Native Americans Inherited Lip Shape Gene from Denisovans

Sci News ^ | February 8, 2021 | News Staff

[SunkenCiv]

In a genome-wide association study of 6,169 Latin American individuals, an international team of scientists identified 32 gene regions (loci) that influenced facial features such as nose, lip, jaw, and brow shape, nine of which were entirely new discoveries while the others validated genes with prior limited evidence; one of these genes appears to have been inherited from Denisovans, an extinct sister group of Neanderthals.

Dr. Kaustubh Adhikari, a scientist at University College London and the Open University, and colleagues... compared genetic information from the participants with characteristics of their face shape, quantified with 59 measurements (distances, angles and ratios between set points) from photos of their faces in profile.

They detected significant association of 32 traits with at least 1 (and up to 6) of 32 different genomic regions.

They also found that TBX15, a gene that contributes to lip thickness, was linked with genetic data found in Denisovans, providing a clue to the gene's origin.

[SunkenCiv]

Abstract: It has recently been shown that ancestors of New Guineans and Bougainville Islanders have inherited a proportion of their ancestry from Denisovans, an archaic hominin group from Siberia. However, only a sparse sampling of populations from Southeast Asia and Oceania were analyzed. Here, we quantify Denisova admixture in 33 additional populations from Asia and Oceania. Aboriginal Australians, Near Oceanians, Polynesians, Fijians, east Indonesians, and Mamanwa (a "Negrito" group from the Philippines) have all inherited genetic material from Denisovans, but mainland East Asians, western Indonesians, Jehai (a Negrito group from Malaysia), and Onge (a Negrito group from the Andaman Islands) have not. These results indicate that Denisova gene flow occurred into the common ancestors of New Guineans, Australians, and Mamanwa but not into the ancestors of the Jehai and Onge and suggest that relatives of present-day East Asians were not in Southeast Asia when the Denisova gene flow occurred. Our finding that descendants of the earliest inhabitants of Southeast Asia do not all harbor Denisova admixture is inconsistent with a history in which the Denisova interbreeding occurred in mainland Asia and then spread over Southeast Asia, leading to all its earliest modern human inhabitants. Instead, the data can be most parsimoniously explained if the Denisova gene flow occurred in Southeast Asia itself. Thus, archaic Denisovans must have lived over an extraordinarily broad geographic and ecological range, from Siberia to tropical Asia.

Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania | David Reich et al | Am J Hum Genet | Oct 7 2011

[SunkenCiv]

The rest of the Denisovan keywords, sorted:

