Posted on 05/04/2025 4:36:40 PM PDT by ChicagoConservative27
Scientists may have identified a way to naturally regulate blood sugar levels and sugar cravings in a similar fashion to drugs like Ozempic.
In mice and humans, the key to unlocking this natural process was found to be a gut microbe and its metabolites – the compounds it produces during digestion.
By increasing the abundance of this one gut microbe in diabetic mice, researchers led by a team at Jiangnan University in China showed they can "orchestrate the secretion of glucagon-like peptide-1".
Glucagon-like peptide-1 (GLP-1) is a hormone that is naturally produced by the body and which helps regulate blood sugar levels and feelings of fullness. GLP-1's release is stimulated by certain foods and gut microbes, and its mechanism of action is mimicked by drugs like semaglutide (the ingredient behind Ozempic).
(Excerpt) Read more at sciencealert.com ...
If you want to lose weight, regulate the carbohydrates. Keep your food natural and only cut back on carbohydrates. You’ll lose weight without using drugs.
I copied “B. vulgatus” from the article. We might have to fire up the Google machine for more details!
I do daily fasting; always a moderate breakfast but I skip lunch, then a respectable dinner. An apple (pink lady variety) and a glass of oj before bed. Blood sugar is way down and I’ve lost 30 pounds in the past 2 1/2 months.
My last meal is about 6 am and I’m happy at 120, lost almost 20 in the last 4 months on a little over 1000 cal/day (blueberries included!) in 2-3 hour window. Whatever eating window fits your schedule.
My last meal is about 6 am and I’m happy at 120, lost almost 20 in the last 4 months on a little over 1000 cal/day (blueberries included!) in 2-3 hour window. Whatever eating window fits your schedule.
My hero.
The most consistent thing I see in overweight persons is that they eat TOO FAST.
When they are ‘full’ it takes too long for their brain to reflect that & to tell the body to stop.
When they use smaller portions-—they eat so fast that they still are “HUNGRY”.
The most consistent thing I see in overweight persons is that they eat TOO FAST.
When they are ‘full’ it takes too long for their brain to reflect that & to tell the body to stop.
When they use smaller portions-—they eat so fast that they still are “HUNGRY”.
I’m diabetic...
My A1C was between 5.8 and 6.2 for years, yet I could not lose weight. Went to a dietician.
She gave me a book and talked about what I could and could not eat.
She also got me on a cam.
I use dexcom7.
Best thing that happened to me.
For the first few days, I was getting alarms at night.
Bells were ringing.
Bongs were bonging.
Lights were flashing.
Turns out my blood sugar crashed at night, resulting in my A1C being so good.
For those that don’t know, diabetes means you can’t regulate your blood sugar.
High blood sugar will kill you eventually.
Low blood sugar will kill you right now, as in you don’t survive the ambulance ride to the hospital.
Diabetics have to eat. This is what makes losing weight so hard for Diabetics.
The company gives me real time blood sugar readings. I can see what different foods do to me. And how much I need to keep my blood sugar in range.
I recommend cgm and consult with a dietician for all diabetics.
Thanks
Darn autocorrect..
cgm keeps getting changed into different words.
CGM is a continuous glucose monitor
What comes out the backside?
It’s called ‘stop stuffing your face with food’.
While promising, B. vulgatus doesn’t fully replicate Ozempic’s effects: Mechanism Difference: Ozempic directly mimics GLP-1 and binds to its receptors, providing consistent, targeted effects. B. vulgatus indirectly boosts GLP-1 through microbial metabolites, which may be less potent or variable.How do you like that? Eat prebiotic fibers; avoid processed foods; avoid excess sugar; and consider fermented foods.Human Evidence is Limited: Most studies are in mice. It’s unclear if B. vulgatus supplementation would have the same effects in humans, as gut microbiomes vary widely.
Complexity of Action: B. vulgatus influences metabolism through multiple pathways (e.g., short-chain fatty acids (SCFA), bile acid metabolism), not just GLP-1, making its effects broader but less specific than Ozempic.
Potential Risks: High levels of B. vulgatus have been linked to conditions like ulcerative colitis in some contexts, indicating strain-specific or context-dependent effects.
Practical Implications
To support B. vulgatus naturally, you can:
Eat prebiotic fibers: Foods like oats, bananas, garlic, leeks, mushrooms, berries, and legumes feed B. vulgatus.Avoid processed foods and excess sugar: These disrupt gut microbiota balance.
Consider fermented foods: Kraut, kimchi, or yogurt may support a healthy microbiome, though their direct impact on B. vulgatus is less clear.
However, there’s no evidence yet that dietary changes alone can replicate Ozempic’s clinical effects. Supplements claiming to boost B. vulgatus or GLP-1 (e.g., prebiotic blends like Supergut) lack robust human trials to match pharmaceutical outcomes.
Critical Perspective
The "natural Ozempic" label is partly clickbait. While B. vulgatus shows promise, it’s not a direct substitute for Ozempic’s potency or specificity. Pharmaceutical GLP-1 agonists underwent rigorous testing, whereas microbiome-based therapies are in early stages. Overhyping B. vulgatus risks misleading people, especially since Ozempic’s shortages have already impacted diabetic patients. Claims about natural alternatives should be scrutinized, as they may oversimplify complex metabolic processes.
Two words.
Intermittent Fasting.
I’ve heard there are studies of diabetics on IF diets for improved glucose control and insulin sensitivity but it isn’t a mainstream treatment,
If you’re working out but not losing weight that’s not necessarily a bad thing.
Muscle tissue weighs more than fat tissue, so as you burn some fat and put on some muscle, you will see the results but you might not lose weight.
I am becoming more carnivore each week. Today I picked up 5 small ribeye steaks to have for dinner each night this week (steaks only, nothing else, including no steak sauce). And I picked up 5 Italian sausage links to have for breakfast each morning. Today I did buy a bag of oranges to have as a nightly "treat", mainly to avoid rickets and increase the fiber a little
When I do go out mid-day on Fridays I always bring half the meal home to stretch over two meals. Also, when dining out, I go to a good restaurant that serves quality food, and always get a salad, just to have some vegetable intake.
I've recently converted my dungeon-like basement into what I call a "boxing gym" (vintage leather boxing gloves should arrive tomorrow to hang on the wall). I've also installed a DLP movie projector down there, and often watch "Rocky" movies while working out after work each day. I've got a few sets of dumbbells, a treadmill and a stationary bike.
Progress is coming slow, but I have found that my trips downstairs to the basement after work each day have become the most enjoyable part of my day.
I do miss chocolate.
Duct tape over the mouth.
As they say…you cannot outrun a bad diet.
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