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Powerful new obesity drug poised to upend weight loss care
AP ^ | April 27, 2023 GMT | By JONEL ALECCIA

Posted on 04/28/2023 5:25:16 AM PDT by Red Badger

As a growing number of overweight Americans clamor for Ozempic and Wegovy — drugs touted by celebrities and on TikTok to pare pounds — an even more powerful obesity medicine is poised to upend treatment.

Tirzepatide, an Eli Lilly and Co. drug approved to treat type 2 diabetes under the brand name Mounjaro, helped people with the disease who were overweight or had obesity lose up to 16% of their body weight, or more than 34 pounds, over nearly 17 months, the company said on Thursday.

The late-stage study of the drug for weight loss adds to earlier evidence that similar participants without diabetes lost up to 22% of their body weight over that period with weekly injections of the drug. For a typical patient on the highest dose, that meant shedding more than 50 pounds.

Having diabetes makes it notoriously difficult to lose weight, said Dr. Nadia Ahmad, Lilly’s medical director of obesity clinical development, which means the recent results are especially significant. “We have not seen this degree of weight reduction,” she said

Based on the new results, which have not yet been published in full, company officials said they will finalize an application to the U.S. Food and Drug Administration for fast-track approval to sell tirzepatide for chronic weight management. A decision could come later this year. A company spokeswoman would not confirm whether the drug would be marketed for weight loss in the U.S. under a different brand name.

(Excerpt) Read more at 12ft.io ...


TOPICS: Business/Economy; Food; Health/Medicine; Society
KEYWORDS: eatless; obesity; weight
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1 posted on 04/28/2023 5:25:16 AM PDT by Red Badger
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To: Red Badger

How do these work ?


2 posted on 04/28/2023 5:28:07 AM PDT by DouglasKC
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To: DouglasKC

I don’t know about THIS on in particular, but when I was in the hospital back in 2020 for my quad by-pass, I lost nearly 30 pounds in a month just because they gave me insulin injections that I had never had before in my life, because they said my blood sugar was a bit too high.

Also, the food sucked....................


3 posted on 04/28/2023 5:30:24 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: DouglasKC

I’ve been on Ozempic for my Type II diabetes for a couple years now. It didn’t really make a difference with weight loss for me.

Then, after an auto accident which messed up my back, my pain management doctor told me if I lost the weight (I was over 300), I could avoid surgery. I went on Nutrisystem and over the course of 18 months I lost 100 pounds. And no surgery needed.

So Ozempic? Maybe it helped with my Nutrisystem, I can’t say for sure.


4 posted on 04/28/2023 5:33:28 AM PDT by COBOL2Java (Gun laws empower criminals. Guns empower the people.)
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To: Red Badger

Costs a kilobuck a month.

Here’s another approach that’s free:

“Here We Go With PolyPharmacy”

https://market-ticker.org/akcs-www?post=248664


5 posted on 04/28/2023 5:39:42 AM PDT by DuncanWaring (The Lord uses the good ones; the bad ones use the Lord.)
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To: DouglasKC

They actually work by treating insulin resistance and probably by a hormonal component that reduces appetite. These are the first drugs that actually work for weight loss. Obviously adding exercise and watching the diet help But we have seen amazing weight loss in people who have not been able to lose before


6 posted on 04/28/2023 5:45:01 AM PDT by Mom MD ( )
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To: Red Badger

I was diagnosed with type2 the first of the year. I stopped drinking fizzy drinks and stopped eating all the stuff the literature says not to eat. I also started using an under desk elliptical just after Thanksgiving of last year. I don’t know what they’re talking about, I’ve lost over 80lbs since Thanksgiving. I’m only on metformin and my doctor expects me to be “done” with diabetes by the end of the year.

I’m fairly certain it really is down to diet and exercise for most of us. What I’m doing can hardly be called exercise anyhow, I’m just sitting here like I have my entire life, the only difference is my feet are constantly in motion and maybe for 5 minutes every hour I peddle like I’m being chased by leftists.

I’ll go a bit further and suggest it’s all the processed stuff we’re consuming. People need to go back to making their own meals, which would have the added benefit of wrecking the parasitical chain restaurant industry as well.

I realize I sound like an ex-smoker (which hilariously I am) but I never got on a soapbox about smoking but this fatdemic is stupid beyond words.