• Humans Had Sex With At Least Three Different Denisovan Populations [11/22/2024]
• Multi-layered site in Tajikistan's Zeravshan Valley uncovered, offering new insights into human expansion [11/13/2024]
• Denisovan Bone Discovered on Tibetan Plateau [07/14/2024]
• Scientists link elusive human group to 150,000-year-old Chinese 'dragon man' [04/08/2024]
• Are You a Morning Person? You Might Want to Thank Your Neanderthal Genes [12/14/2023]
• Humans having sex with a now-extinct species 60,000 years ago could be why you suffer from mental health issues, study claims [11/03/2023]
• New path for early human migrations through a once-lush Arabia contradicts a single 'out of Africa' origin [10/09/2023]
• Remains found in China may belong to third human lineage [08/11/2023]
• Mysterious ancient humans may have given people of Papua New Guinea an immune advantage [12/16/2022]
• Researchers chart advances in ancient DNA technology [07/26/2022]
• Molecular archaeology: What ancient genes tell us about who we are [06/06/2022]
• Tooth of an Ancient Girl Fills Gap in Human Family Tree [05/18/2022]
• Ancient Tooth Once Belonged to The Mysterious Denisovans, Scientists Think [05/17/2022]
• Artificial Intelligence Has Found an Unknown 'Ghost' Ancestor in The Human Genome [11/04/2021]
• One Living People Today Show More Traces of The Mysterious Denisovans Than Any Others [08/23/2021]
• Neandertal and Denisovan blood groups deciphered [08/08/2021]
• Just 7% Of Our DNA Is Unique To Modern Humans, Study Shows [07/17/2021]
• Giant Skulls Discovered: They Refuse to Believe the Truth Even When It Is Right in Front of Their Eyes [06/29/2021]
• New Evidence in Search for the Mysterious Denisovans [04/05/2021]
• Scientists Sequence Y Chromosome DNA of Denisovans and Neanderthals [09/27/2020]
• DNA from Denisovans can be found in humans today: DNA from an unknown ancient ancestor of humans that once bred with Denisovans still exists among people today, study reveals [08/07/2020]
• John Hawks - Who were the ancestors of the Neanderthals? [08/02/2020]
• Researchers Sequence Genome of Neanderthal Woman from Chagyrskaya Cave [06/21/2020]
• Humans and Neanderthals: less different than polar and brown bears [06/12/2020]
• Neandertals had older mothers and younger fathers [04/25/2020]
• A study refutes the similarities between the teeth of Denisovans and modern Asians [01/01/2020]
• Southeast Asia was crowded with archaic human groups long before we turned up [07/28/2019]
• Denisovans, A Mysterious Form Of Ancient Humans, Are Traced to Tibet [05/01/2019]
• The first known fossil of a Denisovan skull has been found in a Siberian cave [04/08/2019]
• Extinct human species lived together in Siberian cave, new research shows [02/16/2019]
• 50,000 year old tiara made of woolly mammoth ivory found in world famous Denisova Cave [01/20/2019]
• 'Denisova 11' Had Neanderthal Mother and Denisovan Father [08/27/2018]
• This ancient bone belonged to a child of two extinct human species [Denisovan, Neandertal] [08/23/2018]
• Cave girl was half Neanderthal, half Denisovan [08/22/2018]
• No evidence of 'hobbit' ancestry in genomes of Flores Island pygmies [08/06/2018]
• Homo sapiens developed a new ecological niche that separated it from other hominins [07/30/2018]
• A New Batch of Neanderthal Genome Provides Insights Into Their Complex History [03/26/2018]
• Modern humans interbred with Denisovans twice in history [03/16/2018]
• No Volcanic Winter In East Africa From Ancient Toba (Super-Volcano) Eruption [02/13/2018]
• Is this stunning bracelet made by Paleolithic man for his favourite woman really 70,000 years old? [08/04/2017]
• New DNA From A Neanderthal Bone Reveals Evidence Of A Lost Tribe Of Humans [07/05/2017]
• Neanderthals In California? Maybe So, Provocative Study Says (Denisovians?) [04/27/2017]
• New DNA Study Shows Humans Bred With Unknown Species [01/31/2017]
• Neanderthal Bone Fragment Identified in Denisova Cave [04/02/2016]
• Site in Germany yields human presence over 1 million years ago [03/25/2016]
• A golden age of ancient DNA science begins [03/25/2016]
• 400,000-year-old fossils from Spain provide earliest genetic evidence of Neandertals [03/20/2016]
• Ancient Denisovan DNA excavated in modern Pacific Islanders [03/20/2016]
• Neanderthals boosted our immune system [01/07/2016]
• Latest study suggests early human dispersal into Spain through Strait of Gibraltar [01/02/2016]
• Mysterious 14,000-year-old leg bone may belong to archaic human species [12/20/2015]
• Ancient human ancestor may have persisted through Ice Age [12/17/2015]
• Thigh bone points to unexpectedly long survival of ancient human ancestors [12/17/2015]
• Prehistoric tooth reveals surprising details about long-lost human 'cousins' [11/18/2015]
• DNA from Neandertal relative may shake up human family tree [09/13/2015]
• Stone bracelet is oldest ever found in the world [Denisovan, 40K ago] [05/09/2015]
• Fossil Found In Asia Could Be A New Species Of Human [01/28/2015]
• The Case of the Missing Ancestor: DNA from Russia adds a mysterious new member to the human family [07/04/2014]
• Tibetans get high-altitude edge from extinct Denisovans' genes [07/03/2014]
• Baffling 400,000-Year-Old Clue to Human Origins [12/05/2013]
• Ancient Humans Had Sex With A Mystery Species (Not Neanderthals Or Denisovans) [12/05/2013]
• At 400,000 Years, Oldest Human DNA Yet Found Raises New Mysteries [12/04/2013]
• 'Asian Neanderthals' may have occupied Australia [10/22/2013]
• Ancient Humans Crossed Ocean Barrier? [10/19/2013]
• Modern Humans in India Earlier Than Previously Thought? [09/15/2013]
• Ancient Siberians may have rarely hunted mammoths [06/15/2013]
• Archaeogenetic research refutes earlier findings [06/13/2013]
• Modern Y-Chromosome Variation Surpasses Archaic Humans (article) [05/07/2013]
• Toba super-volcano catastrophe idea 'dismissed' [05/02/2013]
• Researchers Publish Improved Neanderthal Genome [03/19/2013]
• Ancient Mariners: Did Neanderthals Sail to Mediterranean? [11/24/2012]
• Anthropologist suggests Mediterranean islands inhabited much earlier than thought [11/16/2012]
• DNA Unveils Enigmatic Denisovans [09/29/2012]
• How our DNA differs from that of Denisovans, our extinct cousins [09/01/2012]
• Mysterious Chinese Fossils May Be New Human Species [03/14/2012]
• Neanderthals were ancient mariners [03/02/2012]
• Modern Humans Interbred with Archaic Humans in East Asia, Study Says [11/08/2011]
• Many roads lead to Asia (Denisovans, migrations, etc.) [09/26/2011]
• Neanderthal sex boosted immunity in modern humans [08/26/2011]
• Stone Age toe could redraw human family tree [08/12/2011]
• Mating with Neanderthals Good for Human Health [06/17/2011]
• Cretan tools point to 130,000-year-old sea travel [01/03/2011]
• Scientists say new human relative roamed widely in Asia [12/25/2010]
• Genome of extinct Siberian cave-dweller linked to modern-day humans [12/23/2010]
• Ancient humans, dubbed 'Denisovans', interbred with us [12/22/2010]
• DNA says new human relative roamed widely in Asia [12/22/2010]
• Is the Mysterious Siberian "X-Woman" a New Hominid Species? [03/25/2010]
• Gene research reveals fourth human species [03/24/2010]
• Possible new human ancestor found in SiberiaPossible new human ancestor found in Siberia [03/24/2010]
• DNA identifies new ancient human dubbed 'X-woman' [03/24/2010]
• New ancestor? Scientists ponder DNA from Siberia [03/24/2010]
• 'Pompeii-Like' Excavations Tell Us More About Toba Super-Eruption [03/04/2010]
• On Crete, New Evidence of Very Ancient Mariners [02/17/2010]
• Ancient hominids may have been seafarers [01/14/2010]
• Super-Eruption: No Problem (Toba) [07/06/2007]

