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U of M study: Ivermectin not an effective treatment for COVID-19
KSTP.com ^ | 8/17/22 | Ryan Raiche

Posted on 08/18/2022 8:49:39 AM PDT by ButThreeLeftsDo

A long-awaited study at the University of Minnesota has found that the controversial drug ivermectin is not effective at treating COVID-19.

The findings, published Wednesday in the New England Journal of Medicine, add to a growing body of scientific evidence pushing back against the use of the antiparasitic drug that has been promoted by some prominent voices on social media.

The U of M’s study focused on three common drugs: ivermectin, metformin, and fluvoxamine. Researchers determined that none of the drugs proved effective at preventing low oxygen levels, ER visits, hospitalization or death.

The study showed some promise for the diabetes drug metformin, but the data is not definitive.

“We’re just really grateful to be able to share our work broadly and to have been published in a medical journal,” said Dr. Carolyn Bramante, the lead researcher on the study.

The team’s study is now at least the third large-scale study on ivermectin released this year that found the drug is not effective in treating COVID-19.

5 INVESTIGATES started following the issue months ago, soon after fights to get the drug went from the hospital room to the courtroom.

Some patients filed lawsuits against hospitals and doctors that refused to prescribe the controversial drug.

“I’ve done a lot of research on it,” Kathy Huspek told 5 INVESTIGATES back in January for why she filed a lawsuit against St. John’s Hospital in Maplewood shortly after her husband Gerry was admitted to the ICU.

A judge refused to intervene, saying he cannot force a hospital to use a drug that is “not within the standard of care.”

Researchers at the U of M hope the new results help patients understand what actually works in treating COVID-19.

“The virus is changing. And so we need all the tools in the toolbox that we can get as we combat this virus,” Bramante said.


TOPICS: Health/Medicine; Local News; Miscellaneous; Science
KEYWORDS: appleflavored; covid; ilikethehorsepills; itake1aday; itdoesntwork; ivermectin; ivm; minnesota
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To: ButThreeLeftsDo
They gave Ivermectin 3 days after infection and 7 days after symptoms. And no mention of Zinc.

Hit piece for the #IFLS morons.

41 posted on 08/18/2022 9:35:22 AM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: struggle
>effective at preventing low oxygen levels, ER visits, hospitalization or

You really needed to post the whole sentence, because what you provided makes it seem like it was effective regarding the items listed 🙂:

Researchers determined that none of the drugs proved effective at preventing low oxygen levels, ER visits, hospitalization or death.

But I agree, dosage coupled with the early administration, in the confirmation period of infection, are important aspects of the treatment.

Yet another dishonest study executed with the per-designed outcome to fit the conclusion due to misapplication of the process.

42 posted on 08/18/2022 9:36:39 AM PDT by Robert DeLong
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To: semimojo

There you go bringing facts into it again


43 posted on 08/18/2022 9:36:53 AM PDT by Mom MD ( )
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To: suijuris
Forgot to mention. Had an 8th friend. As soon as I found out he had COVID I offered him the Zelenko ivermectin protocol. He declined three times. He ended up in the hospital 2 months. Was on a vent nearly 40 days. Fortunately he survived, but still not totally back. The other seven friends all got over COVID in about 2 days.
44 posted on 08/18/2022 9:39:38 AM PDT by suijuris (Once a man learns to see he finds himself alone in the world with nothing but folly.)
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To: Nifster

“Vaccines are never treatments”

Vaccines are not vaccines.


45 posted on 08/18/2022 9:39:58 AM PDT by alternatives? (The only reason to have an army is to defend your borders.)
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To: ButThreeLeftsDo

Yeh sure. 🙄


46 posted on 08/18/2022 9:40:29 AM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: ButThreeLeftsDo

More big pharma propaganda from a left-wing university. I have the horse paste in my frig and every time I get a sore throat or feel like I’m getting sick, I take a pinky fingernail size glop for 3 days and bingo, it’s gone. Haven’t had the China Virus and don’t want it!


47 posted on 08/18/2022 9:44:42 AM PDT by Lucky2 (#Let's Go Brandon, #FJB)
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To: ButThreeLeftsDo
Researchers at the U of M hope the new results help patients understand what actually works in treating COVID-19.

From my husband's experience, Ivermectin.

For me, budesonide.

But then we are a State family.

48 posted on 08/18/2022 9:44:52 AM PDT by Harmless Teddy Bear (The nation of france was named after a hedgehog... The hedgehog's name was Kevin... Don't ask)
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To: BrexitBen

“Except that it DID work magnificently for me, my family, and a number of friends.”

With a 99% or more survival rate, it would take a trial involving many thousands to collect meaningful data. If you took 500 people, and expect 495-499 to survive doing nothing, then how many would it take to get a statistically meaningful number?

That said, NO SCIENTIFIC STUDY means squat UNTIL you read how the study was constructed. For example, a recent study said eating grapes would add 5 years to your life...but it was done on mice, not humans. And involved freeze-dried extracts, not grapes. AND it was funded by a grape growers association:

https://www.youtube.com/watch?v=iAEV-GH6UGw


49 posted on 08/18/2022 9:45:50 AM PDT by Mr Rogers (We're a nation of feelings, not thoughts.)
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To: ButThreeLeftsDo
The trial was funded by the Parsemus Foundation, Rainwater Charitable Foundation, Fast Grants, and UnitedHealth Group Foundation. The funders had no role in the design or conduct of the trial and were not involved in the collection or analysis of the data, in the writing of the manuscript, or in making the decision to submit the manuscript for publication. The authors assume responsibility for the fidelity of the trial to the protocol and for the accuracy and completeness of the data and analyses.