My doctor wanted to put me on insulin, ozempic and some other insanely expensive drug and I talked him out of it. He looked like he might have been about to cry at the first follow up because I did what he told me to do, apparently hardly anyone does as they’re told which is why doctors go straight for insulin. I’m convinced the overwhelming majority of people who don’t lose the weight and get their blood sugar under control are stuffing pies in their faces in the middle of the night.


7 posted on 04/28/2023 5:48:52 AM PDT by Legatus (May the zot be with you)
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To: Mom MD

9.4 points on my A1C and a pound and a half a week for me for the 9 monthsI havw taken it. 14.8 to 5.4. Down 87 pounds, but that is secondary to me.


8 posted on 04/28/2023 5:52:54 AM PDT by Ingtar
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To: Red Badger

But I would guess, your portion control is not under your control and that might be impacting your weight. Hubby has a several extended hospital stays and after the first few days they are giving him no insulin and he’s not complaining about food but I can see that he’s not filling a dinner plate full to the edge. Portion control is something we talk about a lot. Like the number of cookies in ONE serving, the number of carbs in one cookie, potato chip, or pancake.

Congrats on weight loss, sorry about the food.


9 posted on 04/28/2023 5:54:11 AM PDT by grame (May you know more of the love of God Almighty this day!)
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To: Red Badger

“Also, the food sucked”

that’ll do it ...


10 posted on 04/28/2023 5:54:40 AM PDT by catnipman (In a post-covid world, ALL "science" is now political science: stolen elections have consequences)
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To: Legatus

(Moonpies!).........................


11 posted on 04/28/2023 5:55:17 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: DuncanWaring

Thanks for that, it corresponds with my own experience. It’s funny that spaghetti was mentioned because I tried whole wheat pasta last week and about killed myself. My blood sugar was 311 a couple hours after eating when “normally” it’s around 130ish. Although in the WEIRDEST experiment yet I ate KFC original recipe AND fries and an hour later it was 110. That was why we thought whole wheat pasta might be doable.

It seems for me that almost anything that comes in a box is dangerous.


12 posted on 04/28/2023 6:00:40 AM PDT by Legatus (May the zot be with you)
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To: DouglasKC

How (does this) work?
~~~~~

https://www.youtube.com/watch?v=wZPLJwlhdn4


13 posted on 04/28/2023 6:01:27 AM PDT by nagant
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To: Legatus

Did you ever try the pasta made from Brown Rice ?

I’m pushing my diet toward only stuff with high fiber.


14 posted on 04/28/2023 6:09:39 AM PDT by George from New England
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To: Red Badger
”34 pounds, over nearly 17 months”

Conservatively, you can expect to lose that in 4 months on a low carb diet, assuming 1/3-lb per day after a 2-week start-up period.

The diabetes drug is very interesting, but it is still a drug from big pharma and may have weird and bad side effects they are not disclosing

15 posted on 04/28/2023 6:13:24 AM PDT by UnwashedPeasant (The pandemic we suffer from is not COVID. It is Marxist Democrat Leftism.)
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To: UnwashedPeasant

What it’s like to take the blockbuster drugs Ozempic and Wegovy, from severe side effects to losing 50 pounds...........

https://www.nbcnews.com/health/health-news/ozempic-wegovy-diabetes-weight-loss-side-effects-rcna66493


16 posted on 04/28/2023 6:14:40 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: Ingtar

amazing. CongrTulations on your hard work. You have added years to your life


17 posted on 04/28/2023 6:19:25 AM PDT by Mom MD ( )
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To: grame

One serving......................

18 posted on 04/28/2023 6:19:38 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: Red Badger
Noted in the link you posted:

"Ozempic is not approved for weight loss, but doctors sometimes prescribe it off-label for that purpose."

Gee, I thought that doctors who did such things were threatened with loss of license, finings, imprisonment, being canceled on social media, and being called a terrorist.

19 posted on 04/28/2023 6:21:03 AM PDT by alancarp (George Orwell was an optimist.)
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To: Red Badger

Wonder if it has mRNA in it /s


20 posted on 04/28/2023 6:21:22 AM PDT by goodnesswins ( We pretend to vote and they pretend to count the votes.)
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