Free Republic

The Study of Administration (1887), by Woodrow Wilson, sets the stage for the bureaucracies that would follow it a little over a dozen years after it's publication. Starting roughly in the 20th century, the progressive era saw the explosive growth of administrative agencies lacking any oversight whatsoever, a malady we suffer under to this day over 120 years later. Unique among all generations of Americans before them, the progressives hated the United States Constitution, and Administration was their answer once and for all to get around this pesky obstacle we have all come to know and love.

It’s a question those of us in the gun writing business often get asked. “What’s the best caliber for a self-defense handgun?” Those expecting a one-to-three digit answer from me will be disappointed. I respond to their simple question with a complex one. “What is the most powerful cartridge that you can shoot accurately and proficiently that comes in a handgun which is comfortable enough to carry that you’ll carry it all the time?” Depending on the person asking, the answer will vary. For some, it’s a full-sized .357 Mag. or 10 mm Auto. For others, it’s one of the...

Frederick Douglass defends the Constitution. Many abolitionists in his day had misguided views about the Founding Fathers and the Constitution. Douglass was ready to set them straight.

Abstract Background: There is a recognized need to determine influenza vaccine effectiveness on an annual basis and a long history of studying respiratory illnesses in households. Methods: We recruited 328 households with 1441 members, including 839 children, and followed them during the 2010-2011 influenza season. Specimens were collected from subjects with reported acute respiratory illnesses and tested by real-time reverse transcriptase polymerase chain reaction. Receipt of influenza vaccine was defined based on documented evidence of vaccination in medical records or an immunization registry. The effectiveness of 2010-2011 influenza vaccination in preventing laboratory-confirmed influenza was estimated using Cox proportional hazards models...

CULVER CITY, CA—Trans woman Amy Schneider broke a winnings record on Jeopardy last week, earning more than any female contestant in the show's history. Experts say this proves once and for all that men really are smarter than women. "As a biological male, Schneider is once again proving the vast superiority of the male intellect," said MIT researcher Dr. Yamblo Figlenstrogg. "For better or for worse, this will be a huge boost for sexists and transphobes everywhere!" Audience members were reportedly in awe to find that Schneider's dress and pretty hair did not negatively affect the functioning of her brilliant...

In 2022, Earth is overpopulated and totally polluted; the natural resources have been exhausted and the nourishment of the population is provided by Soylent Industries, a company that makes a food consisting of plankton from the oceans.

(StudyFinds.org) – Although studies show COVID-19 is capable of infecting a patient’s kidneys, the virus’s exact impact on the organs has been unclear – until now. A team of German and Dutch scientists report COVID-19 causes direct cellular damage within the kidneys, contributing to tissue scarring. Conducted at the RWTH Uniklinik Aachen in Germany and the Radboud University Medical Center in the Netherlands, study authors assessed and compared kidney tissues among COVID-19 ICU patients, other patients in the hospital for a non-COVID-related lung issue, and a group of healthy people. Results show kidney tissue from the COVID-19 patients showed much...

An interesting thing happened yesterday! A manager at work was talking about the deteriorating political situation and to paraphrase, said the following: He tends to lean toward the liberal side (his lifestyle would truly indicate this, but no further comment), but he simply can not support some of the policies and spending they are trying to force down people's throats. He stated very plainly he can NOT support them because of the things they are advocating. I was in shock. I have NEVER heard a Democrat talk like that. The Democrats have to already know this in regard to their...

“Blake Percival is one of the most important whistleblowers in recent history,” Attorney Larry Golston says. “We as a country are safer because of what he did.” Blake Percival was born in Panama City, Florida where he was raised in a traditional Southern home. He graduated from High School in Montgomery, Alabama in 1984 and served 6 years in the U.S. Army where he was Honorably discharged at the rank of Sergeant in 1992. He then worked as a Police officer in West Virginia and Alabama. He is a graduate of the West Virginia State Police Academy, The Montgomery Police...

PHOENIX (3TV/CBS 5) -- Hospitals are slammed across Arizona. The state is asking the federal government for help with staffing, and Yavapai County is so inundated, it's running out of room at its morgue. Thursday, Yavapai County Community Health Services said it's requesting a refrigerated truck because so many people are dying from COVID. Their morgue is close to capacity, and they need to be prepared. In Maricopa County, public health leaders said it's not that bad here yet, although they are watching those numbers closely. "January marks two years from the first COVID-19 case in Maricopa County," said Marcy...

