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Study explores the effects of eating dark chocolate on the brain
https://medicalxpress.com ^ | Jul 14, 2022 | by Ingrid Fadelli , Medical Xpress

Posted on 07/15/2022 1:17:21 PM PDT by Red Badger

Eating chocolate is typically discouraged by nutritionists, as it is can be high in calories, fat and sugar. Cocoa, however, chocolate's primary ingredient derived from the seed of the cacao plant, has been found to have numerous qualities that could be beneficial for both the body and mind.

Most notably, pure cocoa is highly nutritious and is a powerful source of antioxidants, substances that can prevent or slow down cell damage caused by free radicals. Free radicals are unstable and highly reactive molecules produced by the body when responding to environmental stresses, which are associated with aging and disease. In addition, cocoa has been found to help regulate the blood pressure and prevent cognitive decline.

Despite these potentially beneficial properties, chocolate bars rarely contain cocoa alone, but also sugar, oils, butter, and other ingredients that are unhealthy for the body. The healthiest type of chocolate is thus likely to be dark chocolate comprised of high percentages of cocoa.

Elham Kalantarzedeh, Maryam Radahmadi and Parham Reisi, three researchers at Isfahan University of Medical Science in Iran have recently carried out a study on rats investigating the impact of different dark chocolate dietary patterns on synapses in a specific region of the brain, known as the hippocampal CA1 area. Their findings, published in Nutritional Neuroscience, suggest that dark chocolate consumption could have beneficial effects on the brain of individuals exhibiting chronic isolation stress.

"Although stress causes brain dysfunction, consumption of dark chocolate (DC) has positive effects on brain functions," the researchers wrote in their paper. "The current study investigated the impact of different DC dietary patterns on synaptic potency and plasticity in the hippocampal CA1 area, as well as food intake and body weight in rats under chronic isolation stress."

Essentially, Kalantarzedeh and her colleagues wanted to determine whether eating dark chocolate in different degrees affected the potency and plasticity (i.e., adaptability over time) of synapses (i.e., tiny gaps across which different neurons communicate with each other) in the hippocampal CA1 area.

To do this, they took 35 rats and divided them into five groups of 7, each of which was fed dark chocolate while experiencing chronic isolation stress, with each group following a different dietary pattern. The three dark chocolate dietary patterns they tested were dubbed stress-compulsory, stress-optional and stress-restricted.

"The stressed rats on a compulsory diet only received DC and the ones on an optional diet received unlimited chow and/or DC," the researchers wrote in their paper. "Also, the stressed rats on a restricted diet each received chow freely and only 4 g DC daily. Subsequently, the slope and amplitude of field excitatory postsynaptic potentials (fEPSPs) were assessed based on the Input-Output (I/O) curves and after the long-term potentiation (LTP)."

The researchers also measured the food intake and body weight of the rats they tested on at the beginning and end of their experiment. Interestingly, they found that all the dark chocolate dietary patterns reduced both the rats' food intake and their body weight. The strongest effects, however, were those caused by compulsory and restricted dietary patterns.

"The fEPSP slope and amplitude in the I/O curves and after LTP decreased significantly in the stress group compared to the control group," the researchers wrote in their paper. "Although the slope and amplitude both enhanced non-significantly in the optional DC diet, these parameters changed significantly in both compulsory and restricted DC dietary patterns compared to the stress group. Also, food intake and body weight decreased significantly in all DC groups."

Overall, the experiments carried out by this team of researchers suggest that the systematic consumption of dark chocolate could reverse the adverse effects of chronic isolation stress on the synaptic potency and plasticity of the hippocampal CA1 area. This would in turn have beneficial effects on both memory and learning.

As their study was carried out in rats, however, to be applicable to humans, their findings would need to be validated on a human sample of participants. If their results were confirmed in future studies involving humans, their work would offer evidence of the positive effects of cocoa on the brain and on cognitive abilities.

Explore further

Dark chocolate may do your heart good this Valentine's Day

More information: Elham Kalantarzadeh et al, The impact of different dark chocolate dietary patterns on synaptic potency and plasticity in the hippocampal CA1 area of the rats under chronic isolation stress, Nutritional Neuroscience (2022).

DOI: 10.1080/1028415X.2022.2088946

© 2022 Science X Network


TOPICS: Business/Economy; Food; Health/Medicine; Society
KEYWORDS: chocolate; chocolatehoax2; darkchocolate; food; health
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To: Red Badger
"... their findings would need to be validated on a human sample of participants

Me me me me me me me me me me me me me....

21 posted on 07/15/2022 6:17:11 PM PDT by DannyTN
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To: Scrambler Bob

I wandered if anyone else thought the title was terribly written.

Maybe you put a brain in a fancy stemmed glass and pour hot chocolate over it.


22 posted on 07/15/2022 7:00:59 PM PDT by MayflowerMadam
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20% fewer pings) or “Everything” list.

23 posted on 07/15/2022 7:26:57 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: TigersEye

How many of us immediately thought of that scene? I sure did! Thanks for finding that great pic.


24 posted on 07/15/2022 8:08:37 PM PDT by ProtectOurFreedom (“...see whether we in our day and generation may not perform something worthy to be remembered.”)
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To: Red Badger

The rats tell us all we need to know, eh?


25 posted on 07/15/2022 9:05:52 PM PDT by Getready (Wisdom is more valuable than gold and diamonds, and harder to find.)
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To: FlingWingFlyer
"....What are the effects if you eat it on the sofa?"

With or without your girlfriend?

26 posted on 07/16/2022 6:00:43 AM PDT by GaltAdonis
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To: Red Badger
News flash, women crave chocolate during their time of menstruating because that is when their body is low on serotonin (sp?). Guess what chocolate is loaded with? You guessed it serotonin.

Gee, the World makes sense once again.

GOD built into our system an automatic meter that registers what we are missing. Thus when we need samba tour body gets from salt, we crave it, when our body needs what the sun gives us, we crave it.
When we have too much of what our body dies not need, our system usually rejects it, but our selfish brain o strides common sense which our system has.

Ever wonder why some people do not like shell fish? It's usually because they have an alerts to iodine which she'll fish is loaded with, aka chocolate glue loaded with sarato in and women at their time of the Month crave chocolate

27 posted on 07/16/2022 7:47:44 AM PDT by OneVike (Just another Christian waiting to go home)
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To: ProtectOurFreedom

:)


28 posted on 07/16/2022 1:39:32 PM PDT by TigersEye (The Democrat Party is criminal, unAmerican and illegitimate )
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To: Red Badger

I usually eat it on the chair.


29 posted on 07/16/2022 3:41:40 PM PDT by SunkenCiv (Imagine an imaginary menagerie manager imagining managing an imaginary menagerie.)
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