New Research Shows High Vitamin D Levels May Protect Against COVID-19, Especially for Black People

In a retrospective study of individuals tested for COVID-19, vitamin D levels above those traditionally considered sufficient were associated with a lower risk of COVID-19.

A new research study at the University of Chicago Medicine has found that when it comes to COVID-19, having vitamin D levels above those traditionally considered sufficient may lower the risk of infection, especially for Black people.

The study, published today (March 19, 2021) in JAMA Open Network, retrospectively examined the relationship between vitamin D levels and likelihood of testing positive for COVID-19. While levels of 30 ng/ml or more are usually considered “sufficient,” the authors found that Black individuals who had levels of 30 to 40 ng/ml had a 2.64 times higher risk of testing positive for COVID-19 than people with levels of 40 ng/ml or greater. Statistically significant associations of vitamin D levels with COVID-19 risk were not found in white people. The study looked at data from over 3,000 patients at UChicago Medicine who had had their vitamin D levels tested within 14 days before a COVID-19 test.

The research team is now recruiting participants for two separate clinical trials testing the efficacy of vitamin D supplements for preventing COVID-19.

This research is an expansion of an earlier study showing that a vitamin D deficiency (less than 20 ng/ml) may raise the risk of testing positive for COVID-19. In the current study, those results were further supported, finding that individuals with a vitamin D deficiency had a 7.2% chance of testing positive for the virus. A separate study recently found that over 80% of patients diagnosed with COVID-19 were vitamin D deficient.

“These new results tell us that having vitamin D levels above those normally considered sufficient is associated with decreased risk of testing positive for COVID-19, at least in Black individuals,” said David Meltzer, MD, PhD, Chief of Hospital Medicine at UChicago Medicine and lead author of the study. “This supports arguments for designing clinical trials that can test whether or not vitamin D may be a viable intervention to lower the risk of the disease, especially in persons of color.”

Meltzer was inspired to investigate this topic after seeing an article in early 2020 that found people with vitamin D deficiency who had randomly been assigned to receive vitamin D supplementation had much lower rates of viral respiratory infections compared to those who did not receive supplementation. He decided to examine data being collected at UChicago Medicine on COVID-19 to determine the role that vitamin D levels might be playing.

“There’s a lot of literature on vitamin D. Most of it has been focused on bone health, which is where the current standards for sufficient vitamin D levels come from,” Meltzer explained. “But there’s also some evidence that vitamin D might improve immune function and decrease inflammation. So far, the data has been relatively inconclusive. Based on these results, we think that earlier studies may have given doses that were too low to have much of an effect on the immune system, even if they were sufficient for bone health. It may be that different levels of vitamin D are adequate for different functions.”

Vitamin D can be obtained through diet or supplements, or produced by the body in response to exposure of the skin to sunlight. Meltzer noted that most individuals, especially people with darker skin, have lower levels of vitamin D; roughly half of the world’s population has levels below 30ng/ml. “Lifeguards, surfers, those are the kinds of folks who tend to have more than sufficient vitamin D levels,” he said. “Most folks living in Chicago in the winter are going to have levels that are well below that.”

While vitamin D supplements are relatively safe to take, excessive consumption of vitamin D supplements is associated with hypercalcemia, a condition in which calcium builds up in the blood stream and causes nausea, vomiting, weakness, and frequent urination. If left unchecked, it can further lead to bone pain and kidney stones.

“Currently, the adult recommended dietary allowance for vitamin D is 600 to 800 international units (IUs) per day,” said Meltzer. “The National Academy of Medicine has said that taking up to 4,000 IUs per day is safe for the vast majority of people, and risk of hypercalcemia increases at levels over 10,000 IUs per day.”

One of the challenges of this study is that it is currently difficult to determine exactly how vitamin D may be supporting immune function. “This is an observational study,” said Meltzer. “We can see that there’s an association between vitamin D levels and likelihood of a COVID-19 diagnosis, but we don’t know exactly why that is, or whether these results are due to the vitamin D directly or other related biological factors.”

Prompted by the evidence that people with vitamin D deficiency are more likely to test positive for COVID-19 and experience significant symptoms, a team at the University of Chicago and Rush University is conducting two studies to learn whether taking a daily vitamin D supplement can help prevent COVID-19 or decrease the severity of its symptoms.

Individuals who would like to learn more about the study and determine their eligibility can visit https://chess.uchicago.edu/vitamind/

Reference: “Association of Vitamin D Levels, Race/Ethnicity, and Clinical Characteristics with COVID-19 Test Results” by Thomas J. Best, Hui Zhang, Tamara Vokes, Vineet M. Arora and Julian Solway, 19 March 2021, JAMA Network Open. DOI: 10.1001/jamanetworkopen/2021.4117

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SUCCESSFUL THERAPY AGAINST COVID-19 VIRUS from New York State:
Dr. Vladimir (Zev) Zelenko
Board Certified Family Practitioner
501 Rt 208, Monroe, NY 10950
845-238-0000
March 23, 2020
To all medical professionals around the world:
My name is Dr. Zev Zelenko and I practice medicine in Monroe, NY. For the last 16 years, I have cared for approximately 75% of the adult population of Kiryas Joel, which is a very close knit community of approximately 35,000 people in which the infection spread rapidly and unchecked prior to the imposition of social distancing.
As of today my team has tested approximately 200 people from this community for Covid-19, and 65% of the results have been positive. If extrapolated to the entire community, that means more than 20,000 people are infected at the present time. Of this group, I estimate that there are 1500 patients who are in the high-risk category (i.e. >60, immunocompromised, comorbidities, etc).
Given the urgency of the situation, I developed the following treatment protocol in the pre-hospital setting and have seen only positive results:
1. Any patient with shortness of breath regardless of age is treated.
2. Any patient in the high-risk category even with just mild symptoms is treated.
3. Young, healthy and low risk patients even with symptoms are not treated (unless their circumstances change and they fall into category 1 or 2).
My out-patient treatment regimen is as follows:
1. Hydroxychloroquine 200mg twice a day for 5 days
2. Azithromycin 500mg once a day for 5 days
3. Zinc sulfate 220mg once a day for 5 days
The rationale for my treatment plan is as follows. I combined the data available from China and South Korea with the recent study published from France (sites available on request). We know that hydroxychloroquine helps Zinc enter the cell. We know that Zinc slows viral replication within the cell. Regarding the use of azithromycin, I postulate it prevents secondary bacterial infections. These three drugs are well known and usually well tolerated, hence the risk to the patient is low.
Since last Thursday, my team has treated approximately 350 patients in Kiryas Joel and another 150 patients in other areas of New York with the above regimen.
Of this group and the information provided to me by affiliated medical teams, we have had ZERO deaths, ZERO hospitalizations, and ZERO intubations. In addition, I have not heard of any negative side effects other than approximately 10% of patients with temporary nausea and diarrhea.
In sum, my urgent recommendation is to initiate treatment in the outpatient setting as soon as possible in accordance with the above. Based on my direct experience, it prevents acute respiratory distress syndrome (ARDS), prevents the need for hospitalization and saves lives.
With much respect,
Dr. Zev Zelenko
cc: President Donald J. Trump; Mr. Mark Meadows, Chief of Staff
Video at Link
https://matzav.com/watch-kiryas-yoel-dr-zev-zelenko-to-trump-im-seeing-success-with-your-approved-drug/?fbclid=IwAR0gVHAW9kWF-JLRHjzQx9bSFx6jlRgTn9_PpAmaiykXhsVqTE7wJrddS4g

8 posted on 3/24/2020, 5:02:30 PM by Candor7 ((Obama Fascism)http://www.americanthinker.com/articles/2009/05/barack_obam_the_quintessentia_1.html))
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EDITORIAL, not a medical professional:
Most likely, we are all going to get this, or have a loved one who does, or we’ve already had it.

Because the Hydroxychloroquine (quinine derivative) is such an old, well-known and tolerated drug, (used world-wide for malaria without prescription for over 70 years) and is generic, which means it is quite cheap and will not make huge profits, it is being denigrated and withheld as much as possible.

Try to get your doctor to prescribe it, and then a pharmacy to fill it.
It is commonly prescribed long-term for autoimmune diseases such as rheumatiod arthritis and lupus.

For those of us who can’t get this Hydroxychloroquine (HCQ) for whatever reason, there are substitutes. So keep this information, look it up, try it out when you or your loved one gets sick. .

Here are some substitutes:

1. Hydroxychloroquine (HCQ) (Quinine derivative) 200mg twice a day for 5 days
SCHWEPPS Tonic Water contains 80mg per liter of QUININE. 3 liters of the stuff will have about 240mg of Quinine. 5 liters will give you the same daily amount as above (200mg twice day = 400mg)
They tell you to push fluids when sick. So, SCHWEPPS Tonic water. Try the 3 liters. Get zinc in cells.

2. Azithromycin (Zpak) 500mg once a day for 5 days
Can’t get Zpak? If you take enough vitamin C (10-20 grams per day, spaced out about a gram (1000 mg ) per hour, it acts like an antibiotic. Maybe dissolve in the tonic, but don’t take pills on an empty stomach. If your stool gets soft, skip three hours and dial it back to a gram every other hour. (But you will absorb more vitamin c than you ever thought you could.)

3. Zinc sulfate 220mg once a day for 5 days. (THE ZINC IS THE ANTIVIRAL AGENT)
Zinc piccolinate, zinc glycinate, zinc gluconate supplements, all seem to work just fine. Check locally, order Amazon, or Puritans Pride www.puritan.com stock #2000 will work, or LifeExtension Foundation#01561 or #01961 www.lef.org. Advise the zinc 220mg dose for 5 days, then back to RDA of 22-25mg daily..

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