At long last, there might be a COVID treatment leftists won't denigrate: But how much will it cost?

One of the most peculiar things about COVID in America is that the powers that be — in politics, media, and medicine — have been hostile to the possibility of treating COVID. Since the virus emerged, people have been told there's nothing that can be done to treat COVID until they're near death, at which point...there's nothing that can be done to treat COVID. These same actors have hysterically opposed both the hydroxychloroquine cocktail and ivermectin. However, that resistance to early intervention may change now that Pfizer has a COVID-19 therapeutic antiviral protease inhibitor called PF-07321332.

PF-07321332 entered its phase two and three trials in August 2021. The treatment will be administered orally, although another version, called PF-07304814, is administered through an IV drip. According to Pfizer:

We believe that, if successful and authorized or approved, these investigational therapies could provide end-to-end treatment options for COVID-19 patients, including those exposed to the virus, those with diagnosed infections treated in the outpatient setting, and those hospitalized with moderate to severe infection.

Antiviral medications operate by interfering with a virus's ability to replicate in the body. If the medication is given early enough in the illness's progress, the infection will be weak. Protease inhibitors and other antivirals have been around for a long time for treating various illnesses, but they've only had off-label use in treating COVID cases. Pfizer's version, however, would be specific to SARS-CoV-2 treatment.

Early in the pandemic, existing antivirals, especially protease inhibitors, intrigued scientists. That's because they'd noticed that HIV patients already taking protease inhibitors for AIDS disease, if they caught COVID, mostly had surprisingly mild cases and unexpected survival rates. Also, in 2003, an earlier coronavirus — SARS-CoV-1 — responded well to protease inhibitors. Pfizer explained,

What this screenshot demonstrates is that Pfizer’s new twice-daily pill for Covid utilizes an unknown protease inhibitor, while including a snip from this study showing that Ivermectin also acts as a protease inhibitor.

Just another data point in favor of Ivermectin.

NIH Study — Ivermectin is ‘highly effective’ against key proteins of SARS-CoV-2 pathogenesis

Published online 2021 Apr 10

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8054936/

Ivermectin (IVM) is an FDA-approved drug that has shown antiviral activity against a wide variety of viruses in recent years.

This study explores the energetic and structural properties through which IVM inhibits importin-α and five targets associated with COVID-19 by using docking and MD simulations combined with the molecular mechanics generalized Born surface area (MMGBSA) approach.

IVM was submitted to phase III clinical trial in Thailand from 2014 to 2017 to treat dengue viral infection. As a result of this study, it was reported as safe when given as a single daily dose, which resulted in a significant decrease of serum levels of viral carriage (Yamasmith, 2018).

Previous experimental studies demonstrated that IVM could inhibit SARS-CoV-2 replication in vitro; however, IVM’s molecular mechanism inhibits binding to importin-α, and other SARS-CoV-2 receptors have not yet been elucidated.

They are knowingly preventing a treatment that works. The Gov, pharma, and doctors are not your friends.

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