[SunkenCiv]

[Uncle Miltie]

Ttiuwp

[Uncle Miltie]

[Flaming Conservative]

How have I survived this long without knowing this?

[Maskot]

Right? This where our tax money goes? Completely useless studies?

[Pontiac]

Looks like a girl I knew in high school.

[Pontiac]

This where our tax money goes?

You lucked out on this bit of useless knowledge.

It was produced by the University College of London (England).

But, I am sure that with little effort you can find an even more useless example of scientific research that US tax payers funded.

As much as I enjoy reading this sort of thing I believe that taxpayer funded research should be restricted to the sort that DARPA performs and even that should be strictly scrutinized.

Government funding inevitably corrupts the science it funds.

Climate Change is a prime example of this fact.

[Vermont Lt]

Those little Denisovan chicks were cute. Not bossy like the Neanderthals.

[Steely Tom]

Does this explain Heather Locklear ?

[econjack]

You know...I probably could have survived without knowing this.

[antidemoncrat]

And all this time I thought they inherited it from a bathroom plunger.

[PIF]

Those little Denisovan chicks were cute. Not bossy like the Neanderthals.

—
Cute, but taller and stronger by half than the average Neanderthal chick.

[oldplayer]

Interesting, Sunken Civ. Not so much about what it says about Indians, but what it says about how Neanderthal and Denisovans’ traits in general have entered the homo sapiens gene pool.

[kelly4c]

What an awesome list! Definite bookmark :)

[SunkenCiv]

That must be the worst of the www acronyms. :^)

[SunkenCiv]

https://freerepublic.com/focus/chat/4289209/posts?page=12#12

[SunkenCiv]

https://freerepublic.com/focus/chat/4289209/posts?page=6#6

[SunkenCiv]

My pleasure.