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Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco and Dorothy Caputo, MA, BSN, RN, Nurse Planner Action Points Certain variations in the vitamin D receptor gene may influence the clinical effects of low vitamin D levels in some chronic diseases.Note that patients in the cohort without the genetic polymorphism showed no association between low 25(OH)D levels and outcomes such as hip fracture, myocardial infarction, cancer, and death. Variations in the vitamin D receptor gene may influence the clinical effects of low vitamin D levels in some chronic diseases, researchers found.Among patients with low serum 25-hydroxyvitamin...

Vitamin D Deficiency Study Raises New Questions About Disease And Supplements ScienceDaily (Jan. 27, 2008) — Low blood levels of vitamin D have long been associated with disease, and the assumption has been that vitamin D supplements may protect against disease. However, this new research demonstrates that ingested vitamin D is immunosuppressive and that low blood levels of vitamin D may be actually a result of the disease process. Supplementation may make the disease worse. In a new report Trevor Marshall, Ph.D., professor at Australia’s Murdoch University School of Biological Medicine and Biotechnology, explains how increased vitamin D intake affects...