What we don't know, is if they made funding contingent upon
a) waiting until the people had had covid for 3 days and
b) symptoms within the last 7 days.

Eligibility criteria included an age of 30 to 85 years; a body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) associated with overweight or obesity; proof of SARS-CoV-2 infection within the past 3 days; and an onset of symptoms within 7 days before randomization. Details regarding the inclusion and exclusion criteria and BMI values are provided in the Supplementary Appendix, available at NEJM.org.

50 posted on 08/18/2022 9:48:34 AM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: bray

I know how much ivermectin to use, but not sure on the zinc?


51 posted on 08/18/2022 9:49:26 AM PDT by avenir (Information overload = Pattern recognition)
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To: ButThreeLeftsDo

I guess health officials on several continents will be much surprised...


52 posted on 08/18/2022 9:50:58 AM PDT by grobdriver (The CDC can KMA!)
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To: semimojo
I suppose you would not get paid if you did not spread a bunch of BS on FR everyday.
53 posted on 08/18/2022 9:51:08 AM PDT by Harmless Teddy Bear (The nation of france was named after a hedgehog... The hedgehog's name was Kevin... Don't ask)
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To: ButThreeLeftsDo
Whatever.

They lie like rugs.

54 posted on 08/18/2022 9:51:45 AM PDT by kiryandil (China Joe and Paycheck Hunter - the Chink in America's defenses)
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To: BrexitBen; ButThreeLeftsDo

Here is what they found:

“The adjusted odds ratio for a primary event was 0.84 (95% confidence interval [CI], 0.66 to 1.09; P=0.19) with metformin, 1.05 (95% CI, 0.76 to 1.45; P=0.78) with ivermectin, and 0.94 (95% CI, 0.66 to 1.36; P=0.75) with fluvoxamine. In prespecified secondary analyses, the adjusted odds ratio for emergency department visit, hospitalization, or death was 0.58 (95% CI, 0.35 to 0.94) with metformin, 1.39 (95% CI, 0.72 to 2.69) with ivermectin, and 1.17 (95% CI, 0.57 to 2.40) with fluvoxamine. The adjusted odds ratio for hospitalization or death was 0.47 (95% CI, 0.20 to 1.11) with metformin, 0.73 (95% CI, 0.19 to 2.77) with ivermectin, and 1.11 (95% CI, 0.33 to 3.76) with fluvoxamine.”

https://www.nejm.org/doi/full/10.1056/NEJMoa2201662

Now, what do we know about confidence intervals:

“If the confidence interval crosses 1 (e.g. 95%CI 0.9-1.1) this implies there is no difference between arms of the study.” IOW, when the confidence interval crosses one, you don’t actually know ANYTHING.

So to repeat,, what did they find out about Ivermectin treatment?

“The adjusted odds ratio for hospitalization or death was...0.73 (95% CI, 0.19 to 2.77) with ivermectin”

The interval is 0.19 to 2.77. IOW, THEY DON’T KNOW JACK SHIT!

A proper summary would be, “We didn’t have enough numbers to learn anything from this experiment, so you might as well toss this in the trash!”

Please notice EVERY CONFIDENCE LEVEL crossed one, and crossed it GROSSLY: “0.19 to 2.77”!


55 posted on 08/18/2022 9:56:57 AM PDT by Mr Rogers (We're a nation of feelings, not thoughts.)
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To: ButThreeLeftsDo
The study showed some promise for the diabetes drug metformin, but the data is not definitive.

I was coincidentally put on Metformin a day or so before I came down with Covid. My case was very mild. Mostly just tired for a week, and a lingering cough. Interesting.
56 posted on 08/18/2022 9:57:03 AM PDT by rickomatic
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To: ButThreeLeftsDo

no mention of zinc

i know i was sick as a dog including chest congestion

the FLCCC protocol(ivermectin, zinc, etc.) cleared it up in 48 hours

fortunately i had the ivermectin on hand

was it covid? i dont know but it cleared out my lungs and back to work in 48 hours


57 posted on 08/18/2022 9:58:23 AM PDT by joshua c (where did my tagline go?)
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To: BrexitBen

“Except that it DID work magnificently for me, my family, and a number of friends.”

Me, too.

I bought another five-day regimen last week, and was surprised that the dosage was higher than it was a year ago. The pharmacist said the newer strains need higher doses. The current strain isn’t as dangerous, but may be more contagious.


58 posted on 08/18/2022 10:00:51 AM PDT by MayflowerMadam (Sometimes when you get to where you're supposed to be, it's too soon.)
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To: ButThreeLeftsDo

This study is a complete farce. They never used Zinc with Ivermectin. All the Ivermectin protocols call for Zinc to be used in combination with Ivermectin in order to successfully treat Covid. This idiots have not proven anything except their stupidity or duplicity or both.


59 posted on 08/18/2022 10:02:19 AM PDT by LibFreeUSA
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To: ButThreeLeftsDo

I know one lady that has been on oxygen since I’ve known her 10+ years. Thought she would last a day if she ever caught the virus. When I found out she had actually caught it she said her DR gave her ivermectin and within a couple hours she started feeling better.

She got the virus at the end of the 1st wave too not the weak strain.


60 posted on 08/18/2022 10:06:01 AM PDT by dgbrown
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