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Very high levels of 'good cholesterol' may be associated with dementia risk, study shows (HDL > 80 mg/dL = 27 - 42% increased risk)
Medical Xpress / Monash University / The Lancet Regional Health—Western Pacific ^ | Nov. 30, 2023 | Dr. Monira Hussain et al

Posted on 12/04/2023 9:29:27 AM PST by ConservativeMind

Abnormally high levels of HDL-C, colloquially known as "good cholesterol," are associated with an increased risk of dementia in older adults, a study has found.

Researchers said very high levels of HDL-C linked to dementia risk in this study were uncommon and not diet related, but more likely to reflect a metabolic disorder.

The findings may help doctors to recognize a group of older patients potentially at risk of dementia.

Over an average 6.3 years, participants with very high HDL-C (>80 mg/dL or >2.07 mmol/L) at study entry were observed to have a 27% higher risk of dementia compared to participants with optimal HDL-C levels, while those aged 75 years and older also showed a 42% increased risk compared to those with optimal levels.

Very high HDL-C levels were categorized as 80 mg/dL (>2.07 mmol/L) or above. The optimal level of HDL-C of 40 to 60 mg/dL (1.03–1.55 mmol/L) for men and 50 to 60 mg/dL (1.55–2.07 mmol/L) for women was generally beneficial for heart health.

Among 18,668 participants included in this analysis, 2,709 had very high HDL-C at study entry, with 38 incidents of dementia in those aged less than 75 years with very high levels, and 101 in those aged 75 and more with very high levels.

First author Dr. Monira Hussain said that further research was needed to explain why a very high HDL cholesterol level appeared to affect the risk of dementia.

Dr. Hussain said, "While we know HDL cholesterol is important for cardiovascular health, this study suggests that we need further research to understand the role of very high HDL cholesterol in the context of brain health."

"It may be beneficial to consider very high HDL cholesterol levels in prediction algorithms for dementia risk."

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: cholesterol; dementia; hdlc; hdlcholesterol; wereallgonnadiesoon
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There appears to be a likely limit to the good cholesterol, HDL.
1 posted on 12/04/2023 9:29:27 AM PST by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

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2 posted on 12/04/2023 9:29:58 AM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

“....”good cholesterol,” are associated with an increased risk of dementia ....”

Then it’s not “good” cholesterol”.


3 posted on 12/04/2023 9:30:53 AM PST by mikelets456
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To: ConservativeMind

🤦‍♂️...........................


4 posted on 12/04/2023 9:31:53 AM PST by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: ConservativeMind

High levels of HDL may bless you with a life long enough to develop dementia. Low levels may lead to early death and no dementia.


5 posted on 12/04/2023 9:38:31 AM PST by muir_redwoods (Freedom isn't free, liberty isn't liberal and you'll never find anything Right on the Left)
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To: muir_redwoods

I’ve read it has a lot to do with Sugar consumption too. Who knows.


6 posted on 12/04/2023 9:44:48 AM PST by CommieCutter
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To: ConservativeMind

I’m at 44, so safe from dementia! Also helps I’m not a Democrat.


7 posted on 12/04/2023 9:44:52 AM PST by AlaskaErik (There are three kinds of rats: Rats, Damned Rats, and DemocRats.)
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To: ConservativeMind

Gotta take the good with the bad.


8 posted on 12/04/2023 9:44:54 AM PST by Signalman
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To: ConservativeMind

I sense a new fizzer drug coming out.


9 posted on 12/04/2023 9:48:21 AM PST by GMThrust
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To: AlaskaErik

Wow, a youngster on FR!


10 posted on 12/04/2023 9:54:24 AM PST by Rennes Templar (Come back, President Trump.)
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To: ConservativeMind

Yeah that’s the first time I’ve seen an upper limit for HDL cholesteral.

I’m still trying to figure out what are the optimal ranges for the LDL considering that now there are two types of LDL. Good LDL lb bad LDL-hd


11 posted on 12/04/2023 9:55:16 AM PST by ckilmer (ui)
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To: ConservativeMind

.


12 posted on 12/04/2023 9:57:08 AM PST by sauropod (The obedient always think of themselves as virtuous rather than cowardly.)
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To: ConservativeMind

No matter what you do, you are wrong.


13 posted on 12/04/2023 10:01:09 AM PST by Seruzawa ("The Political left is the Garden of Eden of incompetence" - Marx the Smarter (Groucho))
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To: ConservativeMind

Had mine checked last week and it’s 66. I’m safe.


14 posted on 12/04/2023 10:03:28 AM PST by Melinda in TN
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To: mikelets456
Then it’s not “good” cholesterol”.

It is a very good cholesterol, it was turning its fatty acids around and was about to cut an albumin.
15 posted on 12/04/2023 10:09:01 AM PST by posterchild
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To: ConservativeMind

I wouldn’t be surprised if they find out statins cause dementia.

The number of people I know suffering from dementia at a young age is unusual.


16 posted on 12/04/2023 10:21:47 AM PST by MeanWestTexan (Sometimes There Is No Lesser Of Two Evils)
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To: Melinda in TN

My HDL has a comma in it.


17 posted on 12/04/2023 10:22:50 AM PST by Laslo Fripp (Semper Fidelis)
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To: ConservativeMind

My good cholesterol is never high, it’s always low.


18 posted on 12/04/2023 10:31:32 AM PST by BigFreakinToad (Remember the Biden Kitchen Fire of 2004)
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To: ConservativeMind

There appears to be a need to sell more statins.


19 posted on 12/04/2023 10:48:42 AM PST by zek157
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To: Melinda in TN

I just had my highest HDL in years. It was 35. My all time high was 38.


20 posted on 12/04/2023 10:50:05 AM PST by Dutch Boy (The only thing worse than having something taken from you is to have it returned broken. )
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