s not yet clear how these differences in brain activity at the level of cells could translate to differences in cognition or behavior in people. [...]

“I think the implication of our study is that with aging, there is some aberrant or deleterious neural activity that not only makes the brain less efficient, but is harmful to the physiology of the person or the animal, and reduces life span as a result,” Yankner said.


13 posted on 10/17/2019 8:36:55 AM PDT by NobleFree ("law is often but the tyrant's will, and always so when it violates the right of an individual")
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To: Red Badger

How much more winning can I stand? LOL!


14 posted on 10/17/2019 8:38:02 AM PDT by rktman ( #My2ndAmend! ----- Enlisted in the Navy in '67 to protect folks rights to strip my rights. WTH?)
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To: DUMBGRUNT

Somebody should have told Leonardo da Vinci and Michaelangelo about this.


15 posted on 10/17/2019 8:39:46 AM PDT by MarvinStinson (a long time waiting for Sanders to return)
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To: DUMBGRUNT

Laziness is good for you.....


16 posted on 10/17/2019 8:41:08 AM PDT by MNJohnnie (They would have to abandon leftism to achieve sanity. Freeper Olog-hai)
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To: Red Badger

TV will make you stupid, but immortal!.........

TV/Hollywood...

Like a hypnotic jewel for many.
They have seen Lucy stomping grapes many times, but stop everything to see it once more.

Worse their world view becomes a view of TV land.

Having been asked if I played Russian roulette in RVN, by some that should simply understand it is a metaphor for the randomness of violence in war.

I ask if they ever experienced a car wreck? Just a few seconds of time.
Now tell me a movie/TV show that was close to duplicating the event???

Terror is something to be avoided.


17 posted on 10/17/2019 8:42:02 AM PDT by DUMBGRUNT
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To: NobleFree

Call it the Algernon Gene...


18 posted on 10/17/2019 8:42:44 AM PDT by Interesting Times (WinterSoldier.com. SwiftVets.com. ToSetTheRecordStraight.com.)
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To: MNJohnnie

RINOs now have a defense.


19 posted on 10/17/2019 8:43:08 AM PDT by AndyJackson
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To: NobleFree

Well that is good news then. People who throw temper tantrums die sooner. Thinkers do not. That is how I read your excerpt.

Wish Antifa and the Dims wouldn’t be taking their sweet time at it.

Would explain Cummings at 68. Peach Foty Fi can’t be far behind.


20 posted on 10/17/2019 8:45:05 AM PDT by LesbianThespianGymnasticMidget (TRUMP TRAIN !!! Get the hell out of the way if you are not on yet because we don't stop for idiots)
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