On a regional Mensa forum, I posted analysis of problems in education. To my delight, an indignant parent left her assessment of how bad our schools have become. First-person reports from the trenches are the most reliable intelligence you can get about this murky and unintelligent demimonde:: ----"I read your article and couldn't agree more. I have lived it with my twins for the last 13 years. I nearly cried when we moved from a NYC public school to a school district in an affluent part of NJ only to find out they had the same mind-numbing constructivist Math program...

Speech and guns: two of the most contentious issues in America today, with controversies fueled not only by personal passions and identity politics but by competing interpretations of the Constitution. Perhaps more than any other parts of the Constitution, the First and Second Amendments inspire religious-like fervor in many Americans, with accordingly irrational results. As legal texts go, neither of the two amendments is a model of clarity or precision. More important, both are deeply flawed in their respective conceptualizations of some of the most important rights of a democratic society: the freedom of expression and religion and the right...

Abstract A key driver in biopharmaceutical investment decisions is the probability of success of a drug development program. We estimate the probabilities of success (PoSs) of clinical trials for vaccines and other anti-infective therapeutics using 43,414 unique triplets of clinical trial, drug, and disease between January 1, 2000, and January 7, 2020, yielding 2,544 vaccine programs and 6,829 nonvaccine programs targeting infectious diseases. The overall estimated PoS for an industry-sponsored vaccine program is 39.6%, and 16.3% for an industry-sponsored anti-infective therapeutic....We plot the number of development programs known to start in each month from January 2000 through December 2019 in...

The probability of success (POS) of a clinical trial is critical for clinical researchers and biopharma investors to evaluate when making scientific and economic decisions. Prudent resource allocation relies on the accurate and timely assessment of risk. Without up-to-date estimates of the POS, however, investors may misjudge the risk and value of drug development, leading to lost opportunities for both investors and patients....The trials range from January 1, 2000, to October 31, 2015, the latter being the date that we received the data set... Of these, 34.7% (141,086) are industry sponsored and 65.3% (264,952) are non-industry sponsored. ...Table 1 contains...

QuestionShould I use you and me or you and I? Answer Whether to use I or me depends on whether the phrase is the subject of the sentence or the object of the sentence. I is a subject pronoun, and the subject is the person or thing doing the action as in "I went to the store." Me is an object pronoun, and the object is the person or thing the action happens to as in "Alex liked me." Use you and I when it is the subject of the sentence; use you and me when it is the object...

This is the port of Long Beach California. It is the second largest Port in North America, Ahead of the 3rd largest Port of New York, and Behind the largest Port which is the port of los angeles. Roughly 16 million Tons of Cargo pass through this port each year and makes its way to warehouses, factories, and homes, within the United States. This single port which is just 13 square kilometres, is responsible for well over $100 Billion dollars worth of trade and employs over 340 000 people in southern california. So, it is quite apparent that this port...

Want to command respect as if you were a badass Russian villain in a Hollywood film? Reckon you can do a better job than Harrison Ford’s questionable attempt at a Russian accent? Russia Beyond has you covered. A Russian accent is often imitated by English-speakers but rarely perfected. You’ll probably be familiar with the mean-sounding tone usually heard in Hollywood Russian accents, but do you know which sounds Russian speakers most commonly carry through to their spoken English? Follow these tricks, and you’ll be sounding like a native in no time! 1. Replace the 'i' with 'ee' There is no...

Japan began administering COVID-19 booster shots to health care workers nationwide on Wednesday (1 Dec) as the country braces for the potential impact of the omicron variant, a concerning new strain of the coronavirus that scientists worldwide are scrambling to research.Five doctors and 13 nurses at the state-run Tokyo Medical Center in Meguro Ward received their third jabs Wednesday morning. The hospital’s director, Kazuhiro Araki, who got the shot, said he feels relieved that the rollout began as scheduled.Medical personnel at Tokyo Medical University’s Hachioji Medical Center and some hospitals in Aichi and Saitama prefectures, among other facilities, also received...

Muslims by the millions are converting to Christianity. This has never happened before, and the astounding explanation given by many of the converts is that they are seeing dreams and visions of Jesus.

To the learned few words. Omicron, descrambled means 'moronic'. "Just saying..." mo·ron·ic (mə-rŏn′ĭk, mô-) adj. 1. Showing foolishness or stupidity. 2. Exhibiting mild intellectual disability. The term belongs to a classification system no longer in use and is now considered offensive. mo·ron′i·cal·ly adv. In oth