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Can you regrow your teeth? Japanese scientists develop world's first tooth regrowth drug
Times of India via MSN ^ | 04/2025

Posted on 07/14/2025 9:35:21 AM PDT by SeekAndFind

Losing a tooth is an important developmental stage in childhood, but it is far less pleasant in adulthood. It needs pricey dental substitutes like dentures or implants, but that could soon change. Toregem Biopharma, a Japanese pharmaceutical business, is about to launch a ground-breaking medication designed to promote tooth growth.

The Japan Times claims that the group responsible for this outstanding accomplishment, which was supported by Kyoto University and headed by Toregem Biopharma, had been working hard on the project for years. A medication that targets the suppression of a protein that inhibits tooth growth is the result of their work.

Dr. Katsu Takahashi, a renowned researcher and the head of the dentistry and oral surgery department at the prestigious Medical Research Institute Kitano Hospital, is at the forefront of this medical advancement. When Dr. Takahashi started doing intensive study at Kyoto University in 2005, he began his relentless quest for the regrowth of teeth, an apparently unattainable ambition.

Their ground-breaking discovery is based on a particular mouse gene called USAG-1, which has a significant impact on how teeth form. The dual function of the gene, which may either stimulate or inhibit dental growth, was discovered by the researchers. The crucial concept that surfaced was the development of a "neutralizing antibody medicine" intended to successfully prevent the negative consequences of the USAG-1 gene, thereby opening the door for tooth regrowth.

The scientific community was shocked by the hopeful results of the first trials on mice, which showed that the new medication caused the creation of new teeth. But the researchers wasn't satisfied with their success; they wanted to confirm their findings on ferrets, whose tooth patterns closely resembled those of humans. The experimental medication caused amazing tooth regeneration in the ferrets. It was a turning point in their quest...

(Excerpt) Read more at msn.com ...


TOPICS: Health/Medicine; Science; Society
KEYWORDS: regrowth; teeth; toregenbiopharma
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To: econjack

“The only downside is that the tooth grows out of the end of your nose...”

or a dozen of more new teeth start to grow out in every which direction ...


21 posted on 07/14/2025 9:54:19 AM PDT by catnipman ((A Vote For The Lesser Of Two Evils Still Counts As A Vote For Evil))
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To: SeekAndFind

most organic functions and growth are controlled or influenced by several genes, not just one all by itself.
for instance, information is required to stimulate growth and then again to halt the growth after it has reached the desired amount, degree.

https://www.ebay.com/itm/313007191275

smiles smiles


22 posted on 07/14/2025 9:56:07 AM PDT by faithhopecharity ("Politicians aren't born, they're excreted." Marcus Tullius Cicero (106 to 43 BCE))
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To: SeekAndFind; gundog; SaveFerris

I called the company in Japan and asked for myself. A guy came on in broken English and said “You grow teeth, look like Steve Buscemi!”


23 posted on 07/14/2025 9:59:44 AM PDT by Larry Lucido
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To: SeekAndFind

My dentist keyed me into this research after I lost two back molars to popcorn kernels. Said I should wait on a partial plate since this research is reaching maturation and I’m a prime candidate since I still have a baby tooth in place at age 64 and my wisdom teeth have just started coming in. For decades they assumed I had no wisdom teeth because they never showed on x-rays. A few years ago the two upper teeth appeared pretty much out of nowhere and are slowly dropping down into position.


24 posted on 07/14/2025 10:05:34 AM PDT by Valpal1 (Not even the police are safe from the police!!!)
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To: SeekAndFind

Hope for hockey players!


25 posted on 07/14/2025 10:10:03 AM PDT by married21 (As for me and my house, we will serve the Lord.)
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To: married21

And meth heads


26 posted on 07/14/2025 10:13:11 AM PDT by shotgun
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To: SeekAndFind
1943 WW2 USA AMERICA JAPAN PACIFIC WAR
TOKIO JOE TOJO GENERAL PROPAGANDA POSTER


27 posted on 07/14/2025 10:13:42 AM PDT by Buffalo Bob
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To: shotgun

Yes, actually. But my other thought was military. I wonder if there is a need for wounded soldiers with facial injuries to regrow their teeth.


28 posted on 07/14/2025 10:17:58 AM PDT by married21 (As for me and my house, we will serve the Lord.)
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To: Buffalo Bob

They tested it out on Jimmy too, and it worked like gangbusters.


     

29 posted on 07/14/2025 10:19:08 AM PDT by Songcraft
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To: SeekAndFind

New!


30 posted on 07/14/2025 10:19:22 AM PDT by Honorary Serb (Kosovo is Serbia! Free Srpska! Abolish ICTY!)
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To: simpson96

The side effects in some should be...interesting.“

I was thinking the same thing.


31 posted on 07/14/2025 10:24:47 AM PDT by iamgalt ( )
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To: Jamestown1630

Once you hear the side effects of most drugs, I’m surprised anyone takes any drug!


32 posted on 07/14/2025 10:33:22 AM PDT by econjack
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To: SeekAndFind

I saw an article on this a while back. This process will only work in certain conditions. It won’t just work on anyone. Age may of been a factor but I can’t remember what it was. I just know that it would not have worked on the majority of us.


33 posted on 07/14/2025 10:42:18 AM PDT by Revel
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To: Jamestown1630

The most stupid pharma TV ad “side effects” announcements say “if you are allergic” to this drug - as if anyone whose never tried it knows whether or not they are allergic to it. So stupid, as the pharma lawyers insist on CYA to the nth stupid degree.


34 posted on 07/14/2025 10:57:54 AM PDT by Wuli (uire)
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To: SeekAndFind

If only the new teeth had been formed in the mice’s mouth ...


35 posted on 07/14/2025 11:07:59 AM PDT by PIF (They came for me and mine ... now its your turn)
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To: Wuli

Yes, that puzzled me too. Maybe they mean people who have had side effects but are thinking of trying thr drug again...


36 posted on 07/14/2025 11:15:18 AM PDT by Jamestown1630 ("A Republic, if you can keep it.")
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To: SeekAndFind

That would be amazing....had my first tooth extracted since I was a teenager just a couple weeks ago. Boy, did that suck. Now when that heals, I have to have a post screwed into my jaw. 6 months of healing after that and I can have a crown mounted on that post and be back to where I was before...a lot of pain and several thousand dollars later.


37 posted on 07/14/2025 11:17:35 AM PDT by FLT-bird
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To: FLT-bird

I work with a lady who got full dental implants top & bottom. She had infections and sued the oral surgeon. She told me she could have bought a Cadillac with what she spent as she had the posts installed & removed several times. She was happy during COVID as she could wear a mask. Talked to her the other day and now she’s battling Stage 4 cancer.

I had one of my front biting teeth replaced a couple years ago and that was $5k.


38 posted on 07/14/2025 11:26:54 AM PDT by Mean Daddy
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To: SeekAndFind

Where can I get some?


39 posted on 07/14/2025 11:30:00 AM PDT by Bonemaker (invictus maneo)
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To: Dead Corpse

..”Rabbit” in Japanese.”

Interesting language. Only Japanese word I know is saki.


40 posted on 07/14/2025 11:51:22 AM PDT by Veto! (Trump Is Superman)
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