Leaves of the European chestnut (Castanea sativa) contain ingredients with the power to block the virulence and pathogenesis of Staphylococcus aureus without detectable resistance, a new study has found. Rather than killing Staphylococcus aureus, the chestnut leaf extract — rich in oleanene and ursene derivatives (pentacyclic triterpenes) — works by taking away bacteria's weapons, essentially shutting off the ability of the bacteria to create toxins that cause tissue damage. "We have demonstrated in the lab that our extract disarms even the hyper-virulent MRSA (methicillin-resistant Staphylococcus aureus) strains capable of causing serious infections in healthy athletes," said Dr Cassandra Quave of...
