Posted on 11/13/2024 2:53:19 PM PST by ConservativeMind
A study led by Prof. Bernard Lerer shows promising results for using psilocybin, a psychedelic compound, as a potential treatment for obsessive-compulsive disorder (OCD) and Tourette's syndrome.
The research provides significant insights into the benefits of psilocybin for managing symptoms similar to those experienced by people with OCD and Tourette's syndrome.
The study included 50 genetically modified mice that displayed excessive grooming and anxiety, similar to human OCD behaviors and head-body twitches similar to tics suffered by patients with Tourette's syndrome.
These mice were randomly given either a single injection of psilocybin, a psychedelic mushroom extract, or a placebo. Raters, unaware of which treatment each mouse received, evaluated the effects at several points over a three-week period.
Mice treated with psilocybin showed a 14.60% decrease in excessive grooming, while those receiving the mushroom extract saw a 19.20% reduction, compared to a significant increase of 118.71 in grooming in the placebo group. The study also observed reductions in other symptoms like tic-like movements and anxiety, with the mushroom extract showing greater benefit in its effect on anxiety. Additionally, the positive effects from a single treatment lasted up to seven weeks in some mice.-0
"Understanding that over 40% of OCD patients don't find relief with current treatments, our findings are crucial as they suggest a new way to help these individuals," Prof. Lerer noted.
"We look forward to advancing to human trials and further exploring how these treatments can provide long-term benefits. The effects observed on tic-like head and body twitches raise the previously unreported possibility that psilocybin may be effective in patients with Tourette's syndrome."
This research highlights the potential of psilocybin and similar substances in treating psychiatric conditions and supports ongoing efforts to discover new, effective mental health therapies.
(Excerpt) Read more at medicalxpress.com ...
DAMN I love those mushrooms!
No. Also Ketamine. No.
And SO much material has yet to avalanche in regarding just how massively harmful Weed is.
Medications shouldn’t be re-purposed abused hallucinogenics.
Instead of promoting hallucinogenics, it’s more than likely that lowering the dose and managing shorter term, more responsible regimens of existing antidepressants and such is the right route.
I never eat anything that looks like a cat dropping.
Funny how everyone’s favorite recreational drugs become the newest and most effective medicine. Of all the botanicals in nature, it just so happens that the only ones that seem to work are the ones that get you high. What a coincidence!
Exactly 🙄
“Psilocybin shows promise as new treatment for OCD and Tourette’s syndrome, finds study”
And many folks say Psilly is good to take on Sunny Saturdays in the Park.
To each his/hers/yet to decides own.
I remember when Ecstasy first came out.
Time Magazine thought it was a wonder drug.
When the men on the chessboard
Get up and tell you where to go
And you’ve just had some kind of mushroom
And your mind is moving low
Go ask Alice
I think she’ll know
Studies like this have usually involved micro dosing, not ‘recreational’ doses. This article doesn’t say.
I took that about 25 years ago and it was very bizarre, it turned me into a liberal for a night, suddenly I loved everybody. It boosted my empathy to this ridiculous level “Oh so what if Ted Bundy mass murdered women, show compassion for him, he just wants love”
**I remember when Ecstasy first came out. Time Magazine thought it was a wonder drug.**
Should be legal. At least in old folks homes.
Would be nice if it was true
I wonder if people need to take regularly or a few doses. One thing I loathe is experiments on animals. In President Trump’s first term he put a stop to using animals in experiments. Computers can do the job now, and better, without cruelty.
People who had lobotomies sat still. So?
As a child of the sixties who had a damn good time I am highly skeptical of this article. Don’t think genetically modified mice qualify for any serious conclusions.
This is some heavy shit. And I know some people, or I should say knew, since they’re not here anymore, who took some heavy duty hits from psychedelics.
Also, considering the whorrish state of medical research in this country, I think severe skepticism is warranted
I’m also a 60’s old fart who dabbled in just about anything passed my way. But I got tired of living in a cloud and what was all new soon grew old. “Shrooms” are not something to fool around with. I cannot imagine someone with Tourette’s syndrome seeing things that may or may not be there and reality has taken a wrong turn somewhere. I can only imagine it would make their condition worse.
Experimented with mushrooms once or twice. First time was in the company of a classmate who went on to win several Olympic gold medals.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.