Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Human Ancestors Were Consuming Alcohol 10 Million Years Ago
Discover 'blogs ^ | December 1, 2014 | Carl Engelking

Posted on 12/25/2014 4:40:58 PM PST by SunkenCiv

Using the tools of paleogenetics, scientists have recently traced the evolutionary history of an enzyme that helps us metabolize ethanol, the principal type of alcohol found in adult beverages. Scientists believe early human ancestors evolved their ethanol-digesting ability about 10 million years ago to fortify their diet as they shifted from a tree-based lifestyle to a more ground-based lifestyle...

To help narrow that range, researchers studied the genetic evolution of alcohol-metabolizing enzyme ADH4, which has been present in primates, in one form or another, for at least 70 million years. Using genetic sequences from 28 different mammals, including 17 primates, the researchers were able to work backward and create a sort of family tree for ADH4.

To see how the past versions would have worked, researchers then synthesized nine different ADH4 proteins and tested their ethanol-busting properties.

Nearly all of the ADH4 enzymes from our primate ancestors were inactive -- meaning they didn't break down ethanol. However, about 10 million years ago, when orangutans and human ancestors diverged, things changed dramatically. A single amino acid alteration made ADH4 able to metabolize ethanol 40 times better than before.

(Excerpt) Read more at blogs.discovermagazine.com ...


TOPICS: History; Science; Travel
KEYWORDS: adh4; alcohol; alcoholenzyme; dietandcuisine; enzyme; ethanol; godsgravesglyphs; helixmakemineadouble; oenology; zymurgy
Navigation: use the links below to view more comments.
first previous 1-2021-4041-6061-8081-84 last
To: BroJoeK

Acrually, it isn’t.

Many scientists were booted for discussions of this nature.

I pop in, make sure lurkers know we have people who know science, then pop out.

As I am doing now.


81 posted on 12/26/2014 2:27:34 PM PST by freedumb2003 (AGW: Settled Science? If so, there would only be one model and it would agree with measurements)
[ Post Reply | Private Reply | To 76 | View Replies]

To: freedumb2003
Freedumb233: "Many scientists were booted for discussions of this nature."

I doubt it, but perhaps you can cite known specifics & statistics?

82 posted on 12/27/2014 5:55:38 AM PST by BroJoeK (a little historical perspective.)
[ Post Reply | Private Reply | To 81 | View Replies]

To: BroJoeK

>>I doubt it, but perhaps you can cite known specifics & statistics?<<

ME (I was allowed back after 2 years) and about 30 others. We started Darwin Central but sadly that had a massive server collapse and has not returned.

I warn you to be very, very careful. And do NOT post about TToE on the Religion Forum!


83 posted on 12/27/2014 10:28:36 AM PST by freedumb2003 (AGW: Settled Science? If so, there would only be one model and it would agree with measurements)
[ Post Reply | Private Reply | To 82 | View Replies]

To: BroJoeK
I doubt it, but perhaps you can cite known specifics & statistics?

A lot of the Crevo war threads have been pulled, but most of the people who were banned let themselves get baited into joining a flame war.

84 posted on 12/27/2014 10:37:23 AM PST by tacticalogic
[ Post Reply | Private Reply | To 82 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-4041-6061-8081-84 last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson