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Keyword: goodcholesterol

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  • 'Good cholesterol' nanoparticles seek and destroy cancer cells (siRNA nanoparticles)

    04/01/2011 12:26:50 PM PDT · by decimon · 5 replies
    Scientists package HDL with gene-silencing siRNA to target tumors, spare normal tissueHOUSTON - High-density lipoprotein's hauls excess cholesterol to the liver for disposal, but new research suggests "good cholesterol" can also act as a special delivery vehicle of destruction for cancer. Synthetic HDL nanoparticles loaded with small interfering RNA to silence cancer-promoting genes selectively shrunk or destroyed ovarian cancer tumors in mice, a research team led by scientists from The University of Texas MD Anderson Cancer Center and the University of North Texas Health Science Center reports in the April edition of Neoplasia. "RNA interference has great therapeutic potential but...
  • Test Drug Said to Increase Good Cholesterol

    04/07/2004 9:24:26 PM PDT · by neverdem · 3 replies · 1,129+ views
    NY Times ^ | April 8, 2004 | NA (AP)
    An experimental drug can sharply increase levels of H.D.L., the good cholesterol, potentially offering an entirely new way to help prevent heart attacks, researchers have found. In a preliminary study, researchers at the University of Pennsylvania and Tufts University found that the drug doubled H.D.L., or high density lipoprotein, in people with worrisomely low levels of the cholesterol. The drug, called torcetrapib, also reduced low density lipoprotein, or L.D.L., the bad cholesterol. Until now, doctors have concentrated largely on lowering bad cholesterol by giving patients statin drugs, which are used by millions of Americans and reduce heart attacks by about...