Posted on 07/23/2021 4:39:27 PM PDT by ConservativeMind
You can't make a banana split without bananas. And you can't generate stable regulatory T cells without Vitamin C or enzymes called TET proteins, it appears.
Regulatory T cells (Tregs) help control inflammation and autoimmunity in the body. Tregs are so important, in fact, that scientists are working to generate stable induced Tregs (iTregs) in vitro for use as treatments for autoimmune diseases as well as rejection to transplanted organs. Unfortunately, it has proven difficult to find the right molecular ingredients to induce stable iTregs.
In their analysis, the researchers found TET proteins are absolutely required for maintaining the gene expression and epigenetic features that make Tregs as what they are; and adding Vitamin C led to iTregs with similar similar gene expression and epigenetic features as normal "wild type" Tregs found in the body. The study also reveals an intriguing connection between TET enzymatic activity, Vitamin C and IL-2/STAT5 signaling.
"In mice that are deficient for components of IL-2/STAT5 signaling, such as IL-2, IL-2 receptors or STAT5, the Tregs cannot develop properly or they can have impaired function," Yue says.
The researchers demonstrate that on one hand, TET-deficiency in Treg cells leads to impaired IL-2/STAT5 signaling; on the other hand, Vitamin C confers iTregs enhanced IL-2/STAT5 signaling by increasing the expression level of IL-2 receptor and the functional form of STAT5, and STAT5 binding to essential regions in the genome, rendering these cells survive better in tough environments with low IL-2 supplementation.
(Excerpt) Read more at sciencedaily.com ...
Another way to help is to take 1/4 to 1/2 a teaspoon of baking soda a day for two weeks, with which the following study shows our bodies start making more Tregs.
I drink a 12 oz glass of OJ every day.
Fauci takes Vit C & D....but he sure didn’t promote something so simple. Just take a multiple vit...what you use, you use...what you don’t goes in “the bowl”.
Just take a multiple vit...what you use, you use...what you don’t goes in “the bowl”.
Excess vitamin A is a common problem. The vitamin A you don’t use is stored in the liver. It eventually creates bone problems.
Which only works if you are not allergic to vitamin C.
I’m still trying to find one that doesn’t cause me to break out all over.
Wow, I hadn’t heard of this until you mentioned it.
https://www.livestrong.com/article/485015-ascorbic-acid-vitamin-c-allergies/
It does say non-supplement forms should be fine.
Natural forms:
https://www.healthline.com/nutrition/vitamin-c-foods
Also hibiscus tea:
https://www.doctorshealthpress.com/food-and-nutrition-articles/hibiscus-tea-benefits/
Metmom, I’m sorry you have this.
C is one of the water soluble vitamins, which is why it is quickly eliminated. The way around this is to take what is called “Liposomal” Vitamin C, which is fat soluble. Not only is it retained much longer, but it also penetrates the cell wall better. It can be purchased online.
“All your immunity are belong to us.”
We gave everybody with aids through the mrna spike protein injections.
No vitamin c. No hydroxychloroquine. No ivermectin. Banned.
Immunity is now pay to play.
Now worship Beast, slave.
The article does not give any recommendations regarding how much (i.e., how many mg. ) of Vitamin C the average person should take.
That is true. I would suggest taking something is better than nothing for this purpose.
ConsumerLab.com says 50-100 mg a day is the minimum we need, with any daily amount over 500 mg to 2,000 mg a day for colds, gout, high blood pressure, etc, increasing the risk of cataracts, according to studies.
https://www.consumerlab.com/reviews/vitamin-c-supplement-review/vitaminc/
From the vitamin C information, I’d say 500 mg a day, time release, would be the happy compromise.
“how many mg. ) of Vitamin C the average person should take.
Dr Linus Pauling, wo wrote the book on Vit C said you can’t take too much. I have been taking Vit C with Rose Hips for many years and I have never had to flu or even a cold. I take 2000 mil now because of covid. I take all the other recommended vitamins. D3, B12, Zink. I’ve stayed healthy so far (87).
Excellent point. When I was undergoing wound therapy several years back, the doctor treating me was also a specialist in this sort of thing. He’d described pictures taken at municipal waste treatment plants, where they separated various types of solid waste from the water, not just your ‘leavings’ but other organic/inorganic detrius. He said that huge piles of OTC meds were sifted out, much of it in the form of pills people take, and one of the big ones was vitamins. He told me that they didn’t completely digest in your digestive tract, so much of the nutrient value flushes out of the body. He espoused either liquicaps, which dissolve almost immediately upon hitting the stomach, or gummies, which are semi-digested while you’re chewing them. I’ve been a gummie advocate ever since. Thanks.
I can’t even think of touching high vitamin C fruits or veggies anymore.
Used to be I’d just break out bad with eczema.
But now it seems to have gone internal and my whole digestive system feels like it’s on fire.
I think it’s the histamine that is causing the burning.
Liposomal Vitamin C:
https://draxe.com/nutrition/liposomal-vitamin-c/
Liposomal Vitamin C may be up to 70x more absorbable (or take 1/70-seems too good to be true, but study reference is given):
https://www.amandean.com/blogs/news/liposomal-vitamin-c-and-allergies-what-is-the-connection
Liposomal Vitamin C bypasses several conversion steps which might have problems:
“Because they bypass the normal mechanism of absorbing vitamin C through slow vitamin C receptors type 1 (sodium-dependent vitamin C receptors SCVT 1), the bioavailability is much higher than standard vitamin C supplements.”
https://coremedscience.com/blogs/wellness/how-to-pick-the-best-liposomal-vitamin-c
.
Please take a look at the baking soda study referenced above (1/4 teaspoon a day for two weeks made the spleen encourage Treg cells that subdued all sorts of inflammation).
Of course, lower Omega-6 fats, increase Omega-3 fats, take vitamin D3, and antioxidants to further reduce inflammatory responses. There are other things to do the same, as well.
I have to believe there are ways to help turn this around, Metmom.
Bkmk
I was taking liposomal vitamin c because I thought the same way. I was listening to Dr. Marik and Dr. Kory of FLCCC fame and during the Q&A section of this week’s podcast/video, one of them said liposomal isn’t more effective….as the lipid shell gets broken down in the gut and that limits uptake just like normal oral vitamin c.
I haven’t researched it yet but Dr. Marik would know his vitamin C since he pioneered using IV vitamin c for the treatment of sepsis.
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