From the web: "Even moderately high intakes of zinc of about 60 milligrams per day for up to 10 weeks have been reported to reduce a copper-containing enzyme (a marker of copper status). Zinc supplements also have the potential to interact with several types of medications (such as antibiotics and diuretics). As such, be sure to discuss your zinc intake with your healthcare provider.”
In regards to dosing, humans are tolerant of doses up to 10 times the recommended daily dose by the WHO (daily recommended dose = 8-11mg elemental zinc).The doses used in registered clinical trials for COVID-19 vary between studies, with a maximum dose of zinc sulfate 220 